RNA polymerase II subunit D

mammalian protein found in Homo sapiens

Protein protein Q21123389

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RNA polymerase II subunit D

Summary

RNA polymerase II subunit D is a protein^[1].

Key Facts

RNA polymerase II subunit D's instance of is recorded as protein^[2].
RNA polymerase II subunit D's UniProt protein ID is recorded as O15514^[3].
RNA polymerase II subunit D's part of is recorded as RNA polymerase subunit RPB4/RPC9^[4].
RNA polymerase II subunit D's part of is recorded as HRDC-like superfamily^[5].
RNA polymerase II subunit D's part of is recorded as Rpb4/RPC9 superfamily^[6].
RNA polymerase II subunit D's part of is recorded as RNA polymerase Rpb4/RPC9, core domain, protein family^[7].
RNA polymerase II subunit D's has part is recorded as RNA polymerase Rpb4/RPC9, core^[8].
RNA polymerase II subunit D's RefSeq protein ID is recorded as NP_004796^[9].
RNA polymerase II subunit D's PDB structure ID is recorded as 2C35^[10].
RNA polymerase II subunit D's PDB structure ID is recorded as 5IYD^[11].
RNA polymerase II subunit D's PDB structure ID is recorded as 5IY8^[12].
RNA polymerase II subunit D's PDB structure ID is recorded as 5IYC^[13].
RNA polymerase II subunit D's PDB structure ID is recorded as 5IY6^[14].
RNA polymerase II subunit D's PDB structure ID is recorded as 5IY7^[15].
RNA polymerase II subunit D's PDB structure ID is recorded as 5IYA^[16].
RNA polymerase II subunit D's PDB structure ID is recorded as 5IY9^[17].
RNA polymerase II subunit D's PDB structure ID is recorded as 5IYB^[18].
RNA polymerase II subunit D's molecular function is recorded as nucleotide binding^[19].
RNA polymerase II subunit D's molecular function is recorded as DNA-directed 5'-3' RNA polymerase activity^[20].
RNA polymerase II subunit D's molecular function is recorded as single-stranded DNA binding^[21].
RNA polymerase II subunit D's molecular function is recorded as catalytic activity^[22].
RNA polymerase II subunit D's molecular function is recorded as single-stranded RNA binding^[23].
RNA polymerase II subunit D's molecular function is recorded as translation initiation factor binding^[24].
RNA polymerase II subunit D's molecular function is recorded as DNA-directed 5'-3' RNA polymerase activity^[25].
RNA polymerase II subunit D's cell component is recorded as P-body^[26].

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Quick Facts

Instance of protein

Part of RNA polymerase subunit RPB4/RPC9, HRDC-like superfamily, Rpb4/RPC9 superfamily, RNA polymerase Rpb4/RPC9, core domain, protein family

Properties

Biological process mRNA splicing, via spliceosome, recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex, transcription elongation from RNA polymerase II promoter, 7-methylguanosine mRNA capping, transcription by RNA polymerase II, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, cell metabolism, transcription-coupled nucleotide-excision repair, transcription initiation from RNA polymerase II promoter, positive regulation of translational initiation, mRNA export from nucleus in response to heat stress, fibroblast growth factor receptor signaling pathway, snRNA transcription by RNA polymerase II, RNA metabolic process, regulation of gene silencing by miRNA, DNA-templated transcription, initiation, transcription, DNA-templated, somatic stem cell population maintenance, positive regulation of viral transcription

Cell component P-body, RNA polymerase II, core complex, nucleus, nucleoplasm, cytosol, nuclear speck, nuclear DNA-directed RNA polymerase complex, RNA polymerase complex, RNA polymerase II, core complex

Encoded by POLR2D

Found in taxon Homo sapiens

Has part(s) RNA polymerase Rpb4/RPC9, core

Imported from wholeness_audit_2026-05-02

Molecular function nucleotide binding, DNA-directed 5'-3' RNA polymerase activity, single-stranded DNA binding, catalytic activity, single-stranded RNA binding, translation initiation factor binding, DNA-directed 5'-3' RNA polymerase activity

External References (4)

