P21 (RAC1) activated kinase 3

mammalian protein found in Homo sapiens

Protein protein Q21109710

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Summary

P21 (RAC1) activated kinase 3 is a protein^[1]. It draws 84 Wikipedia views per month (protein category, ranking #150 of 987).^[2]

Key Facts

P21 (RAC1) activated kinase 3's instance of is recorded as protein^[3].
P21 (RAC1) activated kinase 3 is part of CRIB domain superfamily^[4].
P21 (RAC1) activated kinase 3 is part of Serine/threonine-protein kinase PAK2/3^[5].
P21 (RAC1) activated kinase 3 is part of Protein kinase-like domain superfamily^[6].
P21 (RAC1) activated kinase 3 is part of p21 activated kinase binding domain, protein family^[7].
P21 (RAC1) activated kinase 3 is part of CRIB domain, protein family^[8].
P21 (RAC1) activated kinase 3 is part of p21-activated kinase 3, catalytic domain, protein family^[9].
P21 (RAC1) activated kinase 3 is part of Protein kinase domain, protein family^[10].
P21 (RAC1) activated kinase 3 is part of Protein kinase, ATP binding site, protein family^[11].
P21 (RAC1) activated kinase 3 is part of Serine/threonine-protein kinase, active site, protein family^[12].
P21 (RAC1) activated kinase 3 comprises serine/threonine-protein kinase, active site^[13].
P21 (RAC1) activated kinase 3 comprises protein kinase domain^[14].
P21 (RAC1) activated kinase 3 comprises protein kinase, ATP binding site^[15].
P21 (RAC1) activated kinase 3 comprises CRIB domain^[16].
P21 (RAC1) activated kinase 3 comprises p21 activated kinase binding domain^[17].
P21 (RAC1) activated kinase 3 comprises p21-activated kinase 3, catalytic domain^[18].
P21 (RAC1) activated kinase 3's molecular function is recorded as transferase activity^[19].
P21 (RAC1) activated kinase 3's molecular function is recorded as nucleotide binding^[20].
P21 (RAC1) activated kinase 3's molecular function is recorded as protein kinase activity^[21].
P21 (RAC1) activated kinase 3's molecular function is recorded as SH3 domain binding^[22].
P21 (RAC1) activated kinase 3's molecular function is recorded as metal ion binding^[23].
P21 (RAC1) activated kinase 3's molecular function is recorded as kinase activity^[24].
P21 (RAC1) activated kinase 3's molecular function is recorded as protein binding^[25].
P21 (RAC1) activated kinase 3's molecular function is recorded as catalytic activity^[26].
P21 (RAC1) activated kinase 3's molecular function is recorded as GTPase binding^[27].

Why It Matters

P21 (RAC1) activated kinase 3 draws 84 Wikipedia views per month (protein category, ranking #150 of 987).^[2]

⭐ Popularity Graph

13/100 long tail

📈 Wikipedia Views · last 38h

87/mo 558/yr

Quick Facts

Instance of protein

Part of CRIB domain superfamily, Serine/threonine-protein kinase PAK2/3, Protein kinase-like domain superfamily, p21 activated kinase binding domain, protein family, CRIB domain, protein family, p21-activated kinase 3, catalytic domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Serine/threonine-protein kinase, active site, protein family

Properties

Biological process regulation of neuron projection development, phosphorylation, ephrin receptor signaling pathway, dendrite development, T cell costimulation, synapse organization, cellular response to organic cyclic compound, stimulatory C-type lectin receptor signaling pathway, multicellular organism development, protein phosphorylation, regulation of actin filament polymerization, positive regulation of neuron apoptotic process, dendritic spine development, positive regulation of DNA biosynthetic process, metabolism, T cell receptor signaling pathway, positive regulation of dendritic spine morphogenesis, MAPK cascade, regulation of actin cytoskeleton organization, positive regulation of fibroblast migration, dendritic spine morphogenesis, Rho protein signal transduction, regulation of mitotic cell cycle, axonogenesis, cell migration, stress-activated protein kinase signaling cascade, regulation of axonogenesis, regulation of apoptotic process, signal transduction, activation of protein kinase activity, regulation of apoptotic process, regulation of MAPK cascade

Cell component cytoplasm, cytosol, endosome, plasma membrane, postsynaptic density, glutamatergic synapse

Ec enzyme number 2.7.11.1

Encoded by PAK3

Found in taxon Homo sapiens

Has part(s) serine/threonine-protein kinase, active site, protein kinase domain, protein kinase, ATP binding site, CRIB domain, p21 activated kinase binding domain, p21-activated kinase 3, catalytic domain

Molecular function transferase activity, nucleotide binding, protein kinase activity, SH3 domain binding, metal ion binding, kinase activity, protein binding, catalytic activity, GTPase binding, ATP binding, MAP kinase kinase activity, protein serine/threonine kinase activity, protein serine/threonine kinase activity

External References (5)

Ensembl protein id ENSP00000262836, ENSP00000353864, ENSP00000361077, ENSP00000361080, ENSP00000389172, ENSP00000401982, ENSP00000410853, ENSP00000428921, ENSP00000429113, ENSP00000405642, ENSP00000484798

Freebase id /m/03gwy7x

Pdb structure id 1EES

Refseq protein id NP_001121638, NP_001121639, NP_001121640, NP_001121644, NP_001121645, NP_001311254, NP_001311255, NP_001311256, NP_001311257, NP_001311258, NP_001311259, NP_001311260, NP_001311261, NP_001311262, NP_001311263, NP_002569, XP_005262189, XP_005262190, XP_006724717, XP_006724718, XP_011529264, XP_011529269, XP_011529270, XP_011529271, XP_011529273, XP_016885046, XP_016885047, XP_016885048, XP_016885049, XP_016885050, XP_016885051, XP_016885052

Uniprot protein id O75914

🌐 Available in 4 languages

enPAK3 cyPAK3 deP21-aktivierte Kinase 3 ukPAK3

🏷️ Also known as

en adriamycin resistance-associated en Beta-PAK en oligophrenin-3 en p21-activated kinase 3 en p21 (CDKN1A)-activated kinase 3 en p21 protein (Cdc42/Rac)-activated kinase 3 en P21 (RAC1) activated kinase 3 en PAK-3 en PAK3 en serine/threonine-protein kinase PAK 3 nl P21

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). P21 (RAC1) activated kinase 3. Retrieved October 16, 2026, from https://4ort.xyz/entity/p21-rac1-activated-kinase-3

MLA

“P21 (RAC1) activated kinase 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 16 Oct. 2026, https://4ort.xyz/entity/p21-rac1-activated-kinase-3.

BibTeX

@misc{4ortxyz_p21-rac1-activated-kinase-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{P21 (RAC1) activated kinase 3}}, year = {2026}, url = {https://4ort.xyz/entity/p21-rac1-activated-kinase-3}, note = {Accessed: 2026-10-16}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): P21 (RAC1) activated kinase 3 — https://4ort.xyz/entity/p21-rac1-activated-kinase-3 (retrieved 2026-10-16)

Canonical URL: https://4ort.xyz/entity/p21-rac1-activated-kinase-3 · Last refreshed: October 16, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗

Imported from → —

Encoded by → PAK3

Wikidata description → mammalian protein found in Homo sapiens

Molecular function → transferase activity, nucleotide binding, protein kinase activity +10

+ 12 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ Ec enzyme number: 2.7.11.1, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"

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