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Receptor activity modifying protein 3

mammalian protein found in Homo sapiens
Protein protein Q7275754

Facts

9 properties
Instance of
protein
Part of
Receptor activity modifying protein, RAMP domain superfamily[3][4]
Biological process
G protein-coupled receptor signaling pathway, regulation of G protein-coupled receptor signaling pathway, cellular response to estradiol stimulus, receptor internalization, G protein-coupled receptor signaling pathway involved in heart process, transport, protein transport, protein localization to plasma membrane, intracellular protein transport, negative regulation of transcription, DNA-templated, calcium ion transport, positive regulation of receptor recycling, angiogenesis, calcium ion transport, G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, positive regulation of gene expression, positive regulation of protein kinase A signaling, positive regulation of cell death, protein transport, receptor internalization, cellular response to hormone stimulus, positive regulation of peptidyl-serine phosphorylation, cross-receptor inhibition within G protein-coupled receptor heterodimer, positive regulation of protein kinase B signaling, positive regulation of ERK1 and ERK2 cascade, protein localization to plasma membrane, amylin receptor signaling pathway, positive regulation of protein localization to plasma membrane, response to amyloid-beta, positive regulation of calcium ion import across plasma membrane, adrenomedullin receptor signaling pathway
Cell component
integral component of membrane, membrane, plasma membrane, receptor complex, integral component of plasma membrane, intracellular anatomical structure, cell surface, lysosome, cell surface, receptor complex, amylin receptor complex 3, adrenomedullin receptor complex[11][12][13][14][15][16][17][18]
Encoded by
RAMP3
Found in taxon
Homo sapiens
Imported from
wholeness_audit_2026-05-02
Molecular function
coreceptor activity, protein binding, amyloid-beta binding, adrenomedullin receptor activity, coreceptor activity, amylin receptor activity[5][6][7][8][9][10]
Physically interacts with
pramlintide[2]
🏷️ Also known as
en calcitonin receptor-like receptor activity modifying protein 3 en Calcitonin-receptor-like receptor activity-modifying protein 3 en CRLR activity-modifying protein 3 en RAMP3 en receptor activity-modifying protein 3 en Receptor activity modifying protein 3 en receptor (calcitonin) activity modifying protein 3 en receptor (G protein-coupled) activity modifying protein 3
🔖 Identifiers · 7
Ensembl protein ID
ENSP00000419012, ENSP00000242249, ENSP00000418460
MeSH descriptor ID
D058264
MeSH tree code
D12.776.476.024.414.300, D12.776.543.725.300
RefSeq protein ID
NP_005847, XP_006715694, XP_016867155
Transporter Classification Database ID
8.A.127.1.3
UMLS CUI
C3887979
UniProt protein ID
O60896

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Summary

Receptor activity modifying protein 3 is a protein[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  2. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [6] ↑ . Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [7] ↑ . Amyloid β (Aβ) Peptide Directly Activates Amylin-3 Receptor Subtype by Triggering Multiple Intracellular Signaling Pathways. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . Amyloid β (Aβ) Peptide Directly Activates Amylin-3 Receptor Subtype by Triggering Multiple Intracellular Signaling Pathways. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Receptor activity modifying protein 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/receptor-activity-modifying-protein-3
MLA “Receptor activity modifying protein 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/receptor-activity-modifying-protein-3.
BibTeX @misc{4ortxyz_receptor-activity-modifying-protein-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Receptor activity modifying protein 3}}, year = {2026}, url = {https://4ort.xyz/entity/receptor-activity-modifying-protein-3}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Receptor activity modifying protein 3 — https://4ort.xyz/entity/receptor-activity-modifying-protein-3 (retrieved 2026-05-03)

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