riociguat

chemical compound
ChemicalSubstance type_of_chemical_entity Q2154494
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riociguat

Summary

riociguat is a type of chemical entity[1]. riociguat has Wikipedia articles in 12 language editions, a strong signal of global cultural recognition.[2]

Key Facts

  • riociguat's instance of is recorded as type of chemical entity[3].
  • riociguat's physically interacts with is recorded as Guanylate cyclase 1 soluble subunit alpha 2[4].
  • riociguat's physically interacts with is recorded as Guanylate cyclase 1 soluble subunit beta 1[5].
  • riociguat's canonical SMILES is recorded as CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC[6].
  • riociguat's chemical formula is recorded as C₂₀H₁₉FN₈O₂[7].
  • riociguat is a type of chemical compound[8].
  • riociguat is used for medication[9].
  • riociguat's Commons category is recorded as Riociguat[10].
  • riociguat's significant drug interaction is recorded as vardenafil[11].
  • riociguat's significant drug interaction is recorded as sildenafil[12].
  • riociguat's significant drug interaction is recorded as tadalafil[13].
  • riociguat's significant drug interaction is recorded as nitroglycerin[14].
  • riociguat's significant drug interaction is recorded as isosorbide[15].
  • riociguat's significant drug interaction is recorded as isosorbide dinitrate[16].
  • riociguat's significant drug interaction is recorded as avanafil[17].
  • riociguat's mass is recorded as {'unit': 'Q483261', 'amount': '+422.1615'}[18].
  • riociguat's medical condition treated is recorded as pulmonary hypertension[19].
  • riociguat's medical condition treated is recorded as chronic pulmonary heart disease[20].
  • riociguat's medical condition treated is recorded as pulmonary hypertension[21].
  • riociguat's World Health Organisation international non-proprietary name is recorded as {'lang': 'en', 'text': 'riociguat'}[22].
  • riociguat's subject has role is recorded as enzyme activator[23].
  • riociguat's pregnancy category is recorded as Australian pregnancy category X[24].
  • riociguat's pregnancy category is recorded as US pregnancy category X[25].
  • riociguat's legal status is recorded as boxed warning[26].
  • riociguat's active ingredient in is recorded as Adempas[27].

Why It Matters

riociguat has Wikipedia articles in 12 language editions, a strong signal of global cultural recognition.[2] riociguat is known by 6 alternative names across languages and contexts.[28]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . wikidata.org.
  2. [4] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  3. [5] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  4. [6] . PubChem. Retrieved . wikidata.org.
  5. [7] . PubChem. Retrieved . wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . wikidata.org.
  9. [11] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  10. [12] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  11. [13] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  12. [14] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  13. [15] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  14. [16] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  15. [17] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  16. [18] . PubChem. Retrieved . wikidata.org.
  17. [19] . Drug Indications Extracted from FAERS. Retrieved . wikidata.org.
  18. [20] . Drug Indications Extracted from FAERS. Retrieved . wikidata.org.
  19. [21] . Inxight: Drugs Database. Retrieved . drugs.ncats.io. Provenance: wikidata.org.
  20. [22] . ChEBI. Retrieved . wikidata.org.
  21. [23] . Medical Subject Headings. Retrieved . wikidata.org.
  22. [24] . wikidata.org.
  23. [25] . wikidata.org.
  24. [26] . nctr-crs.fda.gov. nctr-crs.fda.gov. Provenance: wikidata.org.
  25. [27] . RxNorm. Retrieved . wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikidata sitelinks. wikidata.org.
  2. [28] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). riociguat. Retrieved May 3, 2026, from https://4ort.xyz/entity/riociguat
MLA “riociguat.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/riociguat.
BibTeX @misc{4ortxyz_riociguat_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{riociguat}}, year = {2026}, url = {https://4ort.xyz/entity/riociguat}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): riociguat — https://4ort.xyz/entity/riociguat (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/riociguat · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 21d ago · FlocciNivis · 2026-06-25 view diff on Wikidata ↗
    Pdb ligand id GZO
    "/* wbcreateclaim-create:1| */ [[Property:P3636]]: GZO, [[:toollabs:quickstatements/#/batch/259826|batch #259826]]"
  2. 27d ago · Nabbegat · 2026-06-19 view diff on Wikidata ↗
    Defined daily dose {'unit': 'Q3241121', 'amount': '+4.5'}
    Legal status (medicine) boxed warning
    Instance of type of chemical entity
    Has use medication
    + 12 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||tr */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/37300|batch #37300]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.