Replication protein A1

mammalian protein found in Homo sapiens

Protein protein Q21109589

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Replication protein A1

Summary

Replication protein A1 is a protein^[1].

Key Facts

Replication protein A1's instance of is recorded as protein^[2].
Replication protein A1's UniProt protein ID is recorded as P27694^[3].
Replication protein A1's part of is recorded as Nucleic acid-binding, OB-fold^[4].
Replication protein A1's part of is recorded as Replication factor A protein 1^[5].
Replication protein A1's part of is recorded as Replication protein A, OB domain, protein family^[6].
Replication protein A1's part of is recorded as Replication factor-A protein 1, N-terminal domain, protein family^[7].
Replication protein A1's part of is recorded as Replication factor A, C-terminal domain, protein family^[8].
Replication protein A1's part of is recorded as OB-fold nucleic acid binding domain, AA-tRNA synthetase-type family^[9].
Replication protein A1's has part is recorded as Replication protein A, OB domain^[10].
Replication protein A1's has part is recorded as OB-fold nucleic acid binding domain, AA-tRNA synthetase-type^[11].
Replication protein A1's has part is recorded as Replication factor A, C-terminal^[12].
Replication protein A1's has part is recorded as Replication factor-A protein 1, N-terminal^[13].
Replication protein A1's RefSeq protein ID is recorded as NP_002936^[14].
Replication protein A1's RefSeq protein ID is recorded as NP_001342049^[15].
Replication protein A1's RefSeq protein ID is recorded as NP_001342050^[16].
Replication protein A1's RefSeq protein ID is recorded as XP_024306631^[17].
Replication protein A1's PDB structure ID is recorded as 1EWI^[18].
Replication protein A1's PDB structure ID is recorded as 1FGU^[19].
Replication protein A1's PDB structure ID is recorded as 1JMC^[20].
Replication protein A1's PDB structure ID is recorded as 1L1O^[21].
Replication protein A1's PDB structure ID is recorded as 2B29^[22].
Replication protein A1's PDB structure ID is recorded as 2B3G^[23].
Replication protein A1's PDB structure ID is recorded as 4IJH^[24].
Replication protein A1's PDB structure ID is recorded as 4IJL^[25].
Replication protein A1's PDB structure ID is recorded as 4IPC^[26].

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Quick Facts

Instance of protein

Part of Nucleic acid-binding, OB-fold, Replication factor A protein 1, Replication protein A, OB domain, protein family, Replication factor-A protein 1, N-terminal domain, protein family, Replication factor A, C-terminal domain, protein family, OB-fold nucleic acid binding domain, AA-tRNA synthetase-type family

Properties

Biological process DNA-dependent DNA replication, nucleotide-excision repair, DNA gap filling, DNA recombination, interstrand cross-link repair, error-free translesion synthesis, G1 phase, error-prone translesion synthesis, cellular response to DNA damage stimulus, DNA replication, regulation of cellular response to heat, DNA mismatch repair, translesion synthesis, transcription-coupled nucleotide-excision repair, nucleotide-excision repair, DNA incision, nucleotide-excision repair, DNA incision, 3'-to lesion, nucleotide-excision repair, DNA incision, 5'-to lesion, nucleotide-excision repair, preincision complex stabilization, nucleotide-excision repair, DNA repair, base-excision repair, regulation of signal transduction by p53 class mediator, double-strand break repair via homologous recombination, nucleotide-excision repair, preincision complex assembly, protein localization to chromosome, telomere maintenance, telomere maintenance via semi-conservative replication, G1/S transition of mitotic cell cycle, telomere maintenance, double-strand break repair via homologous recombination, DNA-dependent DNA replication, DNA unwinding involved in DNA replication, DNA repair, nucleotide-excision repair, DNA mismatch repair, cellular response to DNA damage stimulus, telomere maintenance via telomerase, meiosis

Cell component PML body, nucleoplasm, DNA replication factor A complex, nucleus, DNA replication factor A complex, site of DNA damage

Encoded by RPA1

Exact match identifiers.org, purl.uniprot.org, www.ncbi.nlm.nih.gov

Found in taxon Homo sapiens

Has part(s) Replication protein A, OB domain, OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, Replication factor A, C-terminal, Replication factor-A protein 1, N-terminal

