SH3 and multiple ankyrin repeat domains 3

mammalian protein found in Mus musculus

Protein protein Q21986777

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SH3 and multiple ankyrin repeat domains 3

Summary

SH3 and multiple ankyrin repeat domains 3 is a protein^[1].

Key Facts

SH3 and multiple ankyrin repeat domains 3's instance of is recorded as protein^[2].
SH3 and multiple ankyrin repeat domains 3's UniProt protein ID is recorded as Q4ACU6^[3].
SH3 and multiple ankyrin repeat domains 3's part of is recorded as SH3-like domain superfamily^[4].
SH3 and multiple ankyrin repeat domains 3's part of is recorded as PDZ superfamily^[5].
SH3 and multiple ankyrin repeat domains 3's part of is recorded as Sterile alpha motif/pointed domain superfamily^[6].
SH3 and multiple ankyrin repeat domains 3's part of is recorded as Ankyrin repeat-containing domain superfamily^[7].
SH3 and multiple ankyrin repeat domains 3's part of is recorded as membrane protein^[8].
SH3 and multiple ankyrin repeat domains 3's part of is recorded as Sterile alpha motif domain, protein family^[9].
SH3 and multiple ankyrin repeat domains 3's part of is recorded as PDZ domain, protein family^[10].
SH3 and multiple ankyrin repeat domains 3's part of is recorded as Ankyrin repeat-containing domain, protein family^[11].
SH3 and multiple ankyrin repeat domains 3's part of is recorded as SH3 domain, protein family^[12].
SH3 and multiple ankyrin repeat domains 3's part of is recorded as Ankyrin repeat, protein family^[13].
SH3 and multiple ankyrin repeat domains 3's has part is recorded as ankyrin repeat-containing domain^[14].
SH3 and multiple ankyrin repeat domains 3's has part is recorded as sterile alpha motif domain^[15].
SH3 and multiple ankyrin repeat domains 3's has part is recorded as SH3 domain^[16].
SH3 and multiple ankyrin repeat domains 3's has part is recorded as ankyrin repeat^[17].
SH3 and multiple ankyrin repeat domains 3's has part is recorded as PDZ domain^[18].
SH3 and multiple ankyrin repeat domains 3's RefSeq protein ID is recorded as NP_067398^[19].
SH3 and multiple ankyrin repeat domains 3's RefSeq protein ID is recorded as XP_006521285^[20].
SH3 and multiple ankyrin repeat domains 3's RefSeq protein ID is recorded as XP_017172206^[21].
SH3 and multiple ankyrin repeat domains 3's PDB structure ID is recorded as 3O5N^[22].
SH3 and multiple ankyrin repeat domains 3's PDB structure ID is recorded as 5IZU^[23].
SH3 and multiple ankyrin repeat domains 3's molecular function is recorded as protein binding^[24].
SH3 and multiple ankyrin repeat domains 3's molecular function is recorded as actin binding^[25].
SH3 and multiple ankyrin repeat domains 3's molecular function is recorded as ionotropic glutamate receptor binding^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of SH3-like domain superfamily, PDZ superfamily, Sterile alpha motif/pointed domain superfamily, Ankyrin repeat-containing domain superfamily, membrane protein, Sterile alpha motif domain, protein family, PDZ domain, protein family, Ankyrin repeat-containing domain, protein family, SH3 domain, protein family, Ankyrin repeat, protein family

Properties

Biological process regulation of grooming behavior, positive regulation of long-term synaptic potentiation, positive regulation of synapse structural plasticity, embryonic epithelial tube formation, locomotory behavior, neuromuscular process controlling balance, NMDA glutamate receptor clustering, regulation of long-term synaptic depression, postsynaptic density assembly, negative regulation of cell volume, negative regulation of actin filament bundle assembly, positive regulation of AMPA receptor activity, memory, learning, positive regulation of dendritic spine development, MAPK cascade, regulation of synaptic plasticity, locomotory exploration behavior, striatal medium spiny neuron differentiation, AMPA glutamate receptor clustering, dendritic spine morphogenesis, vocal learning, vocalization behavior, adult behavior, positive regulation of synaptic transmission, glutamatergic, positive regulation of long-term neuronal synaptic plasticity, regulation of long-term synaptic potentiation, exploration behavior, locomotion, long-term depression, learning or memory, positive regulation of excitatory postsynaptic potential, regulation of AMPA glutamate receptor clustering, social behavior, guanylate kinase-associated protein clustering, synapse assembly, regulation of behavioral fear response, regulation of dendritic spine morphogenesis, brain morphogenesis, long-term potentiation, protein complex oligomerization, positive regulation of glutamate receptor signaling pathway, synapse assembly, brain morphogenesis, regulation of synapse organization, synaptic assembly at neuromuscular junction, positive regulation of synaptic transmission, glutamatergic, long-term potentiation, dendritic spine morphogenesis, positive regulation of dendritic spine development, postsynaptic density assembly, maintenance of postsynaptic density structure, regulation of AMPA receptor activity, positive regulation of excitatory postsynaptic potential

