Raf-1 proto-oncogene, serine/threonine kinase

mammalian protein found in Homo sapiens
Protein protein Q410434
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Raf-1 proto-oncogene, serine/threonine kinase

Summary

Raf-1 proto-oncogene, serine/threonine kinase is a protein[1]. It draws 115 Wikipedia views per month (protein category, ranking #134 of 987).[2]

Key Facts

  • Raf-1 proto-oncogene, serine/threonine kinase's instance of is recorded as protein[3].
  • Raf-1 proto-oncogene, serine/threonine kinase's physically interacts with is recorded as sorafenib[4].
  • Raf-1 proto-oncogene, serine/threonine kinase's physically interacts with is recorded as vemurafenib[5].
  • Raf-1 proto-oncogene, serine/threonine kinase is part of Ubiquitin-like domain superfamily[6].
  • Raf-1 proto-oncogene, serine/threonine kinase is part of Protein kinase-like domain superfamily[7].
  • Raf-1 proto-oncogene, serine/threonine kinase is part of Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family[8].
  • Raf-1 proto-oncogene, serine/threonine kinase is part of Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family[9].
  • Raf-1 proto-oncogene, serine/threonine kinase is part of Diacylglycerol/phorbol-ester binding domain, protein family[10].
  • Raf-1 proto-oncogene, serine/threonine kinase is part of Raf-like Ras-binding domain, protein family[11].
  • Raf-1 proto-oncogene, serine/threonine kinase is part of Protein kinase domain, protein family[12].
  • Raf-1 proto-oncogene, serine/threonine kinase is part of Protein kinase, ATP binding site, protein family[13].
  • Raf-1 proto-oncogene, serine/threonine kinase is part of Serine/threonine-protein kinase, active site, protein family[14].
  • Raf-1 proto-oncogene, serine/threonine kinase comprises Raf-like Ras-binding[15].
  • Raf-1 proto-oncogene, serine/threonine kinase comprises protein kinase, ATP binding site[16].
  • Raf-1 proto-oncogene, serine/threonine kinase comprises protein kinase domain[17].
  • Raf-1 proto-oncogene, serine/threonine kinase comprises protein kinase C-like, phorbol ester/diacylglycerol-binding domain[18].
  • Raf-1 proto-oncogene, serine/threonine kinase comprises serine/threonine-protein kinase, active site[19].
  • Raf-1 proto-oncogene, serine/threonine kinase comprises serine-threonine/tyrosine-protein kinase, catalytic domain[20].
  • Raf-1 proto-oncogene, serine/threonine kinase comprises diacylglycerol/phorbol-ester binding[21].
  • Raf-1 proto-oncogene, serine/threonine kinase's molecular function is recorded as transferase activity[22].
  • Raf-1 proto-oncogene, serine/threonine kinase's molecular function is recorded as protein kinase activity[23].
  • Raf-1 proto-oncogene, serine/threonine kinase's molecular function is recorded as nucleotide binding[24].
  • Raf-1 proto-oncogene, serine/threonine kinase's molecular function is recorded as metal ion binding[25].
  • Raf-1 proto-oncogene, serine/threonine kinase's molecular function is recorded as protein serine/threonine kinase activity[26].
  • Raf-1 proto-oncogene, serine/threonine kinase's molecular function is recorded as small GTPase binding[27].

Why It Matters

Raf-1 proto-oncogene, serine/threonine kinase draws 115 Wikipedia views per month (protein category, ranking #134 of 987).[2] It has Wikipedia articles in 8 language editions, a strong signal of global cultural recognition.[28] It is known by 13 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [5] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . wikidata.org.
  9. [11] . wikidata.org.
  10. [12] . wikidata.org.
  11. [13] . wikidata.org.
  12. [14] . wikidata.org.
  13. [15] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . Bcl-2 targets the protein kinase Raf-1 to mitochondria. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . Di-Ras, a distinct subgroup of ras family GTPases with unique biochemical properties. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Raf-1 proto-oncogene, serine/threonine kinase. Retrieved May 3, 2026, from https://4ort.xyz/entity/raf-1-proto-oncogene-serine-threonine-kinase
MLA “Raf-1 proto-oncogene, serine/threonine kinase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/raf-1-proto-oncogene-serine-threonine-kinase.
BibTeX @misc{4ortxyz_raf-1-proto-oncogene-serine-threonine-kinase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Raf-1 proto-oncogene, serine/threonine kinase}}, year = {2026}, url = {https://4ort.xyz/entity/raf-1-proto-oncogene-serine-threonine-kinase}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Raf-1 proto-oncogene, serine/threonine kinase — https://4ort.xyz/entity/raf-1-proto-oncogene-serine-threonine-kinase (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/raf-1-proto-oncogene-serine-threonine-kinase · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 5w ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Instance of
    Part of
    Encoded by RAF1
    Biological process response to muscle stretch, regulation of apoptotic process, cell differentiation +38
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.7.11.1, [[:toollabs:quickstatements/#/batch/261446|batch #261446]]"
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