Paired box 8

mammalian protein found in Mus musculus
Protein protein Q21988403
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Paired box 8

Summary

Paired box 8 is a protein[1].

Key Facts

  • Paired box 8's instance of is recorded as protein[2].
  • Paired box 8's subclass of is recorded as protein[3].
  • Paired box 8's UniProt protein ID is recorded as Q00288[4].
  • Paired box 8's part of is recorded as Homeobox-like domain superfamily[5].
  • Paired box 8's part of is recorded as Winged helix-like DNA-binding domain superfamily[6].
  • Paired box 8's part of is recorded as Paired-box protein 2 C-terminal domain, protein family[7].
  • Paired box 8's part of is recorded as Paired domain, protein family[8].
  • Paired box 8's has part is recorded as Paired domain[9].
  • Paired box 8's has part is recorded as Paired-box protein 2 C-terminal[10].
  • Paired box 8's RefSeq protein ID is recorded as NP_035170[11].
  • Paired box 8's molecular function is recorded as DNA binding[12].
  • Paired box 8's molecular function is recorded as DNA-binding transcription factor activity[13].
  • Paired box 8's molecular function is recorded as protein binding[14].
  • Paired box 8's molecular function is recorded as RNA polymerase II core promoter sequence-specific DNA binding[15].
  • Paired box 8's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding[16].
  • Paired box 8's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific[17].
  • Paired box 8's molecular function is recorded as sequence-specific DNA binding[18].
  • Paired box 8's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding[19].
  • Paired box 8's molecular function is recorded as RNA polymerase II core promoter sequence-specific DNA binding[20].
  • Paired box 8's cell component is recorded as transcription regulator complex[21].
  • Paired box 8's cell component is recorded as nucleoplasm[22].
  • Paired box 8's cell component is recorded as nucleus[23].
  • Paired box 8's biological process is recorded as regulation of apoptotic process[24].
  • Paired box 8's biological process is recorded as pronephros development[25].
  • Paired box 8's biological process is recorded as regulation of metanephric nephron tubule epithelial cell differentiation[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . wikidata.org.
  7. [8] . wikidata.org.
  8. [9] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . Q20641742. Retrieved . wikidata.org.
  11. [12] . PAX8-mediated activation of the wt1 tumor suppressor gene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . Pax genes and their role in organogenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Pax genes and their role in organogenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Nephric lineage specification by Pax2 and Pax8. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Nephric lineage specification by Pax2 and Pax8. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Paired box 8. Retrieved May 3, 2026, from https://4ort.xyz/entity/paired-box-8-q21988403
MLA “Paired box 8.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/paired-box-8-q21988403.
BibTeX @misc{4ortxyz_paired-box-8-q21988403_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Paired box 8}}, year = {2026}, url = {https://4ort.xyz/entity/paired-box-8-q21988403}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Paired box 8 — https://4ort.xyz/entity/paired-box-8-q21988403 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/paired-box-8-q21988403 · Last refreshed: