parathyroid hormone

mammalian protein found in Homo sapiens
Protein protein Q202476
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Summary

parathyroid hormone is a protein[1]. It ranks in the top 3% of protein entities by monthly Wikipedia readership (2,192 views/month).[2]

Key Facts

  • Instance of: hormone[3]
  • Part of: Parathyroid hormone[4]
  • Commons category: Parathyroid hormone[5]
  • Molecular function: transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding[6], hormone activity[7], parathyroid hormone receptor binding[8], type 1 parathyroid hormone receptor binding[9], protein N-terminus binding[10], receptor ligand activity[11], peptide hormone receptor binding[12], DNA-binding transcription factor activity, RNA polymerase II-specific[13], protein binding[14]
  • Cell component: intracellular anatomical structure[15], extracellular region[16], extracellular space[17]
  • Biological process: positive regulation of signal transduction[18], positive regulation of cell proliferation in bone marrow[19], positive regulation of osteoclast proliferation[20], response to fibroblast growth factor[21], hormone-mediated apoptotic signaling pathway[22], cAMP metabolic process[23], response to ethanol[24], response to parathyroid hormone[25], skeletal system development[26], positive regulation of ossification[27], response to lead ion[28], response to nutrient levels[29], G protein-coupled receptor signaling pathway[30], response to vitamin D[31]

Why It Matters

parathyroid hormone has Wikipedia articles in 27 language editions, a strong signal of global cultural recognition.[32] It is known by 75 alternative names across languages and contexts.[33]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . Control of the SOST bone enhancer by PTH using MEF2 transcription factors. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . Comparison of rat and human parathyroid hormone 2 (PTH2) receptor activation: PTH is a low potency partial agonist at the rat PTH2 receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . Control of the SOST bone enhancer by PTH using MEF2 transcription factors. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . In vivo regulation of apoptosis in metaphyseal trabecular bone of young rats by synthetic human parathyroid hormone (1-34) fragment. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Human osteoclast-like cells are formed from peripheral blood mononuclear cells in a coculture with SaOS-2 cells transfected with the parathyroid hormone (PTH)/PTH-related protein receptor gene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . In vivo regulation of apoptosis in metaphyseal trabecular bone of young rats by synthetic human parathyroid hormone (1-34) fragment. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [32] ↑ . Wikidata sitelinks. wikidata.org.
  3. [33] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). parathyroid hormone. Retrieved October 15, 2026, from https://4ort.xyz/entity/parathyroid-hormone
MLA “parathyroid hormone.” 4ort.xyz Knowledge Graph, 4ort.xyz, 15 Oct. 2026, https://4ort.xyz/entity/parathyroid-hormone.
BibTeX @misc{4ortxyz_parathyroid-hormone_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{parathyroid hormone}}, year = {2026}, url = {https://4ort.xyz/entity/parathyroid-hormone}, note = {Accessed: 2026-10-15}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 21w ago · Twofivesixbot bot · 2026-05-18 view diff on Wikidata ↗
    Cell component → intracellular anatomical structure, extracellular region, extracellular space
    Instance of → —
    Molecular function → transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding, hormone activity, parathyroid hormone receptor binding +8
    Biological process → positive regulation of signal transduction, positive regulation of cell proliferation in bone marrow, positive regulation of osteoclast proliferation +39
    + 8 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|7 */ Yso id: 25171, mv to monolingual text names on YSO statements"
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