paired box 8

mammalian protein found in Homo sapiens
Protein protein Q21120164
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paired box 8

Summary

paired box 8 is a protein[1]. It draws 19 Wikipedia views per month (protein category, ranking #141 of 987).[2]

Key Facts

  • paired box 8's instance of is recorded as protein[3].
  • paired box 8's UniProt protein ID is recorded as Q06710[4].
  • paired box 8's HGNC ID is recorded as 8622[5].
  • paired box 8's part of is recorded as Homeobox-like domain superfamily[6].
  • paired box 8's part of is recorded as Winged helix-like DNA-binding domain superfamily[7].
  • paired box 8's part of is recorded as Paired-box protein 2 C-terminal domain, protein family[8].
  • paired box 8's part of is recorded as Paired domain, protein family[9].
  • paired box 8's MeSH descriptor ID is recorded as D000072636[10].
  • paired box 8's has part is recorded as Paired domain[11].
  • paired box 8's has part is recorded as Paired-box protein 2 C-terminal[12].
  • paired box 8's RefSeq protein ID is recorded as NP_003457[13].
  • paired box 8's RefSeq protein ID is recorded as NP_039246[14].
  • paired box 8's RefSeq protein ID is recorded as NP_039247[15].
  • paired box 8's RefSeq protein ID is recorded as NP_054698[16].
  • paired box 8's PDB structure ID is recorded as 2K27[17].
  • paired box 8's Freebase ID is recorded as /m/03gwpx4[18].
  • paired box 8's MeSH tree code is recorded as D12.776.260.645.906[19].
  • paired box 8's MeSH tree code is recorded as D12.776.930.700.906[20].
  • paired box 8's molecular function is recorded as DNA binding[21].
  • paired box 8's molecular function is recorded as sequence-specific DNA binding[22].
  • paired box 8's molecular function is recorded as DNA-binding transcription factor activity[23].
  • paired box 8's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific[24].
  • paired box 8's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding[25].
  • paired box 8's molecular function is recorded as thyroid-stimulating hormone receptor activity[26].
  • paired box 8's molecular function is recorded as protein binding[27].

Why It Matters

paired box 8 draws 19 Wikipedia views per month (protein category, ranking #141 of 987).[2] It has Wikipedia articles in 6 language editions, a strong signal of global cultural recognition.[28] It is known by 3 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . Q905695. Retrieved . wikidata.org.
  3. [5] . wikidata.org.
  4. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . wikidata.org.
  9. [11] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . Q20641742. Retrieved . wikidata.org.
  12. [14] . Q20641742. Retrieved . wikidata.org.
  13. [15] . Q20641742. Retrieved . wikidata.org.
  14. [16] . Q20641742. Retrieved . wikidata.org.
  15. [17] . Q905695. Retrieved . wikidata.org.
  16. [18] . wikidata.org.
  17. [19] . wikidata.org.
  18. [20] . wikidata.org.
  19. [21] . PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . Structural defects of a Pax8 mutant that give rise to congenital hypothyroidism. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). paired box 8. Retrieved May 3, 2026, from https://4ort.xyz/entity/paired-box-8
MLA “paired box 8.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/paired-box-8.
BibTeX @misc{4ortxyz_paired-box-8_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{paired box 8}}, year = {2026}, url = {https://4ort.xyz/entity/paired-box-8}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): paired box 8 — https://4ort.xyz/entity/paired-box-8 (retrieved 2026-05-03)

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