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Phospholamban

mammalian protein found in Homo sapiens
Protein Protein Q410105

Facts

7 properties
Instance of
protein
Part of
Phospholamban, Phospholamban (Ca2+-channel and Ca2+-ATPase Regulator)[2][3]
Biological process
Notch signaling pathway, regulation of ryanodine-sensitive calcium-release channel activity, negative regulation of calcium ion binding, regulation of cardiac conduction, regulation of calcium ion transport, negative regulation of catalytic activity, regulation of heart contraction, regulation of cytosolic calcium ion concentration, cardiac muscle tissue development, negative regulation of heart contraction, response to testosterone, regulation of the force of heart contraction, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, negative regulation of ATP-dependent activity, regulation of ATPase-coupled calcium transmembrane transporter activity, regulation of calcium ion import, response to zinc ion, cellular calcium ion homeostasis, regulation of relaxation of cardiac muscle, negative regulation of calcium ion transmembrane transporter activity, blood circulation, negative regulation of heart rate, negative regulation of calcium ion import, response to insulin, regulation of cardiac muscle cell contraction, negative regulation of ATPase-coupled calcium transmembrane transporter activity, negative regulation of calcium ion transport, adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process, regulation of cardiac muscle cell membrane potential, regulation of the force of heart contraction by cardiac conduction, regulation of relaxation of muscle, negative regulation of calcium ion import into sarcoplasmic reticulum, protein homooligomerization, regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, relaxation of cardiac muscle, calcium ion transport, negative regulation of ATPase-coupled calcium transmembrane transporter activity, negative regulation of calcium ion import into sarcoplasmic reticulum
Cell component
integral component of membrane, vesicle, endoplasmic reticulum membrane, membrane, mitochondrial membranes, sarcoplasmic reticulum, endoplasmic reticulum, mitochondrion, sarcoplasmic reticulum membrane, perinuclear region of cytoplasm, calcium ion-transporting ATPase complex, mitochondrion, protein-containing complex[11][12][13][14][15][16][17][18]
Encoded by
PLN
Found in taxon
Homo sapiens
Molecular function
enzyme inhibitor activity, ATPase binding, calcium channel regulator activity, protein binding, ATPase inhibitor activity, identical protein binding, protein homodimerization activity[4][5][6][7][8][9][10]
🏷️ Also known as
en cardiac phospholamban en Phospholamban en PLN es Fosfolambán es PLN fr Phospholambane id Fosfolamban ja ホスホランバン pt Fosfolambano uk PLN (ген)
🔖 Identifiers · 9
OpenAlex ID
C17137333
Ensembl protein ID
ENSP00000350132
Exact match
purl.uniprot.org
Freebase ID
/m/071l16
Microsoft Academic ID (discontinued)
17137333
PDB structure ID
1PLP, 1ZLL, 2HYN
RefSeq protein ID
NP_002658
Transporter Classification Database ID
1.A.50.1.1
UniProt protein ID
P26678

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🔗 Connections
Cell component 5
mitochondrion, mitochondrion, endoplasmic reticulum, vesicle, sarcoplasmic reticulum
Biological process 2
blood circulation, Notch signaling pathway
Found in taxon 1
Homo sapiens
Instance of 1
protein
Molecular function 1
protein binding
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Summary

Phospholamban is a protein[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [3] ↑ . Retrieved . wikidata.org.
  3. [4] ↑ . Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [6] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [7] ↑ . Widespread macromolecular interaction perturbations in human genetic disorders. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Phospholamban. Retrieved November 12, 2026, from https://4ort.xyz/entity/phospholamban
MLA “Phospholamban.” 4ort.xyz Knowledge Graph, 4ort.xyz, 12 Nov. 2026, https://4ort.xyz/entity/phospholamban.
BibTeX @misc{4ortxyz_phospholamban_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Phospholamban}}, year = {2026}, url = {https://4ort.xyz/entity/phospholamban}, note = {Accessed: 2026-11-12}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Phospholamban — https://4ort.xyz/entity/phospholamban (retrieved 2026-11-12)

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