Ensembl protein id ENSP00000272645, ENSP00000387117, ENSP00000387323

Pdb structure id 2C35, 5IYD, 5IY8, 5IYC, 5IY6, 5IY7, 5IYA, 5IY9, 5IYB

Refseq protein id NP_004796

Uniprot protein id O15514

🏷️ Also known as

en DNA-directed RNA polymerase II 16 kDa polypeptide en DNA-directed RNA polymerase II subunit D en DNA-directed RNA polymerase II subunit RPB4 en POLR2D en polymerase (RNA) II (DNA directed) polypeptide D en polymerase (RNA) II subunit D en RNA polymerase II 16 kDa subunit en RNA polymerase II subunit B4 en RNA polymerase II subunit D en RNA polymerase II subunit hsRBP4 en RNA polymerase II subunit hsRPB4 en RPB16

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ RNA polymerase II subunit D — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ RNA polymerase II subunit D — UniProt protein ID (P352): O15514. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ RNA polymerase II subunit D — part of (P361): RNA polymerase subunit RPB4/RPC9. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ RNA polymerase II subunit D — part of (P361): HRDC-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ RNA polymerase II subunit D — part of (P361): Rpb4/RPC9 superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ RNA polymerase II subunit D — part of (P361): RNA polymerase Rpb4/RPC9, core domain, protein family. wikidata.org.
[8] ↑ RNA polymerase II subunit D — has part(s) (P527): RNA polymerase Rpb4/RPC9, core. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ RNA polymerase II subunit D — RefSeq protein ID (P637): NP_004796. Q20641742. Retrieved 2020-05-30. wikidata.org.
[10] ↑ RNA polymerase II subunit D — PDB structure ID (P638): 2C35. Q905695. Retrieved 2016-08-04. wikidata.org.
[11] ↑ RNA polymerase II subunit D — PDB structure ID (P638): 5IYD. Q905695. Retrieved 2016-08-04. wikidata.org.
[12] ↑ RNA polymerase II subunit D — PDB structure ID (P638): 5IY8. Q905695. Retrieved 2016-08-04. wikidata.org.
[13] ↑ RNA polymerase II subunit D — PDB structure ID (P638): 5IYC. Q905695. Retrieved 2016-08-04. wikidata.org.
[14] ↑ RNA polymerase II subunit D — PDB structure ID (P638): 5IY6. Q905695. Retrieved 2016-08-04. wikidata.org.
[15] ↑ RNA polymerase II subunit D — PDB structure ID (P638): 5IY7. Q905695. Retrieved 2016-08-04. wikidata.org.
[16] ↑ RNA polymerase II subunit D — PDB structure ID (P638): 5IYA. Q905695. Retrieved 2016-08-04. wikidata.org.
[17] ↑ RNA polymerase II subunit D — PDB structure ID (P638): 5IY9. Q905695. Retrieved 2016-08-04. wikidata.org.
[18] ↑ RNA polymerase II subunit D — PDB structure ID (P638): 5IYB. Q905695. Retrieved 2016-08-04. wikidata.org.
[19] ↑ RNA polymerase II subunit D — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ RNA polymerase II subunit D — molecular function (P680): DNA-directed 5'-3' RNA polymerase activity. Analysis of the Interaction of the Novel RNA Polymerase II (pol II) Subunit hsRPB4 with Its Partner hsRPB7 and with pol II. Retrieved 2018-06-21. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ RNA polymerase II subunit D — molecular function (P680): single-stranded DNA binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ RNA polymerase II subunit D — molecular function (P680): catalytic activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ RNA polymerase II subunit D — molecular function (P680): single-stranded RNA binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ RNA polymerase II subunit D — molecular function (P680): translation initiation factor binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ RNA polymerase II subunit D — molecular function (P680): DNA-directed 5'-3' RNA polymerase activity. Analysis of the Interaction of the Novel RNA Polymerase II (pol II) Subunit hsRPB4 with Its Partner hsRPB7 and with pol II. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ RNA polymerase II subunit D — cell component (P681): P-body. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ RNA polymerase II subunit D is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). RNA polymerase II subunit D. Retrieved May 3, 2026, from https://4ort.xyz/entity/rna-polymerase-ii-subunit-d

MLA

“RNA polymerase II subunit D.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/rna-polymerase-ii-subunit-d.

BibTeX

@misc{4ortxyz_rna-polymerase-ii-subunit-d_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{RNA polymerase II subunit D}}, year = {2026}, url = {https://4ort.xyz/entity/rna-polymerase-ii-subunit-d}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): RNA polymerase II subunit D — https://4ort.xyz/entity/rna-polymerase-ii-subunit-d (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/rna-polymerase-ii-subunit-d · Last refreshed: May 3, 2026