Protein arginine methyltransferase 2
mammalian protein found in Homo sapiens
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Summary
Protein arginine methyltransferase 2 is a protein[1]. It is known by 9 alternative names across languages and contexts.[2]
Key Facts
- Part of: SH3-like domain superfamily[3], S-adenosyl-L-methionine-dependent methyltransferase[4], Protein arginine N-methyltransferase[5], Methyltransferase small domain, protein family[6], SH3 domain, protein family[7]
- Has part(s): SH3 domain[8], Methyltransferase small domain[9]
- EC enzyme number: 2.1.1.321[10]
- Molecular function: methyltransferase activity[11], transferase activity[12], histone methyltransferase activity[13], protein homodimerization activity[14], progesterone receptor binding[15], transcription coactivator activity[16], signal transducer activity[17], thyroid hormone receptor binding[18], protein binding[19], androgen receptor binding[20], peroxisome proliferator activated receptor binding[21], retinoic acid receptor binding[22], estrogen receptor binding[23], protein-arginine N-methyltransferase activity[24]
- Cell component: cytoplasm[25], cytosol[26], Rb-E2F complex[27], nucleoplasm[28], nucleolus[29], nucleus[30]
- Biological process: developmental cell growth[31], negative regulation of G1/S transition of mitotic cell cycle[32], positive regulation of transcription, DNA-templated[33], methylation[34], positive regulation of apoptotic process[35], regulation of androgen receptor signaling pathway[36], histone methylation[37], negative regulation of transcription, DNA-templated[38], negative regulation of NF-kappaB transcription factor activity[39], signal transduction[40], protein methylation[41], histone arginine methylation[42], peptidyl-arginine N-methylation[43], peptidyl-arginine methylation, to asymmetrical-dimethyl arginine[44]
- Encoded by: PRMT2[45]
- Found in taxon: Homo sapiens[46]