Protein tyrosine phosphatase non-receptor type 2

mammalian protein found in Homo sapiens

Protein protein Q21171735

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Protein tyrosine phosphatase non-receptor type 2

Summary

Protein tyrosine phosphatase non-receptor type 2 is a protein^[1].

Key Facts

Protein tyrosine phosphatase non-receptor type 2's instance of is recorded as protein^[2].
Protein tyrosine phosphatase non-receptor type 2's UniProt protein ID is recorded as P17706^[3].
Protein tyrosine phosphatase non-receptor type 2's part of is recorded as Protein-tyrosine phosphatase, non-receptor type-1/2^[4].
Protein tyrosine phosphatase non-receptor type 2's part of is recorded as Protein-tyrosine phosphatase-like^[5].
Protein tyrosine phosphatase non-receptor type 2's part of is recorded as membrane protein^[6].
Protein tyrosine phosphatase non-receptor type 2's part of is recorded as Tyrosine specific protein phosphatases domain, protein family^[7].
Protein tyrosine phosphatase non-receptor type 2's part of is recorded as PTP type protein phosphatase domain, protein family^[8].
Protein tyrosine phosphatase non-receptor type 2's part of is recorded as Protein-tyrosine phosphatase, catalytic domain, protein family^[9].
Protein tyrosine phosphatase non-receptor type 2's part of is recorded as Protein-tyrosine phosphatase, active site, protein family^[10].
Protein tyrosine phosphatase non-receptor type 2's MeSH descriptor ID is recorded as D054578^[11].
Protein tyrosine phosphatase non-receptor type 2's has part is recorded as Protein-tyrosine phosphatase, active site^[12].
Protein tyrosine phosphatase non-receptor type 2's has part is recorded as Tyrosine specific protein phosphatases domain^[13].
Protein tyrosine phosphatase non-receptor type 2's has part is recorded as PTP type protein phosphatase domain^[14].
Protein tyrosine phosphatase non-receptor type 2's has part is recorded as Protein-tyrosine phosphatase, catalytic^[15].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as NP_001193942^[16].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as NP_001295216^[17].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as NP_002819^[18].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as NP_536347^[19].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as NP_536348^[20].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as XP_005258181^[21].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as XP_005258182^[22].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as XP_011524007^[23].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as XP_011524008^[24].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as XP_011524009^[25].
Protein tyrosine phosphatase non-receptor type 2's RefSeq protein ID is recorded as XP_016881373^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of Protein-tyrosine phosphatase, non-receptor type-1/2, Protein-tyrosine phosphatase-like, membrane protein, Tyrosine specific protein phosphatases domain, protein family, PTP type protein phosphatase domain, protein family, Protein-tyrosine phosphatase, catalytic domain, protein family, Protein-tyrosine phosphatase, active site, protein family

Properties

Biological process negative regulation of type I interferon-mediated signaling pathway, negative regulation of epidermal growth factor receptor signaling pathway, positive regulation of PERK-mediated unfolded protein response, dephosphorylation, negative regulation of interleukin-4-mediated signaling pathway, positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, negative regulation of interleukin-6-mediated signaling pathway, negative regulation of cell population proliferation, protein dephosphorylation, negative regulation of interleukin-2-mediated signaling pathway, regulation of interferon-gamma-mediated signaling pathway, negative regulation of protein tyrosine kinase activity, regulation of hepatocyte growth factor receptor signaling pathway, negative regulation of platelet-derived growth factor receptor-beta signaling pathway, insulin receptor signaling pathway, negative regulation of interferon-gamma-mediated signaling pathway, glucose homeostasis, negative regulation of chemotaxis, negative regulation of tumor necrosis factor-mediated signaling pathway, negative regulation of macrophage differentiation, negative regulation of T cell receptor signaling pathway, negative regulation of positive thymic T cell selection, negative regulation of insulin receptor signaling pathway, T cell differentiation, negative regulation of ERK1 and ERK2 cascade, erythrocyte differentiation, negative regulation of lipid storage, B cell differentiation, peptidyl-tyrosine dephosphorylation, positive regulation of gluconeogenesis, negative regulation of macrophage colony-stimulating factor signaling pathway, negative regulation of inflammatory response, negative regulation of transcription by RNA polymerase II, negative regulation of tyrosine phosphorylation of STAT protein, cellular response to cytokine stimulus, peptidyl-tyrosine dephosphorylation, negative regulation of tyrosine phosphorylation of STAT protein, negative regulation of interleukin-6-mediated signaling pathway, negative regulation of interleukin-4-mediated signaling pathway

