Scleraxis

mammalian protein found in Mus musculus
Protein protein Q21988090
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Scleraxis

Summary

Scleraxis is a protein[1].

Key Facts

  • Scleraxis's instance of is recorded as protein[2].
  • Scleraxis's subclass of is recorded as protein[3].
  • Scleraxis's UniProt protein ID is recorded as Eixample[4].
  • Scleraxis's part of is recorded as Helix-loop-helix DNA-binding domain superfamily[5].
  • Scleraxis's part of is recorded as Myc-type, basic helix-loop-helix (bHLH) domain, protein family[6].
  • Scleraxis's has part is recorded as Myc-type, basic helix-loop-helix (bHLH) domain[7].
  • Scleraxis's RefSeq protein ID is recorded as NP_942588[8].
  • Scleraxis's RefSeq protein ID is recorded as XP_006520723[9].
  • Scleraxis's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding[10].
  • Scleraxis's molecular function is recorded as DNA binding[11].
  • Scleraxis's molecular function is recorded as sequence-specific DNA binding[12].
  • Scleraxis's molecular function is recorded as protein dimerization activity[13].
  • Scleraxis's molecular function is recorded as bHLH transcription factor binding[14].
  • Scleraxis's molecular function is recorded as E-box binding[15].
  • Scleraxis's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific[16].
  • Scleraxis's molecular function is recorded as protein binding[17].
  • Scleraxis's molecular function is recorded as protein heterodimerization activity[18].
  • Scleraxis's cell component is recorded as transcription regulator complex[19].
  • Scleraxis's cell component is recorded as nucleus[20].
  • Scleraxis's biological process is recorded as cellular response to transforming growth factor beta stimulus[21].
  • Scleraxis's biological process is recorded as positive regulation of collagen biosynthetic process[22].
  • Scleraxis's biological process is recorded as cell differentiation[23].
  • Scleraxis's biological process is recorded as regulation of transcription, DNA-templated[24].
  • Scleraxis's biological process is recorded as chondrocyte differentiation[25].
  • Scleraxis's biological process is recorded as regulation of cartilage development[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . wikidata.org.
  6. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . Q20641742. Retrieved . wikidata.org.
  8. [9] . Q20641742. Retrieved . wikidata.org.
  9. [10] . Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . Scleraxis messenger ribonucleic acid is expressed in C2C12 myoblasts and its level is down-regulated by bone morphogenetic protein-2 (BMP2). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Scleraxis messenger ribonucleic acid is expressed in C2C12 myoblasts and its level is down-regulated by bone morphogenetic protein-2 (BMP2). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Scleraxis. Retrieved May 3, 2026, from https://4ort.xyz/entity/scleraxis
MLA “Scleraxis.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/scleraxis.
BibTeX @misc{4ortxyz_scleraxis_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Scleraxis}}, year = {2026}, url = {https://4ort.xyz/entity/scleraxis}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Scleraxis — https://4ort.xyz/entity/scleraxis (retrieved 2026-05-03)

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