Proteasome 26S subunit, non-ATPase 12

mammalian protein found in Homo sapiens

Protein protein Q21126861

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Summary

Proteasome 26S subunit, non-ATPase 12 is a protein^[1].

Key Facts

Proteasome 26S subunit, non-ATPase 12's instance of is recorded as protein^[2].
Proteasome 26S subunit, non-ATPase 12's UniProt protein ID is recorded as O00232^[3].
Proteasome 26S subunit, non-ATPase 12's part of is recorded as winged helix DNA-binding domain superfamily^[4].
Proteasome 26S subunit, non-ATPase 12's part of is recorded as Winged helix-like DNA-binding domain superfamily^[5].
Proteasome 26S subunit, non-ATPase 12's part of is recorded as 26S Proteasome non-ATPase regulatory subunit 12^[6].
Proteasome 26S subunit, non-ATPase 12's part of is recorded as membrane protein^[7].
Proteasome 26S subunit, non-ATPase 12's part of is recorded as Proteasome component (PCI) domain, protein family^[8].
Proteasome 26S subunit, non-ATPase 12's has part is recorded as Proteasome component (PCI) domain^[9].
Proteasome 26S subunit, non-ATPase 12's RefSeq protein ID is recorded as NP_001303270^[10].
Proteasome 26S subunit, non-ATPase 12's RefSeq protein ID is recorded as NP_002807^[11].
Proteasome 26S subunit, non-ATPase 12's RefSeq protein ID is recorded as NP_777360^[12].
Proteasome 26S subunit, non-ATPase 12's RefSeq protein ID is recorded as XP_024306610^[13].
Proteasome 26S subunit, non-ATPase 12's RefSeq protein ID is recorded as XP_024306611^[14].
Proteasome 26S subunit, non-ATPase 12's molecular function is recorded as protein binding^[15].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as cytoplasm^[16].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as nuclear proteasome complex^[17].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as cytosol^[18].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as membrane^[19].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as proteasome accessory complex^[20].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as proteasome regulatory particle^[21].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as nucleoplasm^[22].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as proteasome regulatory particle, lid subcomplex^[23].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as proteasome complex^[24].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as extracellular exosome^[25].
Proteasome 26S subunit, non-ATPase 12's cell component is recorded as extracellular region^[26].

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Quick Facts

Instance of protein

Part of winged helix DNA-binding domain superfamily, Winged helix-like DNA-binding domain superfamily, 26S Proteasome non-ATPase regulatory subunit 12, membrane protein, Proteasome component (PCI) domain, protein family

Properties

Biological process regulation of cellular amino acid metabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, regulation of mRNA stability, positive regulation of canonical Wnt signaling pathway, protein polyubiquitination, stimulatory C-type lectin receptor signaling pathway, tumor necrosis factor-mediated signaling pathway, MAPK cascade, Fc-epsilon receptor signaling pathway, NIK/NF-kappaB signaling, anaphase-promoting complex-dependent catabolic process, T cell receptor signaling pathway, negative regulation of canonical Wnt signaling pathway, proteasome-mediated ubiquitin-dependent protein catabolic process, Wnt signaling pathway, planar cell polarity pathway, negative regulation of G2/M transition of mitotic cell cycle, protein deubiquitination, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, neutrophil degranulation, transmembrane transport, regulation of transcription from RNA polymerase II promoter in response to hypoxia, post-translational protein modification, regulation of hematopoietic stem cell differentiation, proteasome-mediated ubiquitin-dependent protein catabolic process, interleukin-1-mediated signaling pathway, regulation of mitotic cell cycle phase transition

Cell component cytoplasm, nuclear proteasome complex, cytosol, membrane, proteasome accessory complex, proteasome regulatory particle, nucleoplasm, proteasome regulatory particle, lid subcomplex, proteasome complex, extracellular exosome, extracellular region, secretory granule lumen, ficolin-1-rich granule lumen, membrane, extracellular exosome

