Replication protein A2

mammalian protein found in Homo sapiens

Protein protein Q21115044

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Replication protein A2

Summary

Replication protein A2 is a protein^[1].

Key Facts

Replication protein A2's instance of is recorded as protein^[2].
Replication protein A2's UniProt protein ID is recorded as P15927^[3].
Replication protein A2's part of is recorded as Nucleic acid-binding, OB-fold^[4].
Replication protein A2's part of is recorded as Replication factor A protein 2^[5].
Replication protein A2's part of is recorded as Winged helix-like DNA-binding domain superfamily^[6].
Replication protein A2's part of is recorded as winged helix DNA-binding domain superfamily^[7].
Replication protein A2's part of is recorded as Replication protein A, C-terminal domain, protein family^[8].
Replication protein A2's has part is recorded as Replication protein A, C-terminal^[9].
Replication protein A2's RefSeq protein ID is recorded as NP_001273005^[10].
Replication protein A2's RefSeq protein ID is recorded as NP_001284487^[11].
Replication protein A2's RefSeq protein ID is recorded as NP_002937^[12].
Replication protein A2's RefSeq protein ID is recorded as NP_001342057^[13].
Replication protein A2's RefSeq protein ID is recorded as NP_001342058^[14].
Replication protein A2's RefSeq protein ID is recorded as XP_024304630^[15].
Replication protein A2's RefSeq protein ID is recorded as XP_024304632^[16].
Replication protein A2's PDB structure ID is recorded as 1DPU^[17].
Replication protein A2's PDB structure ID is recorded as 1L1O^[18].
Replication protein A2's PDB structure ID is recorded as 1QUQ^[19].
Replication protein A2's PDB structure ID is recorded as 1Z1D^[20].
Replication protein A2's PDB structure ID is recorded as 2PI2^[21].
Replication protein A2's PDB structure ID is recorded as 2PQA^[22].
Replication protein A2's PDB structure ID is recorded as 2Z6K^[23].
Replication protein A2's PDB structure ID is recorded as 3KDF^[24].
Replication protein A2's PDB structure ID is recorded as 4MQV^[25].
Replication protein A2's PDB structure ID is recorded as 4OU0^[26].

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Quick Facts

Instance of protein

Part of Nucleic acid-binding, OB-fold, Replication factor A protein 2, Winged helix-like DNA-binding domain superfamily, winged helix DNA-binding domain superfamily, Replication protein A, C-terminal domain, protein family

Properties

Biological process nucleotide-excision repair, DNA gap filling, DNA recombination, interstrand cross-link repair, regulation of double-strand break repair via homologous recombination, error-free translesion synthesis, G1 phase, error-prone translesion synthesis, cellular response to DNA damage stimulus, DNA replication, mitotic G1 DNA damage checkpoint signaling, regulation of DNA damage checkpoint, regulation of cellular response to heat, DNA mismatch repair, translesion synthesis, transcription-coupled nucleotide-excision repair, nucleotide-excision repair, DNA incision, base-excision repair, nucleotide-excision repair, nucleotide-excision repair, preincision complex stabilization, regulation of signal transduction by p53 class mediator, DNA repair, double-strand break repair via homologous recombination, nucleotide-excision repair, preincision complex assembly, nucleotide-excision repair, DNA incision, 5'-to lesion, nucleotide-excision repair, DNA incision, 3'-to lesion, protein localization to chromosome, telomere maintenance, telomere maintenance via semi-conservative replication, G1/S transition of mitotic cell cycle, telomere maintenance via recombination, double-strand break repair via homologous recombination, DNA replication, DNA topological change, DNA unwinding involved in DNA replication, base-excision repair, nucleotide-excision repair, DNA mismatch repair, mitotic recombination, telomere maintenance via telomerase, reciprocal meiotic recombination, heteroduplex formation, positive regulation of helicase activity, regulation of DNA damage checkpoint, DNA repair, DNA mismatch repair

Cell component site of double-strand break, PML body, nucleoplasm, telomere, DNA replication factor A complex, chromatin, nucleus, nuclear body, telomere, chromatin, condensed nuclear chromosome, nucleoplasm, DNA replication factor A complex, site of double-strand break, nucleus

