Ribosomal protein S6 kinase A5

mammalian protein found in Homo sapiens

Protein protein Q21119244

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Ribosomal protein S6 kinase A5

Summary

Ribosomal protein S6 kinase A5 is a protein^[1].

Key Facts

Ribosomal protein S6 kinase A5's instance of is recorded as protein^[2].
Ribosomal protein S6 kinase A5 is part of ribosomal protein S6 kinase II^[3].
Ribosomal protein S6 kinase A5 is part of Protein kinase-like domain superfamily^[4].
Ribosomal protein S6 kinase A5 is part of Protein kinase, C-terminal domain, protein family^[5].
Ribosomal protein S6 kinase A5 is part of AGC-kinase, C-terminal domain, protein family^[6].
Ribosomal protein S6 kinase A5 is part of Protein kinase domain, protein family^[7].
Ribosomal protein S6 kinase A5 is part of Protein kinase, ATP binding site, protein family^[8].
Ribosomal protein S6 kinase A5 is part of Serine/threonine-protein kinase, active site, protein family^[9].
Ribosomal protein S6 kinase A5 comprises AGC-kinase, C-terminal^[10].
Ribosomal protein S6 kinase A5 comprises protein kinase, ATP binding site^[11].
Ribosomal protein S6 kinase A5 comprises protein kinase, C-terminal^[12].
Ribosomal protein S6 kinase A5 comprises protein kinase domain^[13].
Ribosomal protein S6 kinase A5 comprises serine/threonine-protein kinase, active site^[14].
Ribosomal protein S6 kinase A5's molecular function is recorded as transferase activity^[15].
Ribosomal protein S6 kinase A5's molecular function is recorded as protein kinase activity^[16].
Ribosomal protein S6 kinase A5's molecular function is recorded as nucleotide binding^[17].
Ribosomal protein S6 kinase A5's molecular function is recorded as metal ion binding^[18].
Ribosomal protein S6 kinase A5's molecular function is recorded as kinase activity^[19].
Ribosomal protein S6 kinase A5's molecular function is recorded as protein binding^[20].
Ribosomal protein S6 kinase A5's molecular function is recorded as ATP binding^[21].
Ribosomal protein S6 kinase A5's molecular function is recorded as magnesium ion binding^[22].
Ribosomal protein S6 kinase A5's molecular function is recorded as protein serine/threonine kinase activity^[23].
Ribosomal protein S6 kinase A5's molecular function is recorded as protein serine/threonine kinase activity^[24].
Ribosomal protein S6 kinase A5's molecular function is recorded as protein serine/threonine kinase activity^[25].
Ribosomal protein S6 kinase A5's cell component is recorded as cytoplasm^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of ribosomal protein S6 kinase II, Protein kinase-like domain superfamily, Protein kinase, C-terminal domain, protein family, AGC-kinase, C-terminal domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Serine/threonine-protein kinase, active site, protein family

Properties

Biological process intracellular signal transduction, regulation of transcription, DNA-templated, epidermal growth factor receptor signaling pathway, phosphorylation, stimulatory C-type lectin receptor signaling pathway, axon guidance, positive regulation of histone acetylation, interleukin-1-mediated signaling pathway, protein phosphorylation, positive regulation of CREB transcription factor activity, positive regulation of NF-kappaB transcription factor activity, inflammatory response, negative regulation of transcription, DNA-templated, negative regulation of cytokine production, positive regulation of transcription by RNA polymerase II, protein phosphorylation, intracellular signal transduction

Cell component cytoplasm, nucleoplasm, nucleus, nucleus, cytoplasm

Ec enzyme number 2.7.11.1

Encoded by RPS6KA5

Found in taxon Homo sapiens

Has part(s) AGC-kinase, C-terminal, protein kinase, ATP binding site, protein kinase, C-terminal, protein kinase domain, serine/threonine-protein kinase, active site

