Home › Entities › protein › receptor activity modifying protein 2

receptor activity modifying protein 2

mammalian protein found in Homo sapiens
Protein protein Q7275753

Facts

9 properties
Instance of
protein
Part of
Receptor activity modifying protein, RAMP domain superfamily[3][4]
Biological process
negative regulation of endothelial cell apoptotic process, G protein-coupled receptor signaling pathway, response to estradiol, response to hypoxia, regulation of G protein-coupled receptor signaling pathway, adherens junction assembly, response to progesterone, female pregnancy, receptor internalization, sprouting angiogenesis, basement membrane assembly, positive regulation of angiogenesis, vasculogenesis, regulation of blood pressure, development of the heart, cellular response to hormone stimulus, positive regulation of gene expression, positive regulation of vasculogenesis, angiogenesis, bicellular tight junction assembly, transport, protein transport, cellular response to vascular endothelial growth factor stimulus, intracellular protein transport, protein localization to plasma membrane, vascular associated smooth muscle cell development, calcium ion transport, negative regulation of vascular permeability, cAMP biosynthetic process, angiogenesis, calcium ion transport, G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, protein transport, receptor internalization, cellular response to hormone stimulus, protein localization to plasma membrane, amylin receptor signaling pathway, adrenomedullin receptor signaling pathway
Cell component
cytoplasm, integral component of membrane, membrane, plasma membrane, receptor complex, integral component of plasma membrane, cell surface, clathrin-coated pit, lysosome, cell surface, receptor complex, amylin receptor complex 2, adrenomedullin receptor complex[11][12][13][14][15][16]
Encoded by
RAMP2
Found in taxon
Homo sapiens
Imported from
wholeness_audit_2026-05-02
Molecular function
coreceptor activity, protein binding, adrenomedullin receptor activity, coreceptor activity, amylin receptor activity, adrenomedullin binding[5][6][7][8][9][10]
Physically interacts with
pramlintide[2]
🏷️ Also known as
en calcitonin receptor-like receptor activity modifying protein 2 en Calcitonin-receptor-like receptor activity-modifying protein 2 en CRLR activity-modifying protein 2 en RAMP2 en receptor activity modifying protein 2 en receptor activity-modifying protein 2 en receptor (calcitonin) activity modifying protein 2 en receptor (G protein-coupled) activity modifying protein 2
🔖 Identifiers · 8
Ensembl protein ID
ENSP00000466455, ENSP00000253796, ENSP00000465725, ENSP00000466980, ENSP00000467463
MeSH descriptor ID
D058263
MeSH tree code
D12.776.476.024.414.200, D12.776.543.725.200
PDB structure ID
4RWF, 2XVT, 3AQE, 3AQF
RefSeq protein ID
NP_005845
Transporter Classification Database ID
8.A.127.1.2
UMLS CUI
C3887978
UniProt protein ID
O60895

Report an error or request removal Lineage (PROV-JSON)

Press Enter · cited answer in seconds

Summary

receptor activity modifying protein 2 is a protein[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  2. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [6] ↑ . RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [7] ↑ . Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . Amyloid β (Aβ) Peptide Directly Activates Amylin-3 Receptor Subtype by Triggering Multiple Intracellular Signaling Pathways. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). receptor activity modifying protein 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/receptor-activity-modifying-protein-2
MLA “receptor activity modifying protein 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/receptor-activity-modifying-protein-2.
BibTeX @misc{4ortxyz_receptor-activity-modifying-protein-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{receptor activity modifying protein 2}}, year = {2026}, url = {https://4ort.xyz/entity/receptor-activity-modifying-protein-2}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): receptor activity modifying protein 2 — https://4ort.xyz/entity/receptor-activity-modifying-protein-2 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/receptor-activity-modifying-protein-2 · Last refreshed: