Pancreas specific transcription factor, 1a

mammalian protein found in Mus musculus
Protein protein Q21987932
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Summary

Pancreas specific transcription factor, 1a is a protein[1].

Key Facts

  • Pancreas specific transcription factor, 1a's instance of is recorded as protein[2].
  • Pancreas specific transcription factor, 1a's subclass of is recorded as protein[3].
  • Pancreas specific transcription factor, 1a's UniProt protein ID is recorded as Q9QX98[4].
  • Pancreas specific transcription factor, 1a's part of is recorded as Helix-loop-helix DNA-binding domain superfamily[5].
  • Pancreas specific transcription factor, 1a's part of is recorded as Myc-type, basic helix-loop-helix (bHLH) domain, protein family[6].
  • Pancreas specific transcription factor, 1a's has part is recorded as Myc-type, basic helix-loop-helix (bHLH) domain[7].
  • Pancreas specific transcription factor, 1a's RefSeq protein ID is recorded as NP_061279[8].
  • Pancreas specific transcription factor, 1a's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding[9].
  • Pancreas specific transcription factor, 1a's molecular function is recorded as sequence-specific DNA binding[10].
  • Pancreas specific transcription factor, 1a's molecular function is recorded as protein dimerization activity[11].
  • Pancreas specific transcription factor, 1a's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific[12].
  • Pancreas specific transcription factor, 1a's molecular function is recorded as chromatin binding[13].
  • Pancreas specific transcription factor, 1a's molecular function is recorded as E-box binding[14].
  • Pancreas specific transcription factor, 1a's molecular function is recorded as protein binding[15].
  • Pancreas specific transcription factor, 1a's molecular function is recorded as DNA binding[16].
  • Pancreas specific transcription factor, 1a's cell component is recorded as cytosol[17].
  • Pancreas specific transcription factor, 1a's cell component is recorded as intracellular anatomical structure[18].
  • Pancreas specific transcription factor, 1a's cell component is recorded as nucleoplasm[19].
  • Pancreas specific transcription factor, 1a's cell component is recorded as nucleus[20].
  • Pancreas specific transcription factor, 1a's cell component is recorded as transcription regulator complex[21].
  • Pancreas specific transcription factor, 1a's cell component is recorded as cytoplasm[22].
  • Pancreas specific transcription factor, 1a's biological process is recorded as cell differentiation[23].
  • Pancreas specific transcription factor, 1a's biological process is recorded as cell fate commitment[24].
  • Pancreas specific transcription factor, 1a's biological process is recorded as retina layer formation[25].
  • Pancreas specific transcription factor, 1a's biological process is recorded as hindbrain development[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . UniProt. Retrieved . wikidata.org.
  2. [3] ↑ . UniProt. Retrieved . wikidata.org.
  3. [4] ↑ . UniProt. Retrieved . wikidata.org.
  4. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . Q20641742. Retrieved . wikidata.org.
  8. [9] ↑ . Isolation of the murine ribonuclease geneRib-1: structure and tissue specific expression of pancreas and parotid gland. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . Ptf1a directly controls expression of immunoglobulin superfamily molecules Nephrin and Neph3 in the developing central nervous system. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . RNA profiling and chromatin immunoprecipitation-sequencing reveal that PTF1a stabilizes pancreas progenitor identity via the control of MNX1/HLXB9 and a network of other transcription factors. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] ↑ . Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] ↑ . The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] ↑ . Ptf1a determines horizontal and amacrine cell fates during mouse retinal development. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] ↑ . p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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BibTeX @misc{4ortxyz_pancreas-specific-transcription-factor-1a_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Pancreas specific transcription factor, 1a}}, year = {2026}, url = {https://4ort.xyz/entity/pancreas-specific-transcription-factor-1a}, note = {Accessed: 2026-05-03}}
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