Protein kinase, DNA activated, catalytic polypeptide

mammalian protein found in Mus musculus

Protein protein Q21498359

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Summary

Protein kinase, DNA activated, catalytic polypeptide is a protein^[1].

Key Facts

Protein kinase, DNA activated, catalytic polypeptide's instance of is recorded as protein^[2].
Protein kinase, DNA activated, catalytic polypeptide's subclass of is recorded as protein^[3].
Protein kinase, DNA activated, catalytic polypeptide's UniProt protein ID is recorded as P97313^[4].
Protein kinase, DNA activated, catalytic polypeptide's part of is recorded as Protein kinase-like domain superfamily^[5].
Protein kinase, DNA activated, catalytic polypeptide's part of is recorded as Armadillo-type fold^[6].
Protein kinase, DNA activated, catalytic polypeptide's part of is recorded as Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily^[7].
Protein kinase, DNA activated, catalytic polypeptide's part of is recorded as Phosphatidylinositol 3-/4-kinase, catalytic domain, protein family^[8].
Protein kinase, DNA activated, catalytic polypeptide's part of is recorded as DNA-dependent protein kinase catalytic subunit, catalytic domain, protein family^[9].
Protein kinase, DNA activated, catalytic polypeptide's part of is recorded as PIK-related kinase, FAT family^[10].
Protein kinase, DNA activated, catalytic polypeptide's part of is recorded as NUC194 domain, protein family^[11].
Protein kinase, DNA activated, catalytic polypeptide's part of is recorded as PIK-related kinase family^[12].
Protein kinase, DNA activated, catalytic polypeptide's part of is recorded as FATC domain, protein family^[13].
Protein kinase, DNA activated, catalytic polypeptide's part of is recorded as Phosphatidylinositol 3/4-kinase, conserved site, protein family^[14].
Protein kinase, DNA activated, catalytic polypeptide's has part is recorded as PIK-related kinase, FAT^[15].
Protein kinase, DNA activated, catalytic polypeptide's has part is recorded as FATC domain^[16].
Protein kinase, DNA activated, catalytic polypeptide's has part is recorded as PIK-related kinase^[17].
Protein kinase, DNA activated, catalytic polypeptide's has part is recorded as Phosphatidylinositol 3-/4-kinase, catalytic domain^[18].
Protein kinase, DNA activated, catalytic polypeptide's has part is recorded as Phosphatidylinositol 3/4-kinase, conserved site^[19].
Protein kinase, DNA activated, catalytic polypeptide's has part is recorded as NUC194^[20].
Protein kinase, DNA activated, catalytic polypeptide's has part is recorded as DNA-dependent protein kinase catalytic subunit, catalytic domain^[21].
Protein kinase, DNA activated, catalytic polypeptide's RefSeq protein ID is recorded as NP_035289^[22].
Protein kinase, DNA activated, catalytic polypeptide's RefSeq protein ID is recorded as XP_006521924^[23].
Protein kinase, DNA activated, catalytic polypeptide's RefSeq protein ID is recorded as XP_017172381^[24].
Protein kinase, DNA activated, catalytic polypeptide's molecular function is recorded as enzyme binding^[25].
Protein kinase, DNA activated, catalytic polypeptide's molecular function is recorded as protein serine/threonine kinase activity^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Protein kinase-like domain superfamily, Armadillo-type fold, Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily, Phosphatidylinositol 3-/4-kinase, catalytic domain, protein family, DNA-dependent protein kinase catalytic subunit, catalytic domain, protein family, PIK-related kinase, FAT family, NUC194 domain, protein family, PIK-related kinase family, FATC domain, protein family, Phosphatidylinositol 3/4-kinase, conserved site, protein family

Properties

Biological process cellular response to insulin stimulus, positive regulation of apoptotic process, immunoglobulin V(D)J recombination, lymphocyte differentiation, somitogenesis, rhythmic process, regulation of smooth muscle cell proliferation, V(D)J recombination, regulation of circadian rhythm, T cell lineage commitment, response to ionizing radiation, peptidyl-serine phosphorylation, response to gamma radiation, negative regulation of protein phosphorylation, intrinsic apoptotic signaling pathway in response to DNA damage, development of the heart, positive regulation of transcription by RNA polymerase II, telomere capping, protein destabilization, double-strand break repair, cellular response to DNA damage stimulus, double-strand break repair via nonhomologous end joining, pro-B cell differentiation, phosphorylation, brain development, response to activity, cell population proliferation, telomere maintenance, T cell receptor V(D)J recombination, DNA repair, ectopic germ cell programmed cell death, negative regulation of apoptotic process, T cell differentiation in thymus, B cell lineage commitment, protein phosphorylation, activation of innate immune response, immune system process, innate immune response, immunoglobulin production, negative regulation of immunoglobulin production, positive regulation of immune system process, positive regulation of fibroblast proliferation, spleen development, thymus development, positive regulation of developmental growth, negative regulation of cellular senescence, negative regulation of response to gamma radiation, telomere maintenance, double-strand break repair, cellular response to DNA damage stimulus, intrinsic apoptotic signaling pathway in response to DNA damage, immunoglobulin V(D)J recombination, cell population proliferation, regulation of epithelial cell proliferation, regulation of epithelial cell proliferation, cellular response to DNA damage stimulus, positive regulation of double-strand break repair via nonhomologous end joining, cellular response to DNA damage stimulus, positive regulation of double-strand break repair via nonhomologous end joining