Molecular function transferase activity, protein kinase activity, nucleotide binding, metal ion binding, kinase activity, protein binding, ATP binding, magnesium ion binding, protein serine/threonine kinase activity, protein serine/threonine kinase activity, protein serine/threonine kinase activity

External References (4)

Ensembl protein id ENSP00000402787, ENSP00000442803, ENSP00000479667, ENSP00000450591, ENSP00000451305, ENSP00000451736, ENSP00000497354

Pdb structure id 1VZO, 3KN5, 3KN6

Refseq protein id NP_001309156, NP_001309157, NP_001309158, NP_001309159, NP_001309160, NP_001309161, NP_001309162, NP_001309163, NP_001309164, NP_001309165, NP_001309166, NP_001309167, NP_004746, NP_872198, XP_016877275

Uniprot protein id O75582

🏷️ Also known as

en 90 kDa ribosomal protein S6 kinase 5 en nuclear mitogen- and stress-activated protein kinase 1 en ribosomal protein S6 kinase, 90kDa, polypeptide 5 en Ribosomal protein S6 kinase A5 en ribosomal protein S6 kinase alpha-5 en RPS6KA5 en RSKL en RSK-like protein kinase en S6K-alpha-5

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Ribosomal protein S6 kinase A5 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Ribosomal protein S6 kinase A5 — part of (P361): ribosomal protein S6 kinase II. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[4] ↑ Ribosomal protein S6 kinase A5 — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Ribosomal protein S6 kinase A5 — part of (P361): Protein kinase, C-terminal domain, protein family. wikidata.org.
[6] ↑ Ribosomal protein S6 kinase A5 — part of (P361): AGC-kinase, C-terminal domain, protein family. wikidata.org.
[7] ↑ Ribosomal protein S6 kinase A5 — part of (P361): Protein kinase domain, protein family. wikidata.org.
[8] ↑ Ribosomal protein S6 kinase A5 — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[9] ↑ Ribosomal protein S6 kinase A5 — part of (P361): Serine/threonine-protein kinase, active site, protein family. wikidata.org.
[10] ↑ Ribosomal protein S6 kinase A5 — has part(s) (P527): AGC-kinase, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Ribosomal protein S6 kinase A5 — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Ribosomal protein S6 kinase A5 — has part(s) (P527): protein kinase, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Ribosomal protein S6 kinase A5 — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Ribosomal protein S6 kinase A5 — has part(s) (P527): serine/threonine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): transferase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): protein kinase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): metal ion binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): kinase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): protein binding. Specific phosphorylation of histone demethylase KDM3A determines target gene expression in response to heat shock. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): ATP binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): magnesium ion binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): protein serine/threonine kinase activity. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): protein serine/threonine kinase activity. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Ribosomal protein S6 kinase A5 — molecular function (P680): protein serine/threonine kinase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Ribosomal protein S6 kinase A5 — cell component (P681): cytoplasm. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Ribosomal protein S6 kinase A5 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Ribosomal protein S6 kinase A5. Retrieved May 3, 2026, from https://4ort.xyz/entity/ribosomal-protein-s6-kinase-a5

MLA

“Ribosomal protein S6 kinase A5.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ribosomal-protein-s6-kinase-a5.

BibTeX

@misc{4ortxyz_ribosomal-protein-s6-kinase-a5_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Ribosomal protein S6 kinase A5}}, year = {2026}, url = {https://4ort.xyz/entity/ribosomal-protein-s6-kinase-a5}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Ribosomal protein S6 kinase A5 — https://4ort.xyz/entity/ribosomal-protein-s6-kinase-a5 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/ribosomal-protein-s6-kinase-a5 · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

5w ago · Boghog · 2026-07-24 view diff on Wikidata ↗

Imported from → —

Encoded by → RPS6KA5

Wikidata description → mammalian protein found in Homo sapiens

Molecular function → transferase activity, protein kinase activity, nucleotide binding +8

+ 11 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.7.11.1, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"

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