SH2 domain-containing protein 1B

mouse protein (annotated by UniProtKB/Swiss-Prot O35324)
Protein protein Q21991445
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SH2 domain-containing protein 1B

Summary

SH2 domain-containing protein 1B is a protein[1].

Key Facts

  • SH2 domain-containing protein 1B's instance of is recorded as protein[2].
  • SH2 domain-containing protein 1B's UniProt protein ID is recorded as O35324[3].
  • SH2 domain-containing protein 1B's part of is recorded as SH2 domain superfamily[4].
  • SH2 domain-containing protein 1B's part of is recorded as EAT-2, SH2 domain, protein family[5].
  • SH2 domain-containing protein 1B's part of is recorded as SH2 domain, protein family[6].
  • SH2 domain-containing protein 1B's has part is recorded as SH2 domain[7].
  • SH2 domain-containing protein 1B's has part is recorded as EAT-2, SH2 domain[8].
  • SH2 domain-containing protein 1B's PDB structure ID is recorded as 1I3Z[9].
  • SH2 domain-containing protein 1B's molecular function is recorded as phosphotyrosine residue binding[10].
  • SH2 domain-containing protein 1B's molecular function is recorded as protein binding[11].
  • SH2 domain-containing protein 1B's molecular function is recorded as signaling adaptor activity[12].
  • SH2 domain-containing protein 1B's cell component is recorded as intracellular anatomical structure[13].
  • SH2 domain-containing protein 1B's biological process is recorded as negative regulation of natural killer cell mediated cytotoxicity[14].
  • SH2 domain-containing protein 1B's biological process is recorded as peptidyl-tyrosine phosphorylation[15].
  • SH2 domain-containing protein 1B's biological process is recorded as positive regulation of signal transduction[16].
  • SH2 domain-containing protein 1B's biological process is recorded as negative regulation of interferon-gamma production[17].
  • SH2 domain-containing protein 1B's biological process is recorded as negative regulation of peptidyl-tyrosine phosphorylation[18].
  • SH2 domain-containing protein 1B's biological process is recorded as innate immune response[19].
  • SH2 domain-containing protein 1B's biological process is recorded as leukocyte activation involved in immune response[20].
  • SH2 domain-containing protein 1B's biological process is recorded as adaptive immune response[21].
  • SH2 domain-containing protein 1B's biological process is recorded as positive regulation of natural killer cell mediated cytotoxicity[22].
  • SH2 domain-containing protein 1B's biological process is recorded as natural killer cell inhibitory signaling pathway[23].
  • SH2 domain-containing protein 1B's biological process is recorded as positive regulation of natural killer cell mediated immunity[24].
  • SH2 domain-containing protein 1B's biological process is recorded as positive regulation of innate immune response[25].
  • SH2 domain-containing protein 1B's biological process is recorded as immune system process[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . wikidata.org.
  2. [3] ↑ . Q905695. Retrieved . wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . Q905695. Retrieved . wikidata.org.
  9. [10] ↑ . EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . Identification and characterization of two related murine genes, Eat2a and Eat2b, encoding single SH2-domain adapters. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] ↑ . Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] ↑ . Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] ↑ . Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). SH2 domain-containing protein 1B. Retrieved May 3, 2026, from https://4ort.xyz/entity/sh2-domain-containing-protein-1b
MLA “SH2 domain-containing protein 1B.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/sh2-domain-containing-protein-1b.
BibTeX @misc{4ortxyz_sh2-domain-containing-protein-1b_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{SH2 domain-containing protein 1B}}, year = {2026}, url = {https://4ort.xyz/entity/sh2-domain-containing-protein-1b}, note = {Accessed: 2026-05-03}}
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