Pyruvate dehydrogenase kinase 1

mammalian protein found in Homo sapiens
Protein protein Q7118823
Press Enter · cited answer in seconds

Summary

Pyruvate dehydrogenase kinase 1 is a protein[1]. It is known by 8 alternative names across languages and contexts.[2]

Key Facts

  • Pyruvate dehydrogenase kinase 1's instance of is recorded as protein[3].
  • Pyruvate dehydrogenase kinase 1's molecular function is recorded as transferase activity[4].
  • Pyruvate dehydrogenase kinase 1's molecular function is recorded as nucleotide binding[5].
  • Pyruvate dehydrogenase kinase 1's molecular function is recorded as protein kinase activity[6].
  • Pyruvate dehydrogenase kinase 1's molecular function is recorded as kinase activity[7].
  • Pyruvate dehydrogenase kinase 1's molecular function is recorded as protein binding[8].
  • Pyruvate dehydrogenase kinase 1's molecular function is recorded as ATP binding[9].
  • Pyruvate dehydrogenase kinase 1's molecular function is recorded as pyruvate dehydrogenase (acetyl-transferring) kinase activity[10].
  • Pyruvate dehydrogenase kinase 1's molecular function is recorded as protein kinase activity[11].
  • Pyruvate dehydrogenase kinase 1's molecular function is recorded as pyruvate dehydrogenase (acetyl-transferring) kinase activity[12].
  • Pyruvate dehydrogenase kinase 1's cell component is recorded as mitochondrial pyruvate dehydrogenase complex[13].
  • Pyruvate dehydrogenase kinase 1's cell component is recorded as mitochondrial matrix[14].
  • Pyruvate dehydrogenase kinase 1's cell component is recorded as nucleus[15].
  • Pyruvate dehydrogenase kinase 1's cell component is recorded as nucleolus[16].
  • Pyruvate dehydrogenase kinase 1's cell component is recorded as mitochondrion[17].
  • Pyruvate dehydrogenase kinase 1's biological process is recorded as intrinsic apoptotic signaling pathway in response to oxidative stress[18].
  • Pyruvate dehydrogenase kinase 1's biological process is recorded as phosphorylation[19].
  • Pyruvate dehydrogenase kinase 1's biological process is recorded as hypoxia-inducible factor-1alpha signaling pathway[20].
  • Pyruvate dehydrogenase kinase 1's biological process is recorded as regulation of acetyl-CoA biosynthetic process from pyruvate[21].
  • Pyruvate dehydrogenase kinase 1's biological process is recorded as regulation of glucose metabolic process[22].
  • Pyruvate dehydrogenase kinase 1's biological process is recorded as glucose metabolic process[23].
  • Pyruvate dehydrogenase kinase 1's biological process is recorded as cell population proliferation[24].
  • Pyruvate dehydrogenase kinase 1's biological process is recorded as protein phosphorylation[25].
  • Pyruvate dehydrogenase kinase 1's biological process is recorded as carbohydrate metabolic process[26].
  • Pyruvate dehydrogenase kinase 1's encoded by is recorded as PDK1[27].

Why It Matters

Pyruvate dehydrogenase kinase 1 is known by 8 alternative names across languages and contexts.[2]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . UniProt. Retrieved . wikidata.org.
  2. [4] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . Diversity of the pyruvate dehydrogenase kinase gene family in humans. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . Allosteric activation of the protein kinase PDK1 with low molecular weight compounds. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . Diversity of the pyruvate dehydrogenase kinase gene family in humans. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . Diversity of the pyruvate dehydrogenase kinase gene family in humans. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . Overexpression of pyruvate dehydrogenase kinase 3 increases drug resistance and early recurrence in colon cancer. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Diversity of the pyruvate dehydrogenase kinase gene family in humans. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Pyruvate dehydrogenase kinase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/pyruvate-dehydrogenase-kinase-1
MLA “Pyruvate dehydrogenase kinase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/pyruvate-dehydrogenase-kinase-1.
BibTeX @misc{4ortxyz_pyruvate-dehydrogenase-kinase-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Pyruvate dehydrogenase kinase 1}}, year = {2026}, url = {https://4ort.xyz/entity/pyruvate-dehydrogenase-kinase-1}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Pyruvate dehydrogenase kinase 1 — https://4ort.xyz/entity/pyruvate-dehydrogenase-kinase-1 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/pyruvate-dehydrogenase-kinase-1 · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Uniprot protein id → province of Aosta
    Ec enzyme number → 2.7.11.2
    Refseq protein id → NP_001265478, NP_002601, XP_006712657 +5
    Imported from → —
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 2.7.11.2, [[:toollabs:quickstatements/#/batch/261457|batch #261457]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.