Serine hydroxymethyltransferase 1

mammalian protein found in Homo sapiens
Protein protein Q21106202
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Serine hydroxymethyltransferase 1

Summary

Serine hydroxymethyltransferase 1 is a protein[1]. It is known by 7 alternative names across languages and contexts.[2]

Key Facts

  • Serine hydroxymethyltransferase 1's instance of is recorded as protein[3].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as transferase activity[4].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as serine binding[5].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as protein homodimerization activity[6].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as amino acid binding[7].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as L-allo-threonine aldolase activity[8].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as protein binding[9].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as catalytic activity[10].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as pyridoxal phosphate binding[11].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as identical protein binding[12].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as translation repressor activity, mRNA regulatory element binding[13].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as glycine hydroxymethyltransferase activity[14].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as mRNA 5'-UTR binding[15].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as translation repressor activity, mRNA regulatory element binding[16].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as glycine hydroxymethyltransferase activity[17].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as zinc ion binding[18].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as amino acid binding[19].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as pyridoxal phosphate binding[20].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as protein homodimerization activity[21].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as mRNA 5'-UTR binding[22].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as cobalt ion binding[23].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as serine binding[24].
  • Serine hydroxymethyltransferase 1's molecular function is recorded as glycine hydroxymethyltransferase activity[25].
  • Serine hydroxymethyltransferase 1's cell component is recorded as cytosol[26].
  • Serine hydroxymethyltransferase 1's cell component is recorded as mitochondrion[27].

Why It Matters

Serine hydroxymethyltransferase 1 is known by 7 alternative names across languages and contexts.[2]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . Q905695. Retrieved . wikidata.org.
  2. [4] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . Distinct biochemical properties of human serine hydroxymethyltransferase compared with the Plasmodium enzyme: implications for selective inhibition. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . A proteome-scale map of the human interactome network. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . A proteome-scale map of the human interactome network. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . Human cytoplasmic serine hydroxymethyltransferase is an mRNA binding protein. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . Human cytoplasmic serine hydroxymethyltransferase is an mRNA binding protein. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Human cytoplasmic serine hydroxymethyltransferase is an mRNA binding protein. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Human cytoplasmic serine hydroxymethyltransferase is an mRNA binding protein. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . Distinct biochemical properties of human serine hydroxymethyltransferase compared with the Plasmodium enzyme: implications for selective inhibition. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Serine hydroxymethyltransferase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/serine-hydroxymethyltransferase-1
MLA “Serine hydroxymethyltransferase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/serine-hydroxymethyltransferase-1.
BibTeX @misc{4ortxyz_serine-hydroxymethyltransferase-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Serine hydroxymethyltransferase 1}}, year = {2026}, url = {https://4ort.xyz/entity/serine-hydroxymethyltransferase-1}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 9w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → SHMT1
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → transferase activity, serine binding, protein homodimerization activity +19
    + 9 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.1.2.1, [[:toollabs:quickstatements/#/batch/261489|batch #261489]]"
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