RAS p21 protein activator 1

mammalian protein found in Homo sapiens

Protein protein Q21104745

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RAS p21 protein activator 1

Summary

RAS p21 protein activator 1 is a protein^[1].

Key Facts

RAS p21 protein activator 1's instance of is recorded as protein^[2].
RAS p21 protein activator 1's UniProt protein ID is recorded as P20936^[3].
RAS p21 protein activator 1's part of is recorded as SH3-like domain superfamily^[4].
RAS p21 protein activator 1's part of is recorded as C2 domain superfamily^[5].
RAS p21 protein activator 1's part of is recorded as SH2 domain superfamily^[6].
RAS p21 protein activator 1's part of is recorded as Ras GTPase-activating protein 1^[7].
RAS p21 protein activator 1's part of is recorded as Rho GTPase activation protein^[8].
RAS p21 protein activator 1's part of is recorded as PH-like domain superfamily^[9].
RAS p21 protein activator 1's part of is recorded as pleckstrin homology domain, protein family^[10].
RAS p21 protein activator 1's part of is recorded as RasGAP, SH3 domain, protein family^[11].
RAS p21 protein activator 1's part of is recorded as SH2 domain, protein family^[12].
RAS p21 protein activator 1's part of is recorded as Ras GTPase-activating protein 1, C-terminal SH2 domain, protein family^[13].
RAS p21 protein activator 1's part of is recorded as C2 domain, protein family^[14].
RAS p21 protein activator 1's part of is recorded as Ras GTPase-activating domain, protein family^[15].
RAS p21 protein activator 1's part of is recorded as Ras GTPase-activating protein 1, N-terminal SH2 domain, protein family^[16].
RAS p21 protein activator 1's part of is recorded as SH3 domain, protein family^[17].
RAS p21 protein activator 1's part of is recorded as Ras GTPase-activating protein, conserved site, protein family^[18].
RAS p21 protein activator 1's has part is recorded as SH3 domain^[19].
RAS p21 protein activator 1's has part is recorded as pleckstrin homology domain^[20].
RAS p21 protein activator 1's has part is recorded as SH2 domain^[21].
RAS p21 protein activator 1's has part is recorded as Ras GTPase-activating protein, conserved site^[22].
RAS p21 protein activator 1's has part is recorded as Ras GTPase-activating domain^[23].
RAS p21 protein activator 1's has part is recorded as C2 domain^[24].
RAS p21 protein activator 1's has part is recorded as RasGAP, SH3 domain^[25].
RAS p21 protein activator 1's has part is recorded as Ras GTPase-activating protein 1, N-terminal SH2 domain^[26].

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Quick Facts

Instance of protein

Part of SH3-like domain superfamily, C2 domain superfamily, SH2 domain superfamily, Ras GTPase-activating protein 1, Rho GTPase activation protein, PH-like domain superfamily, pleckstrin homology domain, protein family, RasGAP, SH3 domain, protein family, SH2 domain, protein family, Ras GTPase-activating protein 1, C-terminal SH2 domain, protein family, C2 domain, protein family, Ras GTPase-activating domain, protein family, Ras GTPase-activating protein 1, N-terminal SH2 domain, protein family, SH3 domain, protein family, Ras GTPase-activating protein, conserved site, protein family

Properties

Biological process negative regulation of neuron apoptotic process, negative regulation of cell adhesion, intracellular signal transduction, blood vessel morphogenesis, ephrin receptor signaling pathway, regulation of GTPase activity, mitotic cytokinesis, MAPK cascade, negative regulation of Ras protein signal transduction, negative regulation of cell-matrix adhesion, vasculogenesis, regulation of actin filament polymerization, positive regulation of GTPase activity, regulation of RNA metabolic process, regulation of cell shape, signal transduction, negative regulation of apoptotic process, negative regulation of Ras protein signal transduction

Cell component cytoplasm, cytosol, intrinsic component of the cytoplasmic side of the plasma membrane, ruffle, plasma membrane, cytoplasm

