SET domain containing 1A, histone lysine methyltransferase

mammalian protein found in Homo sapiens

Protein protein Q21115985

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SET domain containing 1A, histone lysine methyltransferase

Summary

SET domain containing 1A, histone lysine methyltransferase is a protein^[1].

Key Facts

SET domain containing 1A, histone lysine methyltransferase's instance of is recorded as protein^[2].
SET domain containing 1A, histone lysine methyltransferase's UniProt protein ID is recorded as O15047^[3].
SET domain containing 1A, histone lysine methyltransferase's part of is recorded as RNA-binding domain superfamily^[4].
SET domain containing 1A, histone lysine methyltransferase's part of is recorded as Nucleotide-binding alpha-beta plait domain superfamily^[5].
SET domain containing 1A, histone lysine methyltransferase's part of is recorded as Histone-lysine N-methyltransferase SETD1A^[6].
SET domain containing 1A, histone lysine methyltransferase's part of is recorded as COMPASS complex Set1 subunit, N-SET domain, protein family^[7].
SET domain containing 1A, histone lysine methyltransferase's part of is recorded as Post-SET domain, protein family^[8].
SET domain containing 1A, histone lysine methyltransferase's part of is recorded as SET domain, protein family^[9].
SET domain containing 1A, histone lysine methyltransferase's part of is recorded as Set1A, RNA recognition motif, protein family^[10].
SET domain containing 1A, histone lysine methyltransferase's part of is recorded as RNA recognition motif domain, protein family^[11].
SET domain containing 1A, histone lysine methyltransferase's has part is recorded as SET domain^[12].
SET domain containing 1A, histone lysine methyltransferase's has part is recorded as Post-SET domain^[13].
SET domain containing 1A, histone lysine methyltransferase's has part is recorded as RNA recognition motif domain^[14].
SET domain containing 1A, histone lysine methyltransferase's has part is recorded as COMPASS complex Set1 subunit, N-SET domain^[15].
SET domain containing 1A, histone lysine methyltransferase's has part is recorded as Set1A, RNA recognition motif^[16].
SET domain containing 1A, histone lysine methyltransferase's RefSeq protein ID is recorded as NP_055527^[17].
SET domain containing 1A, histone lysine methyltransferase's RefSeq protein ID is recorded as XP_005255780^[18].
SET domain containing 1A, histone lysine methyltransferase's RefSeq protein ID is recorded as XP_006721169^[19].
SET domain containing 1A, histone lysine methyltransferase's RefSeq protein ID is recorded as XP_016879398^[20].
SET domain containing 1A, histone lysine methyltransferase's RefSeq protein ID is recorded as XP_024306267^[21].
SET domain containing 1A, histone lysine methyltransferase's PDB structure ID is recorded as 3S8S^[22].
SET domain containing 1A, histone lysine methyltransferase's PDB structure ID is recorded as 3UVN^[23].
SET domain containing 1A, histone lysine methyltransferase's PDB structure ID is recorded as 4EWR^[24].
SET domain containing 1A, histone lysine methyltransferase's molecular function is recorded as methyltransferase activity^[25].
SET domain containing 1A, histone lysine methyltransferase's molecular function is recorded as transferase activity^[26].

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Quick Facts

Instance of protein

Part of RNA-binding domain superfamily, Nucleotide-binding alpha-beta plait domain superfamily, Histone-lysine N-methyltransferase SETD1A, COMPASS complex Set1 subunit, N-SET domain, protein family, Post-SET domain, protein family, SET domain, protein family, Set1A, RNA recognition motif, protein family, RNA recognition motif domain, protein family

Properties

Biological process regulation of transcription, DNA-templated, transcription, DNA-templated, methylation, histone H3-K4 methylation, regulation of hematopoietic stem cell differentiation, regulation of megakaryocyte differentiation, histone lysine methylation, regulation of chromatin organization, chromatin organization, positive regulation of gene expression, stem cell population maintenance, regulation of erythrocyte differentiation, regulation of chromatin organization, positive regulation of neural precursor cell proliferation, positive regulation of stem cell proliferation

Cell component chromosome, nucleus, histone methyltransferase complex, nucleoplasm, nuclear speck, Set1C/COMPASS complex

Encoded by SETD1A

Found in taxon Homo sapiens

Has part(s) SET domain, Post-SET domain, RNA recognition motif domain, COMPASS complex Set1 subunit, N-SET domain, Set1A, RNA recognition motif

