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pyruvate dehydrogenase complex

Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenas
Class type of: oxidoreductase complex, oxidoreductase Q412856

Facts

5 properties
Instance of
cellular component, group or class of enzymes, family of protein complexes[2][3]
Subclass of
oxidoreductase complex, oxidoreductase[4][5]
Part of
cytoplasm[6]
Has part(s) of the class
Dihydrolipoamide dehydrogenase, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Pyruvate dehydrogenase E1 component subunit beta, Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y[8][9][10][11]
Molecular function
pyruvate dehydrogenase (NAD+) activity[7]
🏷️ Also known as
en GO:0045254 en pyruvate dehydrogenase complex en pyruvate dehydrogenase complex (lipoamide) ar معقد نازعة هيدروجين البيروفات ar مركب نازعة هيدروجين بيروفات cs pyruvátdehydrogenáza cs PDC cs pyruvátdehydrogenasa cs pyruvát dehydrogenáza de Pyruvat-Dehydrogenase-Komplex de Pyruvat-Dehydrogenase de Pyruvatdehydrogenase-Komplex fi Pyruvaattidehydrogenaasikompleksi fr complexe pyruvate déshydrogénase he פירובט דהידרוגנאז id Kompleks piruvat dehidrogenase it Complesso enzimatico piruvato deidrogenasi it Complesso della piruvato deidrogenasi it Complesso enzimatico della piruvato deidrogenasi it Complesso multienzimatico della piruvato deidrogenasi
🔖 Identifiers · 10
OpenAlex ID
C88099638
Encyclopædia Britannica Online ID
science/pyruvate-dehydrogenase-complex
Exact match
purl.obolibrary.org
Freebase ID
/m/02jw63
Gene Ontology ID
GO:0045254
MeSH descriptor ID
D011768
MeSH tree code
D05.500.562.625, D08.811.600.741
Microsoft Academic ID (discontinued)
88099638
UMLS CUI
C0034344, C1167289
WikiSkripta article ID
12845

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🔗 Connections
← Cell component 3
pyruvate dehydrogenase (acetyl-transferring), Dihydrolipoamide S-acetyltransferase, Dihydrolipoamide dehydrogenase
Part of 1
cytoplasm
Subclass of 1
oxidoreductase
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Summary

pyruvate dehydrogenase complex is a cellular component[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . wikidata.org.
  2. [3] ↑ . wikidata.org.
  3. [4] ↑ . Gene Ontology release 2019-10-07. Retrieved . wikidata.org.
  4. [5] ↑ . Retrieved . Provenance: wikidata.org.
  5. [6] ↑ . Gene Ontology release 2019-10-07. Retrieved . wikidata.org.
  6. [7] ↑ . Gene Ontology release 2019-11-16. wikidata.org.
  7. [8] ↑ . Gene Ontology. wikidata.org.
  8. [9] ↑ . Gene Ontology. wikidata.org.
  9. [10] ↑ . InterPro. wikidata.org.
  10. [11] ↑ . InterPro. wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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APA 4ort.xyz Knowledge Graph. (2026). pyruvate dehydrogenase complex. Retrieved November 6, 2026, from https://4ort.xyz/entity/pyruvate-dehydrogenase-complex
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BibTeX @misc{4ortxyz_pyruvate-dehydrogenase-complex_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{pyruvate dehydrogenase complex}}, year = {2026}, url = {https://4ort.xyz/entity/pyruvate-dehydrogenase-complex}, note = {Accessed: 2026-11-06}}
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