RuvB like AAA ATPase 1

mammalian protein found in Homo sapiens
Protein protein Q7383575
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Summary

RuvB like AAA ATPase 1 is a protein[1]. It is known by 18 alternative names across languages and contexts.[2]

Key Facts

  • Part of: P-loop containing nucleoside triphosphate hydrolase[3], RuvB-like helicase 1[4], AAA proteins[5], TIP49, P-loop domain, protein family[6]
  • Has part(s): TIP49, P-loop domain[7], AAA+ ATPase domain[8]
  • Molecular function: nucleotide binding[9], 5'-3' DNA helicase activity[10], helicase activity[11], DNA helicase activity[12], ATPase activity[13], protein binding[14], hydrolase activity[15], ATP binding[16], cadherin binding[17], TFIID-class transcription factor complex binding[18], ADP binding[19], ATPase binding[20]
  • Cell component: membrane[21], nuclear matrix[22], NuA4 histone acetyltransferase complex[23], nucleoplasm[24], microtubule organizing center[25], MLL1 complex[26], extracellular exosome[27], cytoskeleton[28], nucleus[29], Swr1 complex[30], R2TP complex[31], cytoplasm[32], cytosol[33], Ino80 complex[34]
  • Biological process: DNA recombination[35], regulation of transcription, DNA-templated[36], positive regulation of protein targeting to mitochondrion[37], histone H2A acetylation[38], regulation of transcription by RNA polymerase II[39], CENP-A containing chromatin assembly[40], transcription, DNA-templated[41], cellular response to DNA damage stimulus[42], cell division[43], regulation of autophagy of mitochondrion[44], spermatogenesis[45], positive regulation of telomerase RNA localization to Cajal body[46], histone H4 acetylation[47], cell cycle[48]
  • Encoded by: RUVBL1[49]
  • Found in taxon: Homo sapiens[50]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . ANP32E is a histone chaperone that removes H2A.Z from chromatin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex Component RUVBL1 Is Required for the Functional Role of ECD in Cell Cycle Progression. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [37] ↑ . Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  36. [38] ↑ . Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  37. [39] ↑ . Identification and characterization of the ubiquitously occurring nuclear matrix protein NMP 238. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  38. [40] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  39. [41] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  40. [42] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  41. [43] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  42. [44] ↑ . Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  43. [45] ↑ . TIP49, homologous to the bacterial DNA helicase RuvB, acts as an autoantigen in human. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  44. [46] ↑ . Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  45. [47] ↑ . Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  46. [48] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  47. [49] ↑ . UniProt. Retrieved . wikidata.org.
  48. [50] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). RuvB like AAA ATPase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/ruvb-like-aaa-atpase-1-q7383575
MLA “RuvB like AAA ATPase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ruvb-like-aaa-atpase-1-q7383575.
BibTeX @misc{4ortxyz_ruvb-like-aaa-atpase-1-q7383575_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{RuvB like AAA ATPase 1}}, year = {2026}, url = {https://4ort.xyz/entity/ruvb-like-aaa-atpase-1-q7383575}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 11w ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Uniprot protein id → Q9Y265
    Ec enzyme number → 3.6.4.12
    Refseq protein id → NP_001306013, NP_001306015, NP_003698 +5
    Imported from → —
    + 12 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 3.6.4.12, [[:toollabs:quickstatements/#/batch/261457|batch #261457]]"
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