Encoded by RASA1

Exact match identifiers.org, purl.uniprot.org, www.ncbi.nlm.nih.gov

Found in taxon Homo sapiens

Has part(s) SH3 domain, pleckstrin homology domain, SH2 domain, Ras GTPase-activating protein, conserved site, Ras GTPase-activating domain, C2 domain, RasGAP, SH3 domain, Ras GTPase-activating protein 1, N-terminal SH2 domain, Ras GTPase-activating protein 1, C-terminal SH2 domain

Imported from wholeness_audit_2026-05-02

Molecular function potassium channel inhibitor activity, protein binding, GTPase binding, signaling receptor binding, GTPase activator activity, phosphotyrosine residue binding, GTPase activity, GTPase activator activity

External References (4)

Ensembl protein id ENSP00000274376, ENSP00000411221, ENSP00000422008, ENSP00000423395, ENSP00000420905

Pdb structure id 1WER, 1WQ1, 2GQI, 2J05, 2J06, 2M51, 4FSS, 2GSB

Refseq protein id NP_002881, NP_072179, XP_011541827, XP_011541829

Uniprot protein id P20936

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ RAS p21 protein activator 1 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ RAS p21 protein activator 1 — UniProt protein ID (P352): P20936. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ RAS p21 protein activator 1 — part of (P361): SH3-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ RAS p21 protein activator 1 — part of (P361): C2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ RAS p21 protein activator 1 — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ RAS p21 protein activator 1 — part of (P361): Ras GTPase-activating protein 1. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ RAS p21 protein activator 1 — part of (P361): Rho GTPase activation protein. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ RAS p21 protein activator 1 — part of (P361): PH-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ RAS p21 protein activator 1 — part of (P361): pleckstrin homology domain, protein family. wikidata.org.
[11] ↑ RAS p21 protein activator 1 — part of (P361): RasGAP, SH3 domain, protein family. wikidata.org.
[12] ↑ RAS p21 protein activator 1 — part of (P361): SH2 domain, protein family. wikidata.org.
[13] ↑ RAS p21 protein activator 1 — part of (P361): Ras GTPase-activating protein 1, C-terminal SH2 domain, protein family. wikidata.org.
[14] ↑ RAS p21 protein activator 1 — part of (P361): C2 domain, protein family. wikidata.org.
[15] ↑ RAS p21 protein activator 1 — part of (P361): Ras GTPase-activating domain, protein family. wikidata.org.
[16] ↑ RAS p21 protein activator 1 — part of (P361): Ras GTPase-activating protein 1, N-terminal SH2 domain, protein family. wikidata.org.
[17] ↑ RAS p21 protein activator 1 — part of (P361): SH3 domain, protein family. wikidata.org.
[18] ↑ RAS p21 protein activator 1 — part of (P361): Ras GTPase-activating protein, conserved site, protein family. wikidata.org.
[19] ↑ RAS p21 protein activator 1 — has part(s) (P527): SH3 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ RAS p21 protein activator 1 — has part(s) (P527): pleckstrin homology domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ RAS p21 protein activator 1 — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ RAS p21 protein activator 1 — has part(s) (P527): Ras GTPase-activating protein, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ RAS p21 protein activator 1 — has part(s) (P527): Ras GTPase-activating domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ RAS p21 protein activator 1 — has part(s) (P527): C2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ RAS p21 protein activator 1 — has part(s) (P527): RasGAP, SH3 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ RAS p21 protein activator 1 — has part(s) (P527): Ras GTPase-activating protein 1, N-terminal SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ RAS p21 protein activator 1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). RAS p21 protein activator 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/ras-p21-protein-activator-1

MLA

“RAS p21 protein activator 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ras-p21-protein-activator-1.

BibTeX

@misc{4ortxyz_ras-p21-protein-activator-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{RAS p21 protein activator 1}}, year = {2026}, url = {https://4ort.xyz/entity/ras-p21-protein-activator-1}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): RAS p21 protein activator 1 — https://4ort.xyz/entity/ras-p21-protein-activator-1 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/ras-p21-protein-activator-1 · Last refreshed: May 3, 2026