Protein kinase N1

mammalian protein found in Homo sapiens

Protein protein Q21112525

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Protein kinase N1

Summary

Protein kinase N1 is a protein^[1].

Key Facts

Protein kinase N1's instance of is recorded as protein^[2].
Protein kinase N1's physically interacts with is recorded as staurosporine^[3].
Protein kinase N1's UniProt protein ID is recorded as Manzanares^[4].
Protein kinase N1's part of is recorded as HR1 repeat superfamily^[5].
Protein kinase N1's part of is recorded as Protein kinase-like domain superfamily^[6].
Protein kinase N1's part of is recorded as Protein kinase, C-terminal domain, protein family^[7].
Protein kinase N1's part of is recorded as Serine/threonine-protein kinase N, C2 domain, protein family^[8].
Protein kinase N1's part of is recorded as AGC-kinase, C-terminal domain, protein family^[9].
Protein kinase N1's part of is recorded as Serine/threonine-protein kinase N1, second HR1 domain, protein family^[10].
Protein kinase N1's part of is recorded as HR1 rho-binding domain, protein family^[11].
Protein kinase N1's part of is recorded as Protein kinase domain, protein family^[12].
Protein kinase N1's part of is recorded as Protein kinase, ATP binding site, protein family^[13].
Protein kinase N1's part of is recorded as Serine/threonine-protein kinase N, first HR1 domain, protein family^[14].
Protein kinase N1's part of is recorded as Serine/threonine-protein kinase, active site, protein family^[15].
Protein kinase N1's has part is recorded as AGC-kinase, C-terminal^[16].
Protein kinase N1's has part is recorded as protein kinase, ATP binding site^[17].
Protein kinase N1's has part is recorded as protein kinase domain^[18].
Protein kinase N1's has part is recorded as protein kinase, C-terminal^[19].
Protein kinase N1's has part is recorded as serine/threonine-protein kinase, active site^[20].
Protein kinase N1's has part is recorded as HR1 rho-binding domain^[21].
Protein kinase N1's has part is recorded as Serine/threonine-protein kinase N, first HR1 domain^[22].
Protein kinase N1's has part is recorded as Serine/threonine-protein kinase N1, second HR1 domain^[23].
Protein kinase N1's has part is recorded as Serine/threonine-protein kinase N, C2 domain^[24].
Protein kinase N1's RefSeq protein ID is recorded as NP_002732^[25].
Protein kinase N1's RefSeq protein ID is recorded as NP_998725^[26].

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Quick Facts

Instance of protein

Part of HR1 repeat superfamily, Protein kinase-like domain superfamily, Protein kinase, C-terminal domain, protein family, Serine/threonine-protein kinase N, C2 domain, protein family, AGC-kinase, C-terminal domain, protein family, Serine/threonine-protein kinase N1, second HR1 domain, protein family, HR1 rho-binding domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Serine/threonine-protein kinase N, first HR1 domain, protein family, Serine/threonine-protein kinase, active site, protein family

Properties

Biological process regulation of germinal center formation, negative regulation of protein phosphorylation, renal system process, regulation of transcription, DNA-templated, B cell apoptotic process, negative regulation of protein kinase activity, phosphorylation, regulation of transcription by RNA polymerase II, B cell homeostasis, spleen development, hyperosmotic response, transcription, DNA-templated, regulation of cell motility, protein phosphorylation, peptidyl-serine phosphorylation, epithelial cell migration, negative regulation of B cell proliferation, regulation of immunoglobulin production, signal transduction, chromatin organization, positive regulation of nucleic acid-templated transcription, intracellular signal transduction

Cell component cytoplasm, cytosol, endosome, membrane, plasma membrane, nucleoplasm, midbody, cleavage furrow, nucleus, cytoplasmic vesicle, protein-containing complex

Encoded by PKN1

Found in taxon Homo sapiens

Has part(s) AGC-kinase, C-terminal, protein kinase, ATP binding site, protein kinase domain, protein kinase, C-terminal, serine/threonine-protein kinase, active site, HR1 rho-binding domain, Serine/threonine-protein kinase N, first HR1 domain, Serine/threonine-protein kinase N1, second HR1 domain, Serine/threonine-protein kinase N, C2 domain

