PR/SET domain 2

mammalian protein found in Homo sapiens
Protein protein Q21123317
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Summary

PR/SET domain 2 is a protein[1]. It is known by 15 alternative names across languages and contexts.[2]

Key Facts

  • Part of: Zinc finger C2H2 superfamily[3], Predicted retinoblastoma binding protein (RIZ)[4], Zinc finger C2H2-type, protein family[5], SET domain, protein family[6]
  • Has part(s): SET domain[7], Zinc finger C2H2-type[8]
  • Molecular function: DNA-binding transcription factor activity[9], methyltransferase activity[10], transferase activity[11], DNA binding[12], zinc ion binding[13], histone-lysine N-methyltransferase activity[14], metal ion binding[15], nucleic acid binding[16], RNA polymerase II transcription regulatory region sequence-specific DNA binding[17], DNA-binding transcription activator activity, RNA polymerase II-specific[18], DNA-binding transcription factor activity, RNA polymerase II-specific[19], chromatin DNA binding[20], sequence-specific DNA binding[21]
  • Cell component: nucleus[22], Golgi apparatus[23]
  • Biological process: histone lysine methylation[24], methylation[25], regulation of transcription, DNA-templated[26], determination of adult lifespan[27], transcription, DNA-templated[28], transcription by RNA polymerase II[29], positive regulation of transcription by RNA polymerase II[30]
  • Encoded by: PRDM2[31]
  • Found in taxon: Homo sapiens[32]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . A census of human transcription factors: function, expression and evolution. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Identification and cloning of the G3B cDNA encoding a 3′ segment of a protein binding to GATA-3. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . UniProt. Retrieved . wikidata.org.
  30. [32] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). PR/SET domain 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/pr-set-domain-2-q21123317
MLA “PR/SET domain 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/pr-set-domain-2-q21123317.
BibTeX @misc{4ortxyz_pr-set-domain-2-q21123317_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{PR/SET domain 2}}, year = {2026}, url = {https://4ort.xyz/entity/pr-set-domain-2-q21123317}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): PR/SET domain 2 — https://4ort.xyz/entity/pr-set-domain-2-q21123317 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 11w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → PRDM2
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → DNA-binding transcription factor activity, methyltransferase activity, transferase activity +13
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 2.1.1.355, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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