O-6-methylguanine-DNA methyltransferase

mammalian protein found in Mus musculus

Protein protein Q21985779

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O-6-methylguanine-DNA methyltransferase

Summary

O-6-methylguanine-DNA methyltransferase is a protein^[1].

Key Facts

O-6-methylguanine-DNA methyltransferase's instance of is recorded as protein^[2].
O-6-methylguanine-DNA methyltransferase's subclass of is recorded as protein^[3].
O-6-methylguanine-DNA methyltransferase's UniProt protein ID is recorded as P26187^[4].
O-6-methylguanine-DNA methyltransferase's part of is recorded as Methylated DNA-protein cysteine methyltransferase domain superfamily^[5].
O-6-methylguanine-DNA methyltransferase's part of is recorded as Winged helix-like DNA-binding domain superfamily^[6].
O-6-methylguanine-DNA methyltransferase's part of is recorded as Methylated DNA-protein cysteine methyltransferase, DNA binding domain^[7].
O-6-methylguanine-DNA methyltransferase's part of is recorded as Methylguanine DNA methyltransferase, ribonuclease-like domain, protein family^[8].
O-6-methylguanine-DNA methyltransferase's part of is recorded as Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding domain, protein family^[9].
O-6-methylguanine-DNA methyltransferase's part of is recorded as Methylated-DNA-[protein]-cysteine S-methyltransferase, active site, protein family^[10].
O-6-methylguanine-DNA methyltransferase's has part is recorded as Methylguanine DNA methyltransferase, ribonuclease-like domain^[11].
O-6-methylguanine-DNA methyltransferase's has part is recorded as Methylated-DNA-[protein]-cysteine S-methyltransferase, active site^[12].
O-6-methylguanine-DNA methyltransferase's has part is recorded as Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding^[13].
O-6-methylguanine-DNA methyltransferase's RefSeq protein ID is recorded as NP_032624^[14].
O-6-methylguanine-DNA methyltransferase's RefSeq protein ID is recorded as XP_006507468^[15].
O-6-methylguanine-DNA methyltransferase's RefSeq protein ID is recorded as XP_006507469^[16].
O-6-methylguanine-DNA methyltransferase's RefSeq protein ID is recorded as XP_006507470^[17].
O-6-methylguanine-DNA methyltransferase's RefSeq protein ID is recorded as XP_006507471^[18].
O-6-methylguanine-DNA methyltransferase's RefSeq protein ID is recorded as XP_006507472^[19].
O-6-methylguanine-DNA methyltransferase's RefSeq protein ID is recorded as NP_001363966^[20].
O-6-methylguanine-DNA methyltransferase's RefSeq protein ID is recorded as XP_036008634^[21].
O-6-methylguanine-DNA methyltransferase's molecular function is recorded as methyltransferase activity^[22].
O-6-methylguanine-DNA methyltransferase's molecular function is recorded as transferase activity^[23].
O-6-methylguanine-DNA methyltransferase's molecular function is recorded as DNA binding^[24].
O-6-methylguanine-DNA methyltransferase's molecular function is recorded as metal ion binding^[25].
O-6-methylguanine-DNA methyltransferase's molecular function is recorded as catalytic activity^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Methylated DNA-protein cysteine methyltransferase domain superfamily, Winged helix-like DNA-binding domain superfamily, Methylated DNA-protein cysteine methyltransferase, DNA binding domain, Methylguanine DNA methyltransferase, ribonuclease-like domain, protein family, Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding domain, protein family, Methylated-DNA-[protein]-cysteine S-methyltransferase, active site, protein family

Properties

Biological process response to organic cyclic compound, cellular response to organic cyclic compound, regulation of cysteine-type endopeptidase activity involved in apoptotic process, mammary gland epithelial cell differentiation, cellular response to DNA damage stimulus, methylation, cellular response to ionizing radiation, cellular response to oxidative stress, response to folic acid, response to ethanol, response to toxic substance, DNA repair, positive regulation of double-strand break repair, negative regulation of apoptotic process, DNA dealkylation involved in DNA repair, positive regulation of DNA repair, negative regulation of cell death, DNA repair

Cell component nucleoplasm, nucleus, nucleoplasm

Encoded by Mgmt

Found in taxon house mouse

Has part(s) Methylguanine DNA methyltransferase, ribonuclease-like domain, Methylated-DNA-[protein]-cysteine S-methyltransferase, active site, Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding

Imported from wholeness_audit_2026-05-02

Molecular function methyltransferase activity, transferase activity, DNA binding, metal ion binding, catalytic activity, methylated-DNA-[protein]-cysteine S-methyltransferase activity, calcium ion binding, methylated-DNA-[protein]-cysteine S-methyltransferase activity

External References (3)

Ensembl protein id ENSMUSP00000080224

Refseq protein id NP_032624, XP_006507468, XP_006507469, XP_006507470, XP_006507471, XP_006507472, NP_001363966, XP_036008634

Uniprot protein id P26187

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ O-6-methylguanine-DNA methyltransferase — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ O-6-methylguanine-DNA methyltransferase — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ O-6-methylguanine-DNA methyltransferase — UniProt protein ID (P352): P26187. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ O-6-methylguanine-DNA methyltransferase — part of (P361): Methylated DNA-protein cysteine methyltransferase domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ O-6-methylguanine-DNA methyltransferase — part of (P361): Winged helix-like DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ O-6-methylguanine-DNA methyltransferase — part of (P361): Methylated DNA-protein cysteine methyltransferase, DNA binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ O-6-methylguanine-DNA methyltransferase — part of (P361): Methylguanine DNA methyltransferase, ribonuclease-like domain, protein family. wikidata.org.
[9] ↑ O-6-methylguanine-DNA methyltransferase — part of (P361): Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding domain, protein family. wikidata.org.
[10] ↑ O-6-methylguanine-DNA methyltransferase — part of (P361): Methylated-DNA-[protein]-cysteine S-methyltransferase, active site, protein family. wikidata.org.
[11] ↑ O-6-methylguanine-DNA methyltransferase — has part(s) (P527): Methylguanine DNA methyltransferase, ribonuclease-like domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ O-6-methylguanine-DNA methyltransferase — has part(s) (P527): Methylated-DNA-[protein]-cysteine S-methyltransferase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ O-6-methylguanine-DNA methyltransferase — has part(s) (P527): Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ O-6-methylguanine-DNA methyltransferase — RefSeq protein ID (P637): NP_032624. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ O-6-methylguanine-DNA methyltransferase — RefSeq protein ID (P637): XP_006507468. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ O-6-methylguanine-DNA methyltransferase — RefSeq protein ID (P637): XP_006507469. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ O-6-methylguanine-DNA methyltransferase — RefSeq protein ID (P637): XP_006507470. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ O-6-methylguanine-DNA methyltransferase — RefSeq protein ID (P637): XP_006507471. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ O-6-methylguanine-DNA methyltransferase — RefSeq protein ID (P637): XP_006507472. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ O-6-methylguanine-DNA methyltransferase — RefSeq protein ID (P637): NP_001363966. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ O-6-methylguanine-DNA methyltransferase — RefSeq protein ID (P637): XP_036008634. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ O-6-methylguanine-DNA methyltransferase — molecular function (P680): methyltransferase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ O-6-methylguanine-DNA methyltransferase — molecular function (P680): transferase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ O-6-methylguanine-DNA methyltransferase — molecular function (P