Cell component nucleoplasm, nonhomologous end joining complex, DNA-dependent protein kinase-DNA ligase 4 complex, transcription regulator complex, nucleus, protein-DNA complex, nucleolus, protein-containing complex, nucleus

Encoded by Prkdc

Found in taxon house mouse

Has part(s) PIK-related kinase, FAT, FATC domain, PIK-related kinase, Phosphatidylinositol 3-/4-kinase, catalytic domain, Phosphatidylinositol 3/4-kinase, conserved site, NUC194, DNA-dependent protein kinase catalytic subunit, catalytic domain

Imported from wholeness_audit_2026-05-02

Molecular function enzyme binding, protein serine/threonine kinase activity, ATP binding, DNA binding, DNA-dependent protein kinase activity, protein kinase activity, protein binding, kinase activity, transcription factor binding, nucleotide binding, transferase activity, double-stranded DNA binding, protein domain specific binding, protein serine/threonine kinase activity

External References (3)

Ensembl protein id ENSMUSP00000023352

Refseq protein id NP_035289, XP_006521924, XP_017172381

Uniprot protein id P97313

🏷️ Also known as

en DNA-dependent protein kinase catalytic subunit en DNA-PK catalytic subunit en doxorubicin nephropathy en p460 en Prkdc en Protein kinase, DNA activated, catalytic polypeptide en severe combined immunodeficiency

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Protein kinase, DNA activated, catalytic polypeptide — instance of (P31): protein. UniProt. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Protein kinase, DNA activated, catalytic polypeptide — subclass of (P279): protein. UniProt. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Protein kinase, DNA activated, catalytic polypeptide — UniProt protein ID (P352): P97313. UniProt. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Protein kinase, DNA activated, catalytic polypeptide — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Protein kinase, DNA activated, catalytic polypeptide — part of (P361): Armadillo-type fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Protein kinase, DNA activated, catalytic polypeptide — part of (P361): Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Protein kinase, DNA activated, catalytic polypeptide — part of (P361): Phosphatidylinositol 3-/4-kinase, catalytic domain, protein family. wikidata.org.
[9] ↑ Protein kinase, DNA activated, catalytic polypeptide — part of (P361): DNA-dependent protein kinase catalytic subunit, catalytic domain, protein family. wikidata.org.
[10] ↑ Protein kinase, DNA activated, catalytic polypeptide — part of (P361): PIK-related kinase, FAT family. wikidata.org.
[11] ↑ Protein kinase, DNA activated, catalytic polypeptide — part of (P361): NUC194 domain, protein family. wikidata.org.
[12] ↑ Protein kinase, DNA activated, catalytic polypeptide — part of (P361): PIK-related kinase family. wikidata.org.
[13] ↑ Protein kinase, DNA activated, catalytic polypeptide — part of (P361): FATC domain, protein family. wikidata.org.
[14] ↑ Protein kinase, DNA activated, catalytic polypeptide — part of (P361): Phosphatidylinositol 3/4-kinase, conserved site, protein family. wikidata.org.
[15] ↑ Protein kinase, DNA activated, catalytic polypeptide — has part(s) (P527): PIK-related kinase, FAT. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Protein kinase, DNA activated, catalytic polypeptide — has part(s) (P527): FATC domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Protein kinase, DNA activated, catalytic polypeptide — has part(s) (P527): PIK-related kinase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Protein kinase, DNA activated, catalytic polypeptide — has part(s) (P527): Phosphatidylinositol 3-/4-kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Protein kinase, DNA activated, catalytic polypeptide — has part(s) (P527): Phosphatidylinositol 3/4-kinase, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Protein kinase, DNA activated, catalytic polypeptide — has part(s) (P527): NUC194. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Protein kinase, DNA activated, catalytic polypeptide — has part(s) (P527): DNA-dependent protein kinase catalytic subunit, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Protein kinase, DNA activated, catalytic polypeptide — RefSeq protein ID (P637): NP_035289. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Protein kinase, DNA activated, catalytic polypeptide — RefSeq protein ID (P637): XP_006521924. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Protein kinase, DNA activated, catalytic polypeptide — RefSeq protein ID (P637): XP_017172381. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Protein kinase, DNA activated, catalytic polypeptide — molecular function (P680): enzyme binding. GAPDH mediates nitrosylation of nuclear proteins. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Protein kinase, DNA activated, catalytic polypeptide — molecular function (P680): protein serine/threonine kinase activity. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Protein kinase, DNA activated, catalytic polypeptide is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

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BibTeX

@misc{4ortxyz_protein-kinase-dna-activated-catalytic-polypeptide_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Protein kinase, DNA activated, catalytic polypeptide}}, year = {2026}, url = {https://4ort.xyz/entity/protein-kinase-dna-activated-catalytic-polypeptide}, note = {Accessed: 2026-05-03}}

LLM prompt

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