Imported from wholeness_audit_2026-05-02

Molecular function transferase activity, protein kinase activity, nucleotide binding, protein kinase C activity, histone binding, histone deacetylase binding, chromatin binding, histone kinase activity (H3-T11 specific), kinase activity, protein serine/threonine kinase activity, protein binding, androgen receptor binding, nuclear receptor coactivator activity, ATP binding, protein kinase C binding, protein serine/threonine kinase activity

Physically interacts with staurosporine

External References (4)

Ensembl protein id ENSP00000242783, ENSP00000343325, ENSP00000465842, ENSP00000465867, ENSP00000466367, ENSP00000466819, ENSP00000467422, ENSP00000468497

Pdb structure id 1CXZ, 1URF, 2RMK, 4NKG, 4OTD, 4OTG, 4OTH, 4OTI

Refseq protein id NP_002732, NP_998725

Uniprot protein id Manzanares

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Protein kinase N1 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Protein kinase N1 — physically interacts with (P129): staurosporine. IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved 2016-08-17. wikidata.org.
[4] ↑ Protein kinase N1 — UniProt protein ID (P352): Manzanares. Q905695. Retrieved 2019-11-13. wikidata.org.
[5] ↑ Protein kinase N1 — part of (P361): HR1 repeat superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Protein kinase N1 — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Protein kinase N1 — part of (P361): Protein kinase, C-terminal domain, protein family. wikidata.org.
[8] ↑ Protein kinase N1 — part of (P361): Serine/threonine-protein kinase N, C2 domain, protein family. wikidata.org.
[9] ↑ Protein kinase N1 — part of (P361): AGC-kinase, C-terminal domain, protein family. wikidata.org.
[10] ↑ Protein kinase N1 — part of (P361): Serine/threonine-protein kinase N1, second HR1 domain, protein family. wikidata.org.
[11] ↑ Protein kinase N1 — part of (P361): HR1 rho-binding domain, protein family. wikidata.org.
[12] ↑ Protein kinase N1 — part of (P361): Protein kinase domain, protein family. wikidata.org.
[13] ↑ Protein kinase N1 — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[14] ↑ Protein kinase N1 — part of (P361): Serine/threonine-protein kinase N, first HR1 domain, protein family. wikidata.org.
[15] ↑ Protein kinase N1 — part of (P361): Serine/threonine-protein kinase, active site, protein family. wikidata.org.
[16] ↑ Protein kinase N1 — has part(s) (P527): AGC-kinase, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Protein kinase N1 — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Protein kinase N1 — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Protein kinase N1 — has part(s) (P527): protein kinase, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Protein kinase N1 — has part(s) (P527): serine/threonine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Protein kinase N1 — has part(s) (P527): HR1 rho-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Protein kinase N1 — has part(s) (P527): Serine/threonine-protein kinase N, first HR1 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Protein kinase N1 — has part(s) (P527): Serine/threonine-protein kinase N1, second HR1 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Protein kinase N1 — has part(s) (P527): Serine/threonine-protein kinase N, C2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Protein kinase N1 — RefSeq protein ID (P637): NP_002732. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ Protein kinase N1 — RefSeq protein ID (P637): NP_998725. Q20641742. Retrieved 2020-05-30. wikidata.org.

Class ancestry

[1] ↑ Protein kinase N1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Protein kinase N1. Retrieved May 3, 2026, from https://4ort.xyz/entity/protein-kinase-n1

MLA “Protein kinase N1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/protein-kinase-n1.

BibTeX

@misc{4ortxyz_protein-kinase-n1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Protein kinase N1}}, year = {2026}, url = {https://4ort.xyz/entity/protein-kinase-n1}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Protein kinase N1 — https://4ort.xyz/entity/protein-kinase-n1 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/protein-kinase-n1 · Last refreshed: May 3, 2026