Cell component cytoplasm, postsynaptic membrane, cell projection, membrane, plasma membrane, dendritic spine, excitatory synapse, cell junction, neuron spine, neuron projection, postsynaptic density, synapse, ciliary membrane, NMDA selective glutamate receptor complex, plasma membrane, ionotropic glutamate receptor complex, postsynaptic density, dendrite, extrinsic component of cytoplasmic side of plasma membrane, neuron projection, dendritic spine, neuron spine, postsynaptic membrane, glutamatergic synapse, postsynaptic density, intracellular component

Encoded by Shank3

Found in taxon house mouse

Has part(s) ankyrin repeat-containing domain, sterile alpha motif domain, SH3 domain, ankyrin repeat, PDZ domain

Imported from wholeness_audit_2026-05-02

Molecular function protein binding, actin binding, ionotropic glutamate receptor binding, protein C-terminus binding, zinc ion binding, SH3 domain binding, synaptic receptor adaptor activity, identical protein binding, protein self-association, scaffold protein binding, signaling receptor complex adaptor activity, synaptic receptor adaptor activity, ionotropic glutamate receptor binding, structural constituent of postsynaptic density

External References (4)

Ensembl protein id ENSMUSP00000048062, ENSMUSP00000104932, ENSMUSP00000132229, ENSMUSP00000155608, ENSMUSP00000154842, ENSMUSP00000158668, ENSMUSP00000159275

Pdb structure id 3O5N, 5IZU

Refseq protein id NP_067398, XP_006521285, XP_017172206

Uniprot protein id Q4ACU6

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ SH3 and multiple ankyrin repeat domains 3 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ SH3 and multiple ankyrin repeat domains 3 — UniProt protein ID (P352): Q4ACU6. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ SH3 and multiple ankyrin repeat domains 3 — part of (P361): SH3-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ SH3 and multiple ankyrin repeat domains 3 — part of (P361): PDZ superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ SH3 and multiple ankyrin repeat domains 3 — part of (P361): Sterile alpha motif/pointed domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ SH3 and multiple ankyrin repeat domains 3 — part of (P361): Ankyrin repeat-containing domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ SH3 and multiple ankyrin repeat domains 3 — part of (P361): membrane protein. wikidata.org.
[9] ↑ SH3 and multiple ankyrin repeat domains 3 — part of (P361): Sterile alpha motif domain, protein family. wikidata.org.
[10] ↑ SH3 and multiple ankyrin repeat domains 3 — part of (P361): PDZ domain, protein family. wikidata.org.
[11] ↑ SH3 and multiple ankyrin repeat domains 3 — part of (P361): Ankyrin repeat-containing domain, protein family. wikidata.org.
[12] ↑ SH3 and multiple ankyrin repeat domains 3 — part of (P361): SH3 domain, protein family. wikidata.org.
[13] ↑ SH3 and multiple ankyrin repeat domains 3 — part of (P361): Ankyrin repeat, protein family. wikidata.org.
[14] ↑ SH3 and multiple ankyrin repeat domains 3 — has part(s) (P527): ankyrin repeat-containing domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ SH3 and multiple ankyrin repeat domains 3 — has part(s) (P527): sterile alpha motif domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ SH3 and multiple ankyrin repeat domains 3 — has part(s) (P527): SH3 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ SH3 and multiple ankyrin repeat domains 3 — has part(s) (P527): ankyrin repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ SH3 and multiple ankyrin repeat domains 3 — has part(s) (P527): PDZ domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ SH3 and multiple ankyrin repeat domains 3 — RefSeq protein ID (P637): NP_067398. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ SH3 and multiple ankyrin repeat domains 3 — RefSeq protein ID (P637): XP_006521285. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ SH3 and multiple ankyrin repeat domains 3 — RefSeq protein ID (P637): XP_017172206. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ SH3 and multiple ankyrin repeat domains 3 — PDB structure ID (P638): 3O5N. Q905695. Retrieved 2016-08-10. wikidata.org.
[23] ↑ SH3 and multiple ankyrin repeat domains 3 — PDB structure ID (P638): 5IZU. Q905695. Retrieved 2016-08-10. wikidata.org.
[24] ↑ SH3 and multiple ankyrin repeat domains 3 — molecular function (P680): protein binding. The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ SH3 and multiple ankyrin repeat domains 3 — molecular function (P680): actin binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ SH3 and multiple ankyrin repeat domains 3 — molecular function (P680): ionotropic glutamate receptor binding. Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor. Retrieved 2018-06-21. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ SH3 and multiple ankyrin repeat domains 3 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

“SH3 and multiple ankyrin repeat domains 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/sh3-and-multiple-ankyrin-repeat-domains-3-q21986777.

BibTeX

@misc{4ortxyz_sh3-and-multiple-ankyrin-repeat-domains-3-q21986777_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{SH3 and multiple ankyrin repeat domains 3}}, year = {2026}, url = {https://4ort.xyz/entity/sh3-and-multiple-ankyrin-repeat-domains-3-q21986777}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): SH3 and multiple ankyrin repeat domains 3 — https://4ort.xyz/entity/sh3-and-multiple-ankyrin-repeat-domains-3-q21986777 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/sh3-and-multiple-ankyrin-repeat-domains-3-q21986777 · Last refreshed: May 3, 2026