Protein tyrosine phosphatase receptor type U

mammalian protein found in Homo sapiens
Protein protein Q21119234
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Summary

Protein tyrosine phosphatase receptor type U is a protein[1]. It is known by 16 alternative names across languages and contexts.[2]

Key Facts

  • Part of: Fibronectin type III superfamily[3], Immunoglobulin-like fold[4], Immunoglobulin-like domain superfamily[5], Concanavalin A-like lectin/glucanase domain superfamily[6], Protein-tyrosine phosphatase-like[7], Fibronectin type III, protein family[8], Tyrosine specific protein phosphatases domain, protein family[9], MAM domain, protein family[10], PTP type protein phosphatase domain, protein family[11], Protein-tyrosine phosphatase, catalytic domain, protein family[12], Protein-tyrosine phosphatase, active site, protein family[13]
  • Has part(s): fibronectin type III[14], MAM domain[15], Tyrosine specific protein phosphatases domain[16], Protein-tyrosine phosphatase, active site[17], PTP type protein phosphatase domain[18], Protein-tyrosine phosphatase, catalytic[19]
  • Molecular function: beta-catenin binding[20], phosphoprotein phosphatase activity[21], phosphatase activity[22], protein binding[23], transmembrane receptor protein tyrosine phosphatase activity[24], hydrolase activity[25], protein tyrosine phosphatase activity[26], identical protein binding[27]
  • Cell component: integral component of membrane[28], membrane[29], cell-cell junction[30], integral component of plasma membrane[31], cell junction[32], plasma membrane[33]
  • Biological process: cell differentiation[34], response to glucocorticoid[35], homotypic cell-cell adhesion[36], transmembrane receptor protein tyrosine phosphatase signaling pathway[37], negative regulation of cell migration[38], protein localization to cell surface[39], animal organ regeneration[40], canonical Wnt signaling pathway[41], negative regulation of cell population proliferation[42], dephosphorylation[43], cell adhesion[44], peptidyl-tyrosine dephosphorylation[45], protein dephosphorylation[46], cell-cell adhesion[47]
  • Encoded by: PTPRU[48]
  • Found in taxon: Homo sapiens[49]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . wikidata.org.
  10. [12] ↑ . wikidata.org.
  11. [13] ↑ . wikidata.org.
  12. [14] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Involvement of beta3A subunit of adaptor protein-3 in intracellular trafficking of receptor-like protein tyrosine phosphatase PCP-2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . Characterization of PCP-2, a novel receptor protein tyrosine phosphatase of the MAM domain family. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . Transmembrane homodimerization of receptor-like protein tyrosine phosphatases. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . Physical and functional interaction between receptor-like protein tyrosine phosphatase PCP-2 and beta-catenin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . Characterization of PCP-2, a novel receptor protein tyrosine phosphatase of the MAM domain family. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [37] ↑ . Characterization of PCP-2, a novel receptor protein tyrosine phosphatase of the MAM domain family. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  36. [38] ↑ . Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  37. [39] ↑ . Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  38. [40] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  39. [41] ↑ . Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  40. [42] ↑ . Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  41. [43] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  42. [44] ↑ . Characterization of PCP-2, a novel receptor protein tyrosine phosphatase of the MAM domain family. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  43. [45] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  44. [46] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  45. [47] ↑ . Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  46. [48] ↑ . UniProt. Retrieved . wikidata.org.
  47. [49] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

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APA 4ort.xyz Knowledge Graph. (2026). Protein tyrosine phosphatase receptor type U. Retrieved May 3, 2026, from https://4ort.xyz/entity/protein-tyrosine-phosphatase-receptor-type-u
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BibTeX @misc{4ortxyz_protein-tyrosine-phosphatase-receptor-type-u_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Protein tyrosine phosphatase receptor type U}}, year = {2026}, url = {https://4ort.xyz/entity/protein-tyrosine-phosphatase-receptor-type-u}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → PTPRU
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → beta-catenin binding, phosphoprotein phosphatase activity, phosphatase activity +6
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 3.1.3.48, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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