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Profilin 1

mammalian protein found in Rattus norvegicus
Class type of: protein Q28561711
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Summary

Profilin 1 is a protein[1].

Key Facts

  • Subclass of: protein[2]
  • Part of: Profilin superfamily[3], Profilin1/2/3, vertebrate[4], Profilin conserved site, protein family[5]
  • Has part(s): Profilin conserved site[6]
  • Molecular function: actin binding[7], signaling receptor binding[8], protein binding[9], phosphatidylinositol-4,5-bisphosphate binding[10]
  • Cell component: nucleus[11], cytoplasm[12], cytoskeleton[13], neuron projection[14], synapse[15], Schaffer collateral - CA1 synapse[16], parallel fiber to Purkinje cell synapse[17], presynapse[18], postsynapse[19], glutamatergic synapse[20]
  • Biological process: neural tube closure[21], regulation of transcription by RNA polymerase II[22], actin polymerization or depolymerization[23]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . UniProt. Retrieved . wikidata.org.
  2. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . wikidata.org.
  5. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] ↑ . Enhanced glomerular profilin gene and protein expression in experimental mesangial proliferative glomerulonephritis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . Activation of DNA synthesis and AP-1 by profilin, an actin-binding protein, via binding to a cell surface receptor in cultured rat mesangial cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . Endothelin-1 mobilizes profilin-1-bound PIP2 in cardiac muscle. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . Enhanced glomerular profilin gene and protein expression in experimental mesangial proliferative glomerulonephritis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . Location of profilin at presynaptic sites in the cerebellar cortex; implication for the regulation of the actin-polymerization state during axonal elongation and synaptogenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . The actin-binding protein profilin I is localized at synaptic sites in an activity-regulated manner. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . The actin-binding protein profilin I is localized at synaptic sites in an activity-regulated manner. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . The actin-binding protein profilin I is localized at synaptic sites in an activity-regulated manner. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . The actin-binding protein profilin I is localized at synaptic sites in an activity-regulated manner. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] ↑ . Enhanced glomerular profilin gene and protein expression in experimental mesangial proliferative glomerulonephritis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Profilin 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/profilin-1-q28561711
MLA “Profilin 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/profilin-1-q28561711.
BibTeX @misc{4ortxyz_profilin-1-q28561711_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Profilin 1}}, year = {2026}, url = {https://4ort.xyz/entity/profilin-1-q28561711}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Profilin 1 — https://4ort.xyz/entity/profilin-1-q28561711 (retrieved 2026-05-03)

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