Phosphatase and tensin homolog

tumor suppressor gene
Protein protein Q416356
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Phosphatase and tensin homolog

Summary

Phosphatase and tensin homolog is a protein[1]. It ranks in the top 9% of protein entities by monthly Wikipedia readership (64 views/month).[2]

Key Facts

  • Phosphatase and tensin homolog's instance of is recorded as protein[3].
  • Phosphatase and tensin homolog is part of Protein-tyrosine phosphatase-like[4].
  • Phosphatase and tensin homolog is part of Bifunctional phosphatidylinositol trisphosphate phosphatase/dual specificity phosphatase PTEN[5].
  • Phosphatase and tensin homolog is part of Tensin phosphatase, C2 domain, protein family[6].
  • Phosphatase and tensin homolog is part of Tensin-type phosphatase domain, protein family[7].
  • Phosphatase and tensin homolog is part of Dual specificity phosphatase[8].
  • Phosphatase and tensin homolog is part of Protein-tyrosine phosphatase, catalytic domain, protein family[9].
  • Phosphatase and tensin homolog is part of Protein-tyrosine phosphatase, active site, protein family[10].
  • Phosphatase and tensin homolog's Commons category is recorded as PTEN phosphohydrolase[11].
  • Phosphatase and tensin homolog comprises Tensin-type phosphatase domain[12].
  • Phosphatase and tensin homolog comprises Protein-tyrosine phosphatase, catalytic[13].
  • Phosphatase and tensin homolog comprises Protein-tyrosine phosphatase, active site[14].
  • Phosphatase and tensin homolog comprises Tensin phosphatase, C2 domain[15].
  • Phosphatase and tensin homolog's molecular function is recorded as phosphoprotein phosphatase activity[16].
  • Phosphatase and tensin homolog's molecular function is recorded as phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity[17].
  • Phosphatase and tensin homolog's molecular function is recorded as phosphatidylinositol-3-phosphatase activity[18].
  • Phosphatase and tensin homolog's molecular function is recorded as protein serine/threonine phosphatase activity[19].
  • Phosphatase and tensin homolog's molecular function is recorded as protein tyrosine phosphatase activity[20].
  • Phosphatase and tensin homolog's molecular function is recorded as protein tyrosine/serine/threonine phosphatase activity[21].
  • Phosphatase and tensin homolog's molecular function is recorded as enzyme binding[22].
  • Phosphatase and tensin homolog's molecular function is recorded as platelet-derived growth factor receptor binding[23].
  • Phosphatase and tensin homolog's molecular function is recorded as protein binding[24].
  • Phosphatase and tensin homolog's molecular function is recorded as protein kinase binding[25].
  • Phosphatase and tensin homolog's molecular function is recorded as phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity[26].
  • Phosphatase and tensin homolog's molecular function is recorded as anaphase-promoting complex binding[27].

Why It Matters

Phosphatase and tensin homolog ranks in the top 9% of protein entities by monthly Wikipedia readership (64 views/month).[2] It has Wikipedia articles in 14 language editions, a strong signal of global cultural recognition.[28] It is known by 20 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . wikidata.org.
  5. [7] . wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . wikidata.org.
  9. [11] . wikidata.org.
  10. [12] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . Critical role for Daxx in regulating Mdm2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . Rak functions as a tumor suppressor by regulating PTEN protein stability and function. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Phosphatase and tensin homolog. Retrieved May 3, 2026, from https://4ort.xyz/entity/phosphatase-and-tensin-homolog
MLA “Phosphatase and tensin homolog.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/phosphatase-and-tensin-homolog.
BibTeX @misc{4ortxyz_phosphatase-and-tensin-homolog_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Phosphatase and tensin homolog}}, year = {2026}, url = {https://4ort.xyz/entity/phosphatase-and-tensin-homolog}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Phosphatase and tensin homolog — https://4ort.xyz/entity/phosphatase-and-tensin-homolog (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/phosphatase-and-tensin-homolog · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 4w ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Ec enzyme number ['3.1.3.16', '3.1.3.48', '3.1.3.67']
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 3.1.3.16, [[:toollabs:quickstatements/#/batch/261446|batch #261446]]"
  2. 5w ago · Dirac · 2026-07-20 view diff on Wikidata ↗
    Molecular function phosphoprotein phosphatase activity, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity, phosphatidylinositol-3-phosphatase activity +18
    Part of
    Cell component cytoplasm, postsynaptic membrane, extracellular region +14
    Instance of protein
    + 9 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P18]]: Pten.jpg, [[:toollabs:quickstatements/#/batch/261337|batch #261337]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.