Cell component cytoplasm, membrane, plasma membrane, endoplasmic reticulum, nucleus, endoplasmic reticulum-Golgi intermediate compartment, nucleoplasm, cytosol, nucleus

Encoded by PTPN2

Found in taxon Homo sapiens

Has part(s) Protein-tyrosine phosphatase, active site, Tyrosine specific protein phosphatases domain, PTP type protein phosphatase domain, Protein-tyrosine phosphatase, catalytic

Imported from wholeness_audit_2026-05-02

Molecular function protein binding, protein kinase binding, phosphatase activity, integrin binding, phosphoprotein phosphatase activity, syntaxin binding, non-membrane spanning protein tyrosine phosphatase activity, receptor tyrosine kinase binding, hydrolase activity, protein tyrosine phosphatase activity, STAT family protein binding, protein tyrosine phosphatase activity

External References (6)

Ensembl protein id ENSP00000311857, ENSP00000320298, ENSP00000320546, ENSP00000466936, ENSP00000464719, ENSP00000464937, ENSP00000466206, ENSP00000467043, ENSP00000467823, ENSP00000468012, ENSP00000468155, ENSP00000468408, ENSP00000496181, ENSP00000494336, ENSP00000493693

Mesh descriptor id D054578

Mesh tree code D08.811.277.352.650.775.300.200, D12.776.476.564.300.200

Pdb structure id 1L8K

Refseq protein id NP_001193942, NP_001295216, NP_002819, NP_536347, NP_536348, XP_005258181, XP_005258182, XP_011524007, XP_011524008, XP_011524009, XP_016881373, XP_016881374, XP_016881375, XP_016881376, XP_016881377, XP_024306996, XP_024306997, XP_024306998

Uniprot protein id P17706

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Protein tyrosine phosphatase non-receptor type 2 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Protein tyrosine phosphatase non-receptor type 2 — UniProt protein ID (P352): P17706. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Protein tyrosine phosphatase non-receptor type 2 — part of (P361): Protein-tyrosine phosphatase, non-receptor type-1/2. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Protein tyrosine phosphatase non-receptor type 2 — part of (P361): Protein-tyrosine phosphatase-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Protein tyrosine phosphatase non-receptor type 2 — part of (P361): membrane protein. wikidata.org.
[7] ↑ Protein tyrosine phosphatase non-receptor type 2 — part of (P361): Tyrosine specific protein phosphatases domain, protein family. wikidata.org.
[8] ↑ Protein tyrosine phosphatase non-receptor type 2 — part of (P361): PTP type protein phosphatase domain, protein family. wikidata.org.
[9] ↑ Protein tyrosine phosphatase non-receptor type 2 — part of (P361): Protein-tyrosine phosphatase, catalytic domain, protein family. wikidata.org.
[10] ↑ Protein tyrosine phosphatase non-receptor type 2 — part of (P361): Protein-tyrosine phosphatase, active site, protein family. wikidata.org.
[11] ↑ Protein tyrosine phosphatase non-receptor type 2 — MeSH descriptor ID (P486): D054578. wikidata.org.
[12] ↑ Protein tyrosine phosphatase non-receptor type 2 — has part(s) (P527): Protein-tyrosine phosphatase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Protein tyrosine phosphatase non-receptor type 2 — has part(s) (P527): Tyrosine specific protein phosphatases domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Protein tyrosine phosphatase non-receptor type 2 — has part(s) (P527): PTP type protein phosphatase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Protein tyrosine phosphatase non-receptor type 2 — has part(s) (P527): Protein-tyrosine phosphatase, catalytic. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): NP_001193942. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): NP_001295216. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): NP_002819. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): NP_536347. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): NP_536348. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): XP_005258181. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): XP_005258182. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): XP_011524007. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): XP_011524008. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): XP_011524009. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ Protein tyrosine phosphatase non-receptor type 2 — RefSeq protein ID (P637): XP_016881373. Q20641742. Retrieved 2020-05-30. wikidata.org.

Class ancestry

[1] ↑ Protein tyrosine phosphatase non-receptor type 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

“Protein tyrosine phosphatase non-receptor type 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/protein-tyrosine-phosphatase-non-receptor-type-2.

BibTeX

@misc{4ortxyz_protein-tyrosine-phosphatase-non-receptor-type-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Protein tyrosine phosphatase non-receptor type 2}}, year = {2026}, url = {https://4ort.xyz/entity/protein-tyrosine-phosphatase-non-receptor-type-2}, note = {Accessed: 2026-05-03}}

LLM prompt

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