Senataxin

mammalian protein found in Homo sapiens
Protein protein Q21124479
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Senataxin

Summary

Senataxin is a protein[1]. Senataxin is known by 5 alternative names across languages and contexts.[2]

Key Facts

  • Senataxin's instance of is recorded as protein[3].
  • Senataxin is part of P-loop containing nucleoside triphosphate hydrolase[4].
  • Senataxin's molecular function is recorded as transcription termination site sequence-specific DNA binding[5].
  • Senataxin's molecular function is recorded as nucleotide binding[6].
  • Senataxin's molecular function is recorded as protein binding[7].
  • Senataxin's molecular function is recorded as ATP binding[8].
  • Senataxin's molecular function is recorded as helicase activity[9].
  • Senataxin's molecular function is recorded as DNA helicase activity[10].
  • Senataxin's molecular function is recorded as identical protein binding[11].
  • Senataxin's molecular function is recorded as hydrolase activity[12].
  • Senataxin's molecular function is recorded as DNA binding[13].
  • Senataxin's molecular function is recorded as transcription termination site sequence-specific DNA binding[14].
  • Senataxin's molecular function is recorded as RNA binding[15].
  • Senataxin's cell component is recorded as nucleolus[16].
  • Senataxin's cell component is recorded as telomere[17].
  • Senataxin's cell component is recorded as nuclear chromosome[18].
  • Senataxin's cell component is recorded as chromosome[19].
  • Senataxin's cell component is recorded as cell projection[20].
  • Senataxin's cell component is recorded as cytoplasm[21].
  • Senataxin's cell component is recorded as growth cone[22].
  • Senataxin's cell component is recorded as nucleoplasm[23].
  • Senataxin's cell component is recorded as axon[24].
  • Senataxin's cell component is recorded as nucleus[25].
  • Senataxin's cell component is recorded as nuclear body[26].
  • Senataxin's cell component is recorded as intercellular bridge[27].

Why It Matters

Senataxin is known by 5 alternative names across languages and contexts.[2]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] . Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [7] . Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] . Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] . Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Senataxin. Retrieved May 3, 2026, from https://4ort.xyz/entity/senataxin
MLA “Senataxin.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/senataxin.
BibTeX @misc{4ortxyz_senataxin_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Senataxin}}, year = {2026}, url = {https://4ort.xyz/entity/senataxin}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Senataxin — https://4ort.xyz/entity/senataxin (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/senataxin · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 7w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from
    Encoded by SETX
    Wikidata description mammalian protein found in Homo sapiens
    Molecular function transcription termination site sequence-specific DNA binding, nucleotide binding, protein binding +8
    + 9 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 5.6.2.3, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.