RELA proto-oncogene, NF-kB subunit

mammalian protein found in Rattus norvegicus

Protein protein Q29519167

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RELA proto-oncogene, NF-kB subunit

Summary

RELA proto-oncogene, NF-kB subunit is a protein^[1].

Key Facts

RELA proto-oncogene, NF-kB subunit's instance of is recorded as protein^[2].
RELA proto-oncogene, NF-kB subunit's UniProt protein ID is recorded as Q7TQN4^[3].
RELA proto-oncogene, NF-kB subunit's part of is recorded as p53-like transcription factor, DNA-binding^[4].
RELA proto-oncogene, NF-kB subunit's part of is recorded as Immunoglobulin-like fold^[5].
RELA proto-oncogene, NF-kB subunit's part of is recorded as transcription factor RelA (p65)^[6].
RELA proto-oncogene, NF-kB subunit's part of is recorded as Immunoglobulin E-set^[7].
RELA proto-oncogene, NF-kB subunit's part of is recorded as Rel homology domain (RHD), DNA-binding domain superfamily^[8].
RELA proto-oncogene, NF-kB subunit's part of is recorded as IPT domain, protein family^[9].
RELA proto-oncogene, NF-kB subunit's part of is recorded as Rel homology dimerisation domain, protein family^[10].
RELA proto-oncogene, NF-kB subunit's part of is recorded as Rel homology domain (RHD), DNA-binding domain, protein family^[11].
RELA proto-oncogene, NF-kB subunit's part of is recorded as NFkappaB IPT domain, protein family^[12].
RELA proto-oncogene, NF-kB subunit's part of is recorded as Rel homology domain, conserved site, protein family^[13].
RELA proto-oncogene, NF-kB subunit's has part is recorded as Rel homology domain (RHD), DNA-binding domain^[14].
RELA proto-oncogene, NF-kB subunit's has part is recorded as Rel homology dimerisation domain^[15].
RELA proto-oncogene, NF-kB subunit's has part is recorded as NFkappaB IPT domain^[16].
RELA proto-oncogene, NF-kB subunit's has part is recorded as IPT domain^[17].
RELA proto-oncogene, NF-kB subunit's has part is recorded as Rel homology domain, conserved site^[18].
RELA proto-oncogene, NF-kB subunit's RefSeq protein ID is recorded as NP_954888^[19].
RELA proto-oncogene, NF-kB subunit's RefSeq protein ID is recorded as XP_038935449^[20].
RELA proto-oncogene, NF-kB subunit's molecular function is recorded as RNA polymerase II transcription regulatory region sequence-specific DNA binding^[21].
RELA proto-oncogene, NF-kB subunit's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding^[22].
RELA proto-oncogene, NF-kB subunit's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding^[23].
RELA proto-oncogene, NF-kB subunit's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific^[24].
RELA proto-oncogene, NF-kB subunit's molecular function is recorded as DNA-binding transcription repressor activity, RNA polymerase II-specific^[25].
RELA proto-oncogene, NF-kB subunit's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[26].

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Quick Facts

Instance of protein

Part of p53-like transcription factor, DNA-binding, Immunoglobulin-like fold, transcription factor RelA (p65), Immunoglobulin E-set, Rel homology domain (RHD), DNA-binding domain superfamily, IPT domain, protein family, Rel homology dimerisation domain, protein family, Rel homology domain (RHD), DNA-binding domain, protein family, NFkappaB IPT domain, protein family, Rel homology domain, conserved site, protein family

Properties

Biological process negative regulation of transcription by RNA polymerase II, liver development, hair follicle development, acetaldehyde metabolic process, chromatin organization, transcription, DNA-templated, regulation of transcription, DNA-templated, defense response, inflammatory response, I-kappaB kinase/NF-kappaB signaling, ageing, positive regulation of cell population proliferation, response to mechanical stimulus, response to bacterium, animal organ morphogenesis, response to organic substance, response to inorganic substance, response to UV-B, positive regulation of Schwann cell differentiation, response to organic cyclic compound, cytokine-mediated signaling pathway, positive regulation of chondrocyte differentiation, response to muramyl dipeptide, response to lipopolysaccharide, response to progesterone, response to insulin, tumor necrosis factor-mediated signaling pathway, negative regulation of protein sumoylation, response to cobalamin, response to cytokine, cellular response to hepatocyte growth factor stimulus, cellular response to vascular endothelial growth factor stimulus, response to muscle stretch, NIK/NF-kappaB signaling, negative regulation of protein catabolic process, response to hydrogen peroxide, negative regulation of apoptotic process, positive regulation of I-kappaB kinase/NF-kappaB signaling, response to amino acid, response to morphine, regulation of DNA-templated transcription in response to stress, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, negative regulation of insulin receptor signaling pathway, regulation of inflammatory response, positive regulation of T cell receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, response to cAMP, pri-miRNA transcription by RNA polymerase II, cellular response to hydrogen peroxide, nucleotide-binding oligomerization domain containing 2 signaling pathway, response to interleukin-1, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, cellular response to peptidoglycan, cellular response to nicotine, cellular response to interleukin-1, cellular response to interleukin-6, cellular response to tumor necrosis factor, postsynapse to nucleus signaling pathway, regulation of NIK/NF-kappaB signaling, negative regulation of NIK/NF-kappaB signaling, positive regulation of NIK/NF-kappaB signaling, positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus, negative regulation of pri-miRNA transcription by RNA polymerase II, positive regulation of pri-miRNA transcription by RNA polymerase II, cellular response to angiotensin, positive regulation of leukocyte adhesion to vascular endothelial cell, positive regulation of miRNA metabolic process, negative regulation of extrinsic apoptotic signaling pathway