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, metal ion binding, single-stranded DNA binding, damaged DNA binding, protein binding, nucleic acid binding, G-rich strand telomeric DNA binding, damaged DNA binding, single-stranded DNA binding, single-stranded telomeric DNA binding, sequence-specific DNA binding

External References (4)

Ensembl protein id ENSP00000254719, ENSP00000459788, ENSP00000461466, ENSP00000461733

Pdb structure id 1EWI, 1FGU, 1JMC, 1L1O, 2B29, 2B3G, 4IJH, 4IJL, 4IPC, 4IPD, 4IPG, 4IPH, 4LUO, 4LUV, 4LUZ, 4LW1, 4LWC, 4NB3, 4O0A, 4R4C, 4R4I, 4R4O, 4R4Q, 4R4T, 5E7N, 5EAY

Refseq protein id NP_002936, NP_001342049, NP_001342050, XP_024306631

Uniprot protein id P27694

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Replication protein A1 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Replication protein A1 — UniProt protein ID (P352): P27694. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Replication protein A1 — part of (P361): Nucleic acid-binding, OB-fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Replication protein A1 — part of (P361): Replication factor A protein 1. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Replication protein A1 — part of (P361): Replication protein A, OB domain, protein family. wikidata.org.
[7] ↑ Replication protein A1 — part of (P361): Replication factor-A protein 1, N-terminal domain, protein family. wikidata.org.
[8] ↑ Replication protein A1 — part of (P361): Replication factor A, C-terminal domain, protein family. wikidata.org.
[9] ↑ Replication protein A1 — part of (P361): OB-fold nucleic acid binding domain, AA-tRNA synthetase-type family. wikidata.org.
[10] ↑ Replication protein A1 — has part(s) (P527): Replication protein A, OB domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Replication protein A1 — has part(s) (P527): OB-fold nucleic acid binding domain, AA-tRNA synthetase-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Replication protein A1 — has part(s) (P527): Replication factor A, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Replication protein A1 — has part(s) (P527): Replication factor-A protein 1, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Replication protein A1 — RefSeq protein ID (P637): NP_002936. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ Replication protein A1 — RefSeq protein ID (P637): NP_001342049. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ Replication protein A1 — RefSeq protein ID (P637): NP_001342050. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ Replication protein A1 — RefSeq protein ID (P637): XP_024306631. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ Replication protein A1 — PDB structure ID (P638): 1EWI. Q905695. Retrieved 2016-08-04. wikidata.org.
[19] ↑ Replication protein A1 — PDB structure ID (P638): 1FGU. Q905695. Retrieved 2016-08-04. wikidata.org.
[20] ↑ Replication protein A1 — PDB structure ID (P638): 1JMC. Q905695. Retrieved 2016-08-04. wikidata.org.
[21] ↑ Replication protein A1 — PDB structure ID (P638): 1L1O. Q905695. Retrieved 2016-08-04. wikidata.org.
[22] ↑ Replication protein A1 — PDB structure ID (P638): 2B29. Q905695. Retrieved 2016-08-04. wikidata.org.
[23] ↑ Replication protein A1 — PDB structure ID (P638): 2B3G. Q905695. Retrieved 2016-08-04. wikidata.org.
[24] ↑ Replication protein A1 — PDB structure ID (P638): 4IJH. Q905695. Retrieved 2016-08-04. wikidata.org.
[25] ↑ Replication protein A1 — PDB structure ID (P638): 4IJL. Q905695. Retrieved 2016-08-04. wikidata.org.
[26] ↑ Replication protein A1 — PDB structure ID (P638): 4IPC. Q905695. Retrieved 2016-08-04. wikidata.org.

Class ancestry

[1] ↑ Replication protein A1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Replication protein A1. Retrieved May 3, 2026, from https://4ort.xyz/entity/replication-protein-a1

MLA

“Replication protein A1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/replication-protein-a1.

BibTeX

@misc{4ortxyz_replication-protein-a1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Replication protein A1}}, year = {2026}, url = {https://4ort.xyz/entity/replication-protein-a1}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Replication protein A1 — https://4ort.xyz/entity/replication-protein-a1 (retrieved 2026-05-03)

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