Polo-like kinase 2

mammalian protein found in Rattus norvegicus

Protein protein Q28560553

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Summary

Polo-like kinase 2 is a protein^[1].

Key Facts

Polo-like kinase 2's instance of is recorded as protein^[2].
Polo-like kinase 2's subclass of is recorded as protein^[3].
Polo-like kinase 2's UniProt protein ID is recorded as Q9R012^[4].
Polo-like kinase 2's part of is recorded as Protein kinase-like domain superfamily^[5].
Polo-like kinase 2's part of is recorded as POLO box domain superfamily^[6].
Polo-like kinase 2's part of is recorded as First polo-box domain, protein family^[7].
Polo-like kinase 2's part of is recorded as POLO box domain, protein family^[8].
Polo-like kinase 2's part of is recorded as Protein kinase domain, protein family^[9].
Polo-like kinase 2's part of is recorded as Second polo-box domain, protein family^[10].
Polo-like kinase 2's part of is recorded as Protein kinase, ATP binding site, protein family^[11].
Polo-like kinase 2's part of is recorded as Serine/threonine-protein kinase, active site, protein family^[12].
Polo-like kinase 2's has part is recorded as serine/threonine-protein kinase, active site^[13].
Polo-like kinase 2's has part is recorded as POLO box domain^[14].
Polo-like kinase 2's has part is recorded as protein kinase, ATP binding site^[15].
Polo-like kinase 2's has part is recorded as Second polo-box domain^[16].
Polo-like kinase 2's has part is recorded as First polo-box domain^[17].
Polo-like kinase 2's has part is recorded as protein kinase domain^[18].
Polo-like kinase 2's RefSeq protein ID is recorded as NP_114009^[19].
Polo-like kinase 2's molecular function is recorded as nucleotide binding^[20].
Polo-like kinase 2's molecular function is recorded as protein kinase activity^[21].
Polo-like kinase 2's molecular function is recorded as protein serine/threonine kinase activity^[22].
Polo-like kinase 2's molecular function is recorded as protein binding^[23].
Polo-like kinase 2's molecular function is recorded as ATP binding^[24].
Polo-like kinase 2's molecular function is recorded as kinase activity^[25].
Polo-like kinase 2's molecular function is recorded as transferase activity^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Subclass of protein

Part of Protein kinase-like domain superfamily, POLO box domain superfamily, First polo-box domain, protein family, POLO box domain, protein family, Protein kinase domain, protein family, Second polo-box domain, protein family, Protein kinase, ATP binding site, protein family, Serine/threonine-protein kinase, active site, protein family

Properties

Biological process G1/S transition of mitotic cell cycle, mitotic cell cycle, protein phosphorylation, mitotic spindle organization, mitotic cell cycle checkpoint signaling, Ras protein signal transduction, memory, positive regulation of autophagy, phosphorylation, negative regulation of angiogenesis, peptidyl-serine phosphorylation, positive regulation of protein binding, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, Rap protein signal transduction, negative regulation of apoptotic process, positive regulation of protein catabolic process, regulation of centriole replication, regulation of synaptic plasticity, long-term potentiation, long-term depression, negative regulation of dendritic spine development, negative regulation of apoptotic process in bone marrow cell, positive regulation of cell migration involved in sprouting angiogenesis, negative regulation of cellular senescence, G1/S transition of mitotic cell cycle, mitotic cell cycle, mitotic cell cycle checkpoint signaling, regulation of cytokinesis, regulation of synaptic plasticity

Cell component chromatin, intracellular anatomical structure, cytoplasm, centrosome, centriole, cytoskeleton, dendrite, cell projection, spindle pole, nucleus, cytoplasm, centrosome, centriole

Encoded by Plk2

Found in taxon brown rat

Has part(s) serine/threonine-protein kinase, active site, POLO box domain, protein kinase, ATP binding site, Second polo-box domain, First polo-box domain, protein kinase domain

Imported from wholeness_audit_2026-05-02

Molecular function nucleotide binding, protein kinase activity, protein serine/threonine kinase activity, protein binding, ATP binding, kinase activity, transferase activity, ATP-dependent protein binding, protein-containing complex binding, protein serine/threonine kinase activity

External References (3)

Ensembl protein id ENSRNOP00000016768, ENSRNOP00000092527

Refseq protein id NP_114009

Uniprot protein id Q9R012

🏷️ Also known as

en Plk2 en PLK-2 en polo-like kinase 1 en Polo-like kinase 2 en serine/threonine-protein kinase PLK2 en serine/threonine-protein kinase SNK en serum-inducible kinase

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Polo-like kinase 2 — instance of (P31): protein. UniProt. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Polo-like kinase 2 — subclass of (P279): protein. UniProt. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Polo-like kinase 2 — UniProt protein ID (P352): Q9R012. UniProt. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Polo-like kinase 2 — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Polo-like kinase 2 — part of (P361): POLO box domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Polo-like kinase 2 — part of (P361): First polo-box domain, protein family. wikidata.org.
[8] ↑ Polo-like kinase 2 — part of (P361): POLO box domain, protein family. wikidata.org.
[9] ↑ Polo-like kinase 2 — part of (P361): Protein kinase domain, protein family. wikidata.org.
[10] ↑ Polo-like kinase 2 — part of (P361): Second polo-box domain, protein family. wikidata.org.
[11] ↑ Polo-like kinase 2 — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[12] ↑ Polo-like kinase 2 — part of (P361): Serine/threonine-protein kinase, active site, protein family. wikidata.org.
[13] ↑ Polo-like kinase 2 — has part(s) (P527): serine/threonine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Polo-like kinase 2 — has part(s) (P527): POLO box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Polo-like kinase 2 — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Polo-like kinase 2 — has part(s) (P527): Second polo-box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Polo-like kinase 2 — has part(s) (P527): First polo-box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Polo-like kinase 2 — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Polo-like kinase 2 — RefSeq protein ID (P637): NP_114009. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Polo-like kinase 2 — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Polo-like kinase 2 — molecular function (P680): protein kinase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Polo-like kinase 2 — molecular function (P680): protein serine/threonine kinase activity. GOA. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Polo-like kinase 2 — molecular function (P680): protein binding. Requirement for Plk2 in Orchestrated Ras and Rap Signaling, Homeostatic Structural Plasticity, and Memory. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Polo-like kinase 2 — molecular function (P680): ATP binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Polo-like kinase 2 — molecular function (P680): kinase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Polo-like kinase 2 — molecular function (P680): transferase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Polo-like kinase 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Polo-like kinase 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/polo-like-kinase-2-q28560553

MLA

“Polo-like kinase 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/polo-like-kinase-2-q28560553.

BibTeX

@misc{4ortxyz_polo-like-kinase-2-q28560553_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Polo-like kinase 2}}, year = {2026}, url = {https://4ort.xyz/entity/polo-like-kinase-2-q28560553}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Polo-like kinase 2 — https://4ort.xyz/entity/polo-like-kinase-2-q28560553 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/polo-like-kinase-2-q28560553 · Last refreshed: May 3, 2026