Imported from wholeness_audit_2026-05-02

Molecular function methyltransferase activity, transferase activity, beta-catenin binding, protein binding, RNA binding, nucleic acid binding, histone-lysine N-methyltransferase activity, transcription factor binding, histone methyltransferase activity (H3-K4 specific), euchromatin binding, histone-lysine N-methyltransferase activity

External References (4)

Ensembl protein id ENSP00000262519, ENSP00000391408

Pdb structure id 3S8S, 3UVN, 4EWR

Refseq protein id NP_055527, XP_005255780, XP_006721169, XP_016879398, XP_024306267

Uniprot protein id O15047

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ SET domain containing 1A, histone lysine methyltransferase — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ SET domain containing 1A, histone lysine methyltransferase — UniProt protein ID (P352): O15047. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ SET domain containing 1A, histone lysine methyltransferase — part of (P361): RNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ SET domain containing 1A, histone lysine methyltransferase — part of (P361): Nucleotide-binding alpha-beta plait domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ SET domain containing 1A, histone lysine methyltransferase — part of (P361): Histone-lysine N-methyltransferase SETD1A. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ SET domain containing 1A, histone lysine methyltransferase — part of (P361): COMPASS complex Set1 subunit, N-SET domain, protein family. wikidata.org.
[8] ↑ SET domain containing 1A, histone lysine methyltransferase — part of (P361): Post-SET domain, protein family. wikidata.org.
[9] ↑ SET domain containing 1A, histone lysine methyltransferase — part of (P361): SET domain, protein family. wikidata.org.
[10] ↑ SET domain containing 1A, histone lysine methyltransferase — part of (P361): Set1A, RNA recognition motif, protein family. wikidata.org.
[11] ↑ SET domain containing 1A, histone lysine methyltransferase — part of (P361): RNA recognition motif domain, protein family. wikidata.org.
[12] ↑ SET domain containing 1A, histone lysine methyltransferase — has part(s) (P527): SET domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ SET domain containing 1A, histone lysine methyltransferase — has part(s) (P527): Post-SET domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ SET domain containing 1A, histone lysine methyltransferase — has part(s) (P527): RNA recognition motif domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ SET domain containing 1A, histone lysine methyltransferase — has part(s) (P527): COMPASS complex Set1 subunit, N-SET domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ SET domain containing 1A, histone lysine methyltransferase — has part(s) (P527): Set1A, RNA recognition motif. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ SET domain containing 1A, histone lysine methyltransferase — RefSeq protein ID (P637): NP_055527. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ SET domain containing 1A, histone lysine methyltransferase — RefSeq protein ID (P637): XP_005255780. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ SET domain containing 1A, histone lysine methyltransferase — RefSeq protein ID (P637): XP_006721169. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ SET domain containing 1A, histone lysine methyltransferase — RefSeq protein ID (P637): XP_016879398. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ SET domain containing 1A, histone lysine methyltransferase — RefSeq protein ID (P637): XP_024306267. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ SET domain containing 1A, histone lysine methyltransferase — PDB structure ID (P638): 3S8S. Q905695. Retrieved 2016-08-09. wikidata.org.
[23] ↑ SET domain containing 1A, histone lysine methyltransferase — PDB structure ID (P638): 3UVN. Q905695. Retrieved 2016-08-09. wikidata.org.
[24] ↑ SET domain containing 1A, histone lysine methyltransferase — PDB structure ID (P638): 4EWR. Q905695. Retrieved 2016-08-09. wikidata.org.
[25] ↑ SET domain containing 1A, histone lysine methyltransferase — molecular function (P680): methyltransferase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ SET domain containing 1A, histone lysine methyltransferase — molecular function (P680): transferase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ SET domain containing 1A, histone lysine methyltransferase is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). SET domain containing 1A, histone lysine methyltransferase. Retrieved May 3, 2026, from https://4ort.xyz/entity/set-domain-containing-1a-histone-lysine-methyltransferase

MLA

“SET domain containing 1A, histone lysine methyltransferase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/set-domain-containing-1a-histone-lysine-methyltransferase.

BibTeX

@misc{4ortxyz_set-domain-containing-1a-histone-lysine-methyltransferase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{SET domain containing 1A, histone lysine methyltransferase}}, year = {2026}, url = {https://4ort.xyz/entity/set-domain-containing-1a-histone-lysine-methyltransferase}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): SET domain containing 1A, histone lysine methyltransferase — https://4ort.xyz/entity/set-domain-containing-1a-histone-lysine-methyltransferase (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/set-domain-containing-1a-histone-lysine-methyltransferase · Last refreshed: May 3, 2026