Pyruvate kinase M1/2

mammalian protein found in Homo sapiens
Protein protein Q21116651
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Summary

Pyruvate kinase M1/2 is a protein[1]. It is known by 18 alternative names across languages and contexts.[2]

Key Facts

  • Molecular function: transferase activity[3], nucleotide binding[4], potassium ion binding[5], metal ion binding[6], kinase activity[7], catalytic activity[8], protein binding[9], MHC class II protein complex binding[10], ATP binding[11], magnesium ion binding[12], pyruvate kinase activity[13], RNA binding[14], cadherin binding[15], identical protein binding[16]
  • Cell component: cytoplasm[17], extracellular vesicle[18], vesicle[19], extracellular matrix[20], myelin sheath[21], cilium[22], mitochondrion[23], extracellular exosome[24], nucleus[25], extracellular region[26], cytosol[27], secretory granule lumen[28], ficolin-1-rich granule lumen[29], pyruvate kinase complex[30]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . JMJD8 Regulates Angiogenic Sprouting and Cellular Metabolism by Interacting With Pyruvate Kinase M2 in Endothelial Cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . Cytosolic thyroid hormone-binding protein is a monomer of pyruvate kinase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Pyruvate kinase M1/2. Retrieved May 3, 2026, from https://4ort.xyz/entity/pyruvate-kinase-m1-2-q21116651
MLA “Pyruvate kinase M1/2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/pyruvate-kinase-m1-2-q21116651.
BibTeX @misc{4ortxyz_pyruvate-kinase-m1-2-q21116651_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Pyruvate kinase M1/2}}, year = {2026}, url = {https://4ort.xyz/entity/pyruvate-kinase-m1-2-q21116651}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Pyruvate kinase M1/2 — https://4ort.xyz/entity/pyruvate-kinase-m1-2-q21116651 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 13w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → PKM
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → transferase activity, nucleotide binding, potassium ion binding +18
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 2.7.1.40, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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