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R-spondin 1

mammalian protein found in Mus musculus
Protein protein Q21988509
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R-spondin 1

Summary

R-spondin 1 is a protein[1].

Key Facts

  • R-spondin 1's instance of is recorded as protein[2].
  • R-spondin 1's subclass of is recorded as protein[3].
  • R-spondin 1's UniProt protein ID is recorded as Q9Z132[4].
  • R-spondin 1's part of is recorded as Thrombospondin type-1 (TSP1) repeat superfamily[5].
  • R-spondin 1's part of is recorded as Growth factor receptor cysteine-rich domain superfamily[6].
  • R-spondin 1's part of is recorded as Thrombospondin type-1 (TSP1) repeat, protein family[7].
  • R-spondin 1's part of is recorded as Furin-like repeat, protein family[8].
  • R-spondin 1's has part is recorded as Furin-like repeat[9].
  • R-spondin 1's has part is recorded as Thrombospondin type-1 (TSP1) repeat[10].
  • R-spondin 1's RefSeq protein ID is recorded as NP_619624[11].
  • R-spondin 1's RefSeq protein ID is recorded as XP_006502925[12].
  • R-spondin 1's molecular function is recorded as heparin binding[13].
  • R-spondin 1's molecular function is recorded as signaling receptor binding[14].
  • R-spondin 1's molecular function is recorded as protein binding[15].
  • R-spondin 1's molecular function is recorded as G protein-coupled receptor binding[16].
  • R-spondin 1's molecular function is recorded as frizzled binding[17].
  • R-spondin 1's cell component is recorded as extracellular region[18].
  • R-spondin 1's cell component is recorded as nucleus[19].
  • R-spondin 1's cell component is recorded as extracellular space[20].
  • R-spondin 1's cell component is recorded as extracellular space[21].
  • R-spondin 1's biological process is recorded as positive regulation of canonical Wnt signaling pathway[22].
  • R-spondin 1's biological process is recorded as male meiotic nuclear division[23].
  • R-spondin 1's biological process is recorded as regulation of receptor internalization[24].
  • R-spondin 1's biological process is recorded as regulation of gene expression[25].
  • R-spondin 1's biological process is recorded as positive regulation of Wnt signaling pathway[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . Q905695. Retrieved . wikidata.org.
  2. [3] ↑ . Q905695. Retrieved . wikidata.org.
  3. [4] ↑ . Q905695. Retrieved . wikidata.org.
  4. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] ↑ . wikidata.org.
  7. [8] ↑ . wikidata.org.
  8. [9] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . Q20641742. Retrieved . wikidata.org.
  11. [12] ↑ . Q20641742. Retrieved . wikidata.org.
  12. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] ↑ . RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] ↑ . RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). R-spondin 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/r-spondin-1
MLA “R-spondin 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/r-spondin-1.
BibTeX @misc{4ortxyz_r-spondin-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{R-spondin 1}}, year = {2026}, url = {https://4ort.xyz/entity/r-spondin-1}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): R-spondin 1 — https://4ort.xyz/entity/r-spondin-1 (retrieved 2026-05-03)

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