Encoded by PSMD12

Found in taxon Homo sapiens

Has part(s) Proteasome component (PCI) domain

Imported from wholeness_audit_2026-05-02

Molecular function protein binding

External References (3)

Ensembl protein id ENSP00000348442, ENSP00000349667, ENSP00000462525, ENSP00000463017

Refseq protein id NP_001303270, NP_002807, NP_777360, XP_024306610, XP_024306611

Uniprot protein id O00232

🏷️ Also known as

en 26S proteasome non-ATPase regulatory subunit 12 en 26S proteasome regulatory subunit p55 en 26S proteasome regulatory subunit RPN5 en Proteasome 26S subunit, non-ATPase 12 en proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 en PSMD12

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Proteasome 26S subunit, non-ATPase 12 — instance of (P31): protein. UniProt. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Proteasome 26S subunit, non-ATPase 12 — UniProt protein ID (P352): O00232. UniProt. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Proteasome 26S subunit, non-ATPase 12 — part of (P361): winged helix DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Proteasome 26S subunit, non-ATPase 12 — part of (P361): Winged helix-like DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Proteasome 26S subunit, non-ATPase 12 — part of (P361): 26S Proteasome non-ATPase regulatory subunit 12. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Proteasome 26S subunit, non-ATPase 12 — part of (P361): membrane protein. wikidata.org.
[8] ↑ Proteasome 26S subunit, non-ATPase 12 — part of (P361): Proteasome component (PCI) domain, protein family. wikidata.org.
[9] ↑ Proteasome 26S subunit, non-ATPase 12 — has part(s) (P527): Proteasome component (PCI) domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Proteasome 26S subunit, non-ATPase 12 — RefSeq protein ID (P637): NP_001303270. Q20641742. Retrieved 2020-05-30. wikidata.org.
[11] ↑ Proteasome 26S subunit, non-ATPase 12 — RefSeq protein ID (P637): NP_002807. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ Proteasome 26S subunit, non-ATPase 12 — RefSeq protein ID (P637): NP_777360. Q20641742. Retrieved 2020-05-30. wikidata.org.
[13] ↑ Proteasome 26S subunit, non-ATPase 12 — RefSeq protein ID (P637): XP_024306610. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ Proteasome 26S subunit, non-ATPase 12 — RefSeq protein ID (P637): XP_024306611. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ Proteasome 26S subunit, non-ATPase 12 — molecular function (P680): protein binding. Large-scale mapping of human protein-protein interactions by mass spectrometry. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): cytoplasm. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): nuclear proteasome complex. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): cytosol. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): membrane. Defining the membrane proteome of NK cells. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): proteasome accessory complex. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): proteasome regulatory particle. cDNA cloning and functional analysis of p44.5 and p55, two regulatory subunits of the 26S proteasome. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): nucleoplasm. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): proteasome regulatory particle, lid subcomplex. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): proteasome complex. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): extracellular exosome. Large-scale proteomics and phosphoproteomics of urinary exosomes. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Proteasome 26S subunit, non-ATPase 12 — cell component (P681): extracellular region. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Proteasome 26S subunit, non-ATPase 12 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Proteasome 26S subunit, non-ATPase 12. Retrieved May 3, 2026, from https://4ort.xyz/entity/proteasome-26s-subunit-non-atpase-12

MLA

“Proteasome 26S subunit, non-ATPase 12.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/proteasome-26s-subunit-non-atpase-12.

BibTeX

@misc{4ortxyz_proteasome-26s-subunit-non-atpase-12_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Proteasome 26S subunit, non-ATPase 12}}, year = {2026}, url = {https://4ort.xyz/entity/proteasome-26s-subunit-non-atpase-12}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Proteasome 26S subunit, non-ATPase 12 — https://4ort.xyz/entity/proteasome-26s-subunit-non-atpase-12 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/proteasome-26s-subunit-non-atpase-12 · Last refreshed: May 3, 2026