Ring finger protein 4

mammalian protein found in Homo sapiens
Protein protein Q21174948
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Summary

Ring finger protein 4 is a protein[1]. It is known by 7 alternative names across languages and contexts.[2]

Key Facts

  • Subclass of: protein[3]
  • Part of: Zinc finger, RING/FYVE/PHD-type[4], Zinc finger, RING-type, protein family[5], Zinc finger, RING-type, conserved site, protein family[6]
  • Has part(s): Zinc finger, RING-type, conserved site[7], Zinc finger, RING-type[8]
  • Molecular function: DNA binding[9], ubiquitin protein ligase activity[10], DNA-binding transcription factor activity[11], transcription coactivator activity[12], metal ion binding[13], ubiquitin-protein transferase activity[14], protein binding[15], androgen receptor binding[16], identical protein binding[17], nucleosome binding[18], transferase activity[19], transcription factor binding[20], SUMO polymer binding[21], zinc ion binding[22]
  • Cell component: cytoplasm[23], PML body[24], nucleoplasm[25], nucleus[26]
  • Biological process: androgen receptor signaling pathway[27], regulation of transcription, DNA-templated[28], protein K63-linked ubiquitination[29], response to arsenic-containing substance[30], transcription, DNA-templated[31], positive regulation of transcription, DNA-templated[32], protein K11-linked ubiquitination[33], regulation of kinetochore assembly[34], protein K48-linked ubiquitination[35], protein K6-linked ubiquitination[36], protein ubiquitination[37], regulation of spindle assembly[38], positive regulation of transcription by RNA polymerase II[39], proteasome-mediated ubiquitin-dependent protein catabolic process[40]
  • Encoded by: RNF4[41]
  • Found in taxon: Homo sapiens[42]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . UniProt. Retrieved . wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . Identification of a Novel RING Finger Protein as a Coregulator in Steroid Receptor-Mediated Gene Transcription. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . Negative modulation of androgen receptor transcriptional activity by Daxx. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Negative modulation of androgen receptor transcriptional activity by Daxx. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Identification of a Novel RING Finger Protein as a Coregulator in Steroid Receptor-Mediated Gene Transcription. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . Negative modulation of androgen receptor transcriptional activity by Daxx. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . The SUMO protease SENP6 is essential for inner kinetochore assembly. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [37] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  36. [38] ↑ . The SUMO protease SENP6 is essential for inner kinetochore assembly. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  37. [39] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  38. [40] ↑ . Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  39. [41] ↑ . UniProt. Retrieved . wikidata.org.
  40. [42] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Ring finger protein 4. Retrieved May 3, 2026, from https://4ort.xyz/entity/ring-finger-protein-4-q21174948
MLA “Ring finger protein 4.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ring-finger-protein-4-q21174948.
BibTeX @misc{4ortxyz_ring-finger-protein-4-q21174948_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Ring finger protein 4}}, year = {2026}, url = {https://4ort.xyz/entity/ring-finger-protein-4-q21174948}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Subclass of → protein
    Wikidata description → mammalian protein found in Homo sapiens
    Encoded by → RNF4
    + 12 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 2.3.2.27, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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