Prostaglandin E synthase

mammalian protein found in Homo sapiens
Protein protein Q22676692
Press Enter · cited answer in seconds

Summary

Prostaglandin E synthase is a protein[1]. It is known by 12 alternative names across languages and contexts.[2]

Key Facts

  • Part of: membrane protein[3]
  • Molecular function: glutathione binding[4], isomerase activity[5], prostaglandin-E synthase activity[6], glutathione transferase activity[7]
  • Cell component: cytoplasm[8], integral component of membrane[9], endoplasmic reticulum membrane[10], intracellular membrane-bounded organelle[11], membrane[12], nuclear envelope lumen[13], perinuclear region of cytoplasm[14], mitochondrion[15]
  • Biological process: prostaglandin metabolic process[16], response to cytokine[17], response to organic cyclic compound[18], response to retinoic acid[19], lipid metabolism[20], cyclooxygenase pathway[21], fatty acid metabolic process[22], response to calcium ion[23], response to lipopolysaccharide[24], fatty acid biosynthetic process[25], acute inflammatory response[26], prostaglandin biosynthetic process[27], chronic inflammatory response[28], negative regulation of cell population proliferation[29]
  • Encoded by: PTGES[30]
  • Found in taxon: Homo sapiens[31]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . Structural basis for induced formation of the inflammatory mediator prostaglandin E2.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . UniProt. Retrieved . wikidata.org.
  29. [31] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Prostaglandin E synthase. Retrieved May 3, 2026, from https://4ort.xyz/entity/prostaglandin-e-synthase-q22676692
MLA “Prostaglandin E synthase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/prostaglandin-e-synthase-q22676692.
BibTeX @misc{4ortxyz_prostaglandin-e-synthase-q22676692_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Prostaglandin E synthase}}, year = {2026}, url = {https://4ort.xyz/entity/prostaglandin-e-synthase-q22676692}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Prostaglandin E synthase — https://4ort.xyz/entity/prostaglandin-e-synthase-q22676692 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/prostaglandin-e-synthase-q22676692 · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 11w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → PTGES
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → glutathione binding, isomerase activity, prostaglandin-E synthase activity +3
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 2.5.1.18, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.