Purine rich element binding protein A

mammalian protein found in Homo sapiens

Protein protein Q21122341

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Summary

Purine rich element binding protein An is a protein^[1].

Key Facts

Purine rich element binding protein A's instance of is recorded as protein^[2].
Purine rich element binding protein A's UniProt protein ID is recorded as Q00577^[3].
Purine rich element binding protein A's part of is recorded as Purine-rich element-binding protein alpha^[4].
Purine rich element binding protein A's RefSeq protein ID is recorded as NP_005850^[5].
Purine rich element binding protein A's molecular function is recorded as DNA binding^[6].
Purine rich element binding protein A's molecular function is recorded as double-stranded telomeric DNA binding^[7].
Purine rich element binding protein A's molecular function is recorded as DNA-binding transcription factor activity^[8].
Purine rich element binding protein A's molecular function is recorded as transcription factor binding^[9].
Purine rich element binding protein A's molecular function is recorded as purine-rich negative regulatory element binding^[10].
Purine rich element binding protein A's molecular function is recorded as translation repressor activity, mRNA regulatory element binding^[11].
Purine rich element binding protein A's molecular function is recorded as single-stranded DNA binding^[12].
Purine rich element binding protein A's molecular function is recorded as protein binding^[13].
Purine rich element binding protein A's molecular function is recorded as transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding^[14].
Purine rich element binding protein A's molecular function is recorded as double-stranded DNA binding^[15].
Purine rich element binding protein A's molecular function is recorded as SMAD binding^[16].
Purine rich element binding protein A's molecular function is recorded as RNA binding^[17].
Purine rich element binding protein A's molecular function is recorded as RNA polymerase II transcription regulatory region sequence-specific DNA binding^[18].
Purine rich element binding protein A's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific^[19].
Purine rich element binding protein A's molecular function is recorded as DNA-binding transcription repressor activity, RNA polymerase II-specific^[20].
Purine rich element binding protein A's molecular function is recorded as double-stranded DNA binding^[21].
Purine rich element binding protein A's molecular function is recorded as RNA binding^[22].
Purine rich element binding protein A's molecular function is recorded as purine-rich negative regulatory element binding^[23].
Purine rich element binding protein A's molecular function is recorded as sequence-specific DNA binding^[24].
Purine rich element binding protein A's molecular function is recorded as RNA polymerase II transcription regulatory region sequence-specific DNA binding^[25].
Purine rich element binding protein A's cell component is recorded as cytoplasm^[26].

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Quick Facts

Instance of protein

Part of Purine-rich element-binding protein alpha

Properties

Biological process cell differentiation, negative regulation of translation, regulation of transcription, DNA-templated, transcription, DNA-templated, nervous system development, regulation of cell population proliferation, DNA replication initiation, positive regulation of cell population proliferation, negative regulation of transcription, DNA-templated, DNA unwinding involved in DNA replication, regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase II, dendritic transport of messenger ribonucleoprotein complex, lymphocyte proliferation, epithelial cell proliferation

Cell component cytoplasm, soma, dendrite, DNA replication factor A complex, nucleus, nucleus, dendrite cytoplasm, postsynapse, glutamatergic synapse

Encoded by PURA

Found in taxon Homo sapiens

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, double-stranded telomeric DNA binding, DNA-binding transcription factor activity, transcription factor binding, purine-rich negative regulatory element binding, translation repressor activity, mRNA regulatory element binding, single-stranded DNA binding, protein binding, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding, double-stranded DNA binding, SMAD binding, RNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, double-stranded DNA binding, RNA binding, purine-rich negative regulatory element binding, sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding

External References (3)

Ensembl protein id ENSP00000332706

Refseq protein id NP_005850

Uniprot protein id Q00577

🏷️ Also known as

en PURA en Purine rich element binding protein A en purine-rich single-stranded DNA-binding protein alpha en transcriptional activator protein Pur-alpha

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Purine rich element binding protein A — instance of (P31): protein. UniProt. Retrieved 2019-01-16. wikidata.org.
[3] ↑ Purine rich element binding protein A — UniProt protein ID (P352): Q00577. UniProt. Retrieved 2019-01-16. wikidata.org.
[4] ↑ Purine rich element binding protein A — part of (P361): Purine-rich element-binding protein alpha. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Purine rich element binding protein A — RefSeq protein ID (P637): NP_005850. Q20641742. Retrieved 2018-11-16. wikidata.org.
[6] ↑ Purine rich element binding protein A — molecular function (P680): DNA binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Purine rich element binding protein A — molecular function (P680): double-stranded telomeric DNA binding. Mechanism of DNA binding and localized strand separation by Pur alpha and comparison with Pur family member, Pur beta. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Purine rich element binding protein A — molecular function (P680): DNA-binding transcription factor activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Purine rich element binding protein A — molecular function (P680): transcription factor binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Purine rich element binding protein A — molecular function (P680): purine-rich negative regulatory element binding. GOA. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Purine rich element binding protein A — molecular function (P680): translation repressor activity, mRNA regulatory element binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Purine rich element binding protein A — molecular function (P680): single-stranded DNA binding. Sequence of cDNA comprising the human pur gene and sequence-specific single-stranded-DNA-binding properties of the encoded protein. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Purine rich element binding protein A — molecular function (P680): protein binding. Association of Human Purα with the Retinoblastoma Protein, Rb, Regulates Binding to the Single-stranded DNA Purα Recognition Element. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Purine rich element binding protein A — molecular function (P680): transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. Sequence of cDNAs Encoding Components of Vascular Actin Single-stranded DNA-binding Factor 2 Establish Identity to Purα and Purβ. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Purine rich element binding protein A — molecular function (P680): double-stranded DNA binding. GOA. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Purine rich element binding protein A — molecular function (P680): SMAD binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Purine rich element binding protein A — molecular function (P680): RNA binding. GOA. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Purine rich element binding protein A — molecular function (P680): RNA polymerase II transcription regulatory region sequence-specific DNA binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Purine rich element binding protein A — molecular function (P680): DNA-binding transcription factor activity, RNA polymerase II-specific. Sequence of cDNAs Encoding Components of Vascular Actin Single-stranded DNA-binding Factor 2 Establish Identity to Purα and Purβ. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Purine rich element binding protein A — molecular function (P680): DNA-binding transcription repressor activity, RNA polymerase II-specific. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Purine rich element binding protein A — molecular function (P680): double-stranded DNA binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Purine rich element binding protein A — molecular function (P680): RNA binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Purine rich element binding protein A — molecular function (P680): purine-rich negative regulatory element binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Purine rich element binding protein A — molecular function (P680): sequence-specific DNA binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Purine rich element binding protein A — molecular function (P680): RNA polymerase II transcription regulatory region sequence-specific DNA binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Purine rich element binding protein A — cell component (P681): cytoplasm. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Purine rich element binding protein A is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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MLA

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BibTeX

@misc{4ortxyz_purine-rich-element-binding-protein-a_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Purine rich element binding protein A}}, year = {2026}, url = {https://4ort.xyz/entity/purine-rich-element-binding-protein-a}, note = {Accessed: 2026-05-03}}

LLM prompt

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