Phosphodiesterase 4A

mammalian protein found in Homo sapiens
Protein protein Q21117805
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Phosphodiesterase 4A

Summary

Phosphodiesterase 4A is a protein[1].

Key Facts

  • Phosphodiesterase 4A's instance of is recorded as protein[2].
  • Phosphodiesterase 4A's physically interacts with is recorded as ibudilast[3].
  • Phosphodiesterase 4A's physically interacts with is recorded as rolipram[4].
  • Phosphodiesterase 4A's physically interacts with is recorded as YM976[5].
  • Phosphodiesterase 4A's physically interacts with is recorded as dyphylline[6].
  • Phosphodiesterase 4A's physically interacts with is recorded as crisaborole[7].
  • Phosphodiesterase 4A's physically interacts with is recorded as ibudilast[8].
  • Phosphodiesterase 4A's physically interacts with is recorded as tetomilast[9].
  • Phosphodiesterase 4A's physically interacts with is recorded as flavoxate hydrochloride[10].
  • Phosphodiesterase 4A is part of 3'5'-cyclic nucleotide phosphodiesterase[11].
  • Phosphodiesterase 4A is part of 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily[12].
  • Phosphodiesterase 4A is part of 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, protein family[13].
  • Phosphodiesterase 4A is part of HD/PDEase domain, protein family[14].
  • Phosphodiesterase 4A is part of 3'5'-cyclic nucleotide phosphodiesterase, conserved site, protein family[15].
  • Phosphodiesterase 4A comprises 3'5'-cyclic nucleotide phosphodiesterase, conserved site[16].
  • Phosphodiesterase 4A comprises 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain[17].
  • Phosphodiesterase 4A comprises HD/PDEase domain[18].
  • Phosphodiesterase 4A's molecular function is recorded as phosphoric diester hydrolase activity[19].
  • Phosphodiesterase 4A's molecular function is recorded as cAMP binding[20].
  • Phosphodiesterase 4A's molecular function is recorded as protein binding[21].
  • Phosphodiesterase 4A's molecular function is recorded as hydrolase activity[22].
  • Phosphodiesterase 4A's molecular function is recorded as 3',5'-cyclic-nucleotide phosphodiesterase activity[23].
  • Phosphodiesterase 4A's molecular function is recorded as metal ion binding[24].
  • Phosphodiesterase 4A's molecular function is recorded as 3',5'-cyclic-AMP phosphodiesterase activity[25].
  • Phosphodiesterase 4A's molecular function is recorded as 3',5'-cyclic-AMP phosphodiesterase activity[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [5] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  5. [6] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  6. [7] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  7. [8] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  8. [9] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  9. [10] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  10. [11] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . wikidata.org.
  13. [14] . wikidata.org.
  14. [15] . wikidata.org.
  15. [16] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Molecular cloning, genomic positioning, promoter identification, and characterization of the novel cyclic amp-specific phosphodiesterase PDE4A10. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Phosphodiesterase 4A. Retrieved May 3, 2026, from https://4ort.xyz/entity/phosphodiesterase-4a
MLA “Phosphodiesterase 4A.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/phosphodiesterase-4a.
BibTeX @misc{4ortxyz_phosphodiesterase-4a_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Phosphodiesterase 4A}}, year = {2026}, url = {https://4ort.xyz/entity/phosphodiesterase-4a}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 4w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from
    Encoded by PDE4A
    Wikidata description mammalian protein found in Homo sapiens
    Molecular function phosphoric diester hydrolase activity, cAMP binding, protein binding +7
    + 12 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 3.1.4.53, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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