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Senior-Loken syndrome

autosomal recessive genetic disease characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease
MedicalCondition rare_disease Q4354267
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Senior-Loken syndrome

Summary

Senior-Loken syndrome is a rare disease[1]. It draws 26 Wikipedia views per month (rare_disease category, ranking #233 of 627).[2]

Key Facts

  • Senior-Loken syndrome's instance of is recorded as rare disease[3].
  • Senior-Loken syndrome's instance of is recorded as class of disease[4].
  • Senior-Loken syndrome is a type of autosomal recessive disease[5].
  • Senior-Loken syndrome is a type of nephronophthisis[6].
  • Senior-Loken syndrome is a type of fundus dystrophy[7].
  • Senior-Loken syndrome is a type of syndrome[8].
  • Senior-Loken syndrome's ICD-9-CM is recorded as 759.89[9].
  • Senior-Loken syndrome's NCI Thesaurus ID is recorded as C168588[10].
  • Senior-Loken syndrome's health specialty is recorded as medical genetics[11].
  • Senior-Loken syndrome's genetic association is recorded as NPHP1[12].
  • Senior-Loken syndrome's genetic association is recorded as CEP290[13].
  • Senior-Loken syndrome's genetic association is recorded as NPHP4[14].
  • Senior-Loken syndrome's genetic association is recorded as SDCCAG8[15].
  • Senior-Loken syndrome's genetic association is recorded as IQCB1[16].
  • Senior-Loken syndrome's exact match is recorded as http://purl.obolibrary.org/obo/DOID_0050576[17].
  • Senior-Loken syndrome's exact match is recorded as http://identifiers.org/doid/DOID:0050576[18].
  • Senior-Loken syndrome's exact match is recorded as http://www.orpha.net/ORDO/Orphanet_3156[19].
  • Senior-Loken syndrome's on focus list of Wikimedia project is recorded as WikiProject Medicine[20].

Why It Matters

Senior-Loken syndrome draws 26 Wikipedia views per month (rare_disease category, ranking #233 of 627).[2] It has Wikipedia articles in 5 language editions, a strong signal of global cultural recognition.[21] It is known by 20 alternative names across languages and contexts.[22]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . wikidata.org.
  3. [5] ↑ . Disease Ontology. Retrieved . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . Disease Ontology. Retrieved . wikidata.org.
  7. [9] ↑ . Monarch Disease Ontology release 2018-06-29. Retrieved . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . wikidata.org.
  10. [12] ↑ . Q905695. Retrieved . wikidata.org.
  11. [13] ↑ . The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. wikidata.org.
  12. [14] ↑ . A gene mutated in nephronophthisis and retinitis pigmentosa encodes a novel protein, nephroretinin, conserved in evolution. wikidata.org.
  13. [15] ↑ . Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. wikidata.org.
  14. [16] ↑ . Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin. wikidata.org.
  15. [17] ↑ . Disease Ontology. Retrieved . wikidata.org.
  16. [18] ↑ . Identifiers.org. registry.identifiers.org. Provenance: wikidata.org.
  17. [19] ↑ . wikidata.org.
  18. [20] ↑ . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [21] ↑ . Wikidata sitelinks. wikidata.org.
  3. [22] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Senior-Loken syndrome. Retrieved May 3, 2026, from https://4ort.xyz/entity/senior-loken-syndrome
MLA “Senior-Loken syndrome.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/senior-loken-syndrome.
BibTeX @misc{4ortxyz_senior-loken-syndrome_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Senior-Loken syndrome}}, year = {2026}, url = {https://4ort.xyz/entity/senior-loken-syndrome}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Senior-Loken syndrome — https://4ort.xyz/entity/senior-loken-syndrome (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 7w ago · JhealdBatch bot · 2026-07-05 view diff on Wikidata ↗
    On focus list of wikimedia project → WikiProject Medicine
    Health specialty → medical genetics
    Subclass of → autosomal recessive disease, nephronophthisis, fundus dystrophy +1
    Subclass of → —
    + 4 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update:0| */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/39953|batch #39953]]: deprecate redundant disease superclasses (2)"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.