Cell component nucleus, nucleoplasm, transcription regulator complex, cytoplasm, cytosol, protein-containing complex, NF-kappaB p50/p65 complex, synapse, NF-kappaB complex, glutamatergic synapse

Encoded by Rela

Found in taxon brown rat

Has part(s) Rel homology domain (RHD), DNA-binding domain, Rel homology dimerisation domain, NFkappaB IPT domain, IPT domain, Rel homology domain, conserved site

Imported from wholeness_audit_2026-05-02

Molecular function RNA polymerase II transcription regulatory region sequence-specific DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA binding, chromatin binding, DNA-binding transcription factor activity, protein binding, transcription factor binding, enzyme binding, protein kinase binding, chromatin DNA binding, ubiquitin protein ligase binding, phosphate ion binding, identical protein binding, protein homodimerization activity, actinin binding, histone deacetylase binding, sequence-specific DNA binding, protein-containing complex binding, protein heterodimerization activity, protein N-terminus binding, NF-kappaB binding, ankyrin repeat binding

External References (2)

Refseq protein id NP_954888, XP_038935449

Uniprot protein id Q7TQN4

🏷️ Also known as

en nuclear factor kappa B subunit p65 en nuclear factor kappaB subunit p65 en Rela en RELA proto-oncogene, NF-kB subunit en transcription factor p65 en v-rel avian reticuloendotheliosis viral oncogene homolog A en v-rel reticuloendotheliosis viral oncogene homolog A

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ RELA proto-oncogene, NF-kB subunit — instance of (P31): protein. Q905695. Retrieved 2021-11-17. wikidata.org.
[3] ↑ RELA proto-oncogene, NF-kB subunit — UniProt protein ID (P352): Q7TQN4. Q905695. Retrieved 2021-11-17. wikidata.org.
[4] ↑ RELA proto-oncogene, NF-kB subunit — part of (P361): p53-like transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ RELA proto-oncogene, NF-kB subunit — part of (P361): Immunoglobulin-like fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ RELA proto-oncogene, NF-kB subunit — part of (P361): transcription factor RelA (p65). InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ RELA proto-oncogene, NF-kB subunit — part of (P361): Immunoglobulin E-set. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ RELA proto-oncogene, NF-kB subunit — part of (P361): Rel homology domain (RHD), DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ RELA proto-oncogene, NF-kB subunit — part of (P361): IPT domain, protein family. wikidata.org.
[10] ↑ RELA proto-oncogene, NF-kB subunit — part of (P361): Rel homology dimerisation domain, protein family. wikidata.org.
[11] ↑ RELA proto-oncogene, NF-kB subunit — part of (P361): Rel homology domain (RHD), DNA-binding domain, protein family. wikidata.org.
[12] ↑ RELA proto-oncogene, NF-kB subunit — part of (P361): NFkappaB IPT domain, protein family. wikidata.org.
[13] ↑ RELA proto-oncogene, NF-kB subunit — part of (P361): Rel homology domain, conserved site, protein family. wikidata.org.
[14] ↑ RELA proto-oncogene, NF-kB subunit — has part(s) (P527): Rel homology domain (RHD), DNA-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ RELA proto-oncogene, NF-kB subunit — has part(s) (P527): Rel homology dimerisation domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ RELA proto-oncogene, NF-kB subunit — has part(s) (P527): NFkappaB IPT domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ RELA proto-oncogene, NF-kB subunit — has part(s) (P527): IPT domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ RELA proto-oncogene, NF-kB subunit — has part(s) (P527): Rel homology domain, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ RELA proto-oncogene, NF-kB subunit — RefSeq protein ID (P637): NP_954888. Q20641742. Retrieved 2021-09-07. wikidata.org.
[20] ↑ RELA proto-oncogene, NF-kB subunit — RefSeq protein ID (P637): XP_038935449. Q20641742. Retrieved 2021-09-07. wikidata.org.
[21] ↑ RELA proto-oncogene, NF-kB subunit — molecular function (P680): RNA polymerase II transcription regulatory region sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ RELA proto-oncogene, NF-kB subunit — molecular function (P680): RNA polymerase II cis-regulatory region sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ RELA proto-oncogene, NF-kB subunit — molecular function (P680): RNA polymerase II cis-regulatory region sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ RELA proto-oncogene, NF-kB subunit — molecular function (P680): DNA-binding transcription factor activity, RNA polymerase II-specific. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ RELA proto-oncogene, NF-kB subunit — molecular function (P680): DNA-binding transcription repressor activity, RNA polymerase II-specific. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ RELA proto-oncogene, NF-kB subunit — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ RELA proto-oncogene, NF-kB subunit is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). RELA proto-oncogene, NF-kB subunit. Retrieved May 3, 2026, from https://4ort.xyz/entity/rela-proto-oncogene-nf-kb-subunit

MLA

“RELA proto-oncogene, NF-kB subunit.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/rela-proto-oncogene-nf-kb-subunit.

BibTeX

@misc{4ortxyz_rela-proto-oncogene-nf-kb-subunit_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{RELA proto-oncogene, NF-kB subunit}}, year = {2026}, url = {https://4ort.xyz/entity/rela-proto-oncogene-nf-kb-subunit}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): RELA proto-oncogene, NF-kB subunit — https://4ort.xyz/entity/rela-proto-oncogene-nf-kb-subunit (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/rela-proto-oncogene-nf-kb-subunit · Last refreshed: May 3, 2026