Encoded by RPA2

Found in taxon Homo sapiens

Has part(s) Replication protein A, C-terminal

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, protein N-terminus binding, single-stranded DNA binding, damaged DNA binding, protein binding, enzyme binding, protein phosphatase binding, ubiquitin protein ligase binding, G-rich strand telomeric DNA binding, damaged DNA binding, double-stranded DNA binding, single-stranded DNA binding, protein binding, sequence-specific DNA binding, G-rich strand telomeric DNA binding

External References (4)

Ensembl protein id ENSP00000363015, ENSP00000363017, ENSP00000363021, ENSP00000387649, ENSP00000413541

Pdb structure id 1DPU, 1L1O, 1QUQ, 1Z1D, 2PI2, 2PQA, 2Z6K, 3KDF, 4MQV, 4OU0

Refseq protein id NP_001273005, NP_001284487, NP_002937, NP_001342057, NP_001342058, XP_024304630, XP_024304632

Uniprot protein id P15927

🏷️ Also known as

en replication factor A protein 2 en Replication protein A2 en replication protein A2, 32kDa en replication protein A 32 kDa subunit en replication protein A 34 kDa subunit en RF-A protein 2 en RPA2 en RP-A p34

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Replication protein A2 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Replication protein A2 — UniProt protein ID (P352): P15927. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Replication protein A2 — part of (P361): Nucleic acid-binding, OB-fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Replication protein A2 — part of (P361): Replication factor A protein 2. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Replication protein A2 — part of (P361): Winged helix-like DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Replication protein A2 — part of (P361): winged helix DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Replication protein A2 — part of (P361): Replication protein A, C-terminal domain, protein family. wikidata.org.
[9] ↑ Replication protein A2 — has part(s) (P527): Replication protein A, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Replication protein A2 — RefSeq protein ID (P637): NP_001273005. Q20641742. Retrieved 2020-05-30. wikidata.org.
[11] ↑ Replication protein A2 — RefSeq protein ID (P637): NP_001284487. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ Replication protein A2 — RefSeq protein ID (P637): NP_002937. Q20641742. Retrieved 2020-05-30. wikidata.org.
[13] ↑ Replication protein A2 — RefSeq protein ID (P637): NP_001342057. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ Replication protein A2 — RefSeq protein ID (P637): NP_001342058. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ Replication protein A2 — RefSeq protein ID (P637): XP_024304630. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ Replication protein A2 — RefSeq protein ID (P637): XP_024304632. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ Replication protein A2 — PDB structure ID (P638): 1DPU. Q905695. Retrieved 2016-08-09. wikidata.org.
[18] ↑ Replication protein A2 — PDB structure ID (P638): 1L1O. Q905695. Retrieved 2016-08-09. wikidata.org.
[19] ↑ Replication protein A2 — PDB structure ID (P638): 1QUQ. Q905695. Retrieved 2016-08-09. wikidata.org.
[20] ↑ Replication protein A2 — PDB structure ID (P638): 1Z1D. Q905695. Retrieved 2016-08-09. wikidata.org.
[21] ↑ Replication protein A2 — PDB structure ID (P638): 2PI2. Q905695. Retrieved 2016-08-09. wikidata.org.
[22] ↑ Replication protein A2 — PDB structure ID (P638): 2PQA. Q905695. Retrieved 2016-08-09. wikidata.org.
[23] ↑ Replication protein A2 — PDB structure ID (P638): 2Z6K. Q905695. Retrieved 2016-08-09. wikidata.org.
[24] ↑ Replication protein A2 — PDB structure ID (P638): 3KDF. Q905695. Retrieved 2016-08-09. wikidata.org.
[25] ↑ Replication protein A2 — PDB structure ID (P638): 4MQV. Q905695. Retrieved 2016-08-09. wikidata.org.
[26] ↑ Replication protein A2 — PDB structure ID (P638): 4OU0. Q905695. Retrieved 2016-08-09. wikidata.org.

Class ancestry

[1] ↑ Replication protein A2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Replication protein A2. Retrieved May 3, 2026, from https://4ort.xyz/entity/replication-protein-a2-q21115044

MLA

“Replication protein A2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/replication-protein-a2-q21115044.

BibTeX

@misc{4ortxyz_replication-protein-a2-q21115044_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Replication protein A2}}, year = {2026}, url = {https://4ort.xyz/entity/replication-protein-a2-q21115044}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Replication protein A2 — https://4ort.xyz/entity/replication-protein-a2-q21115044 (retrieved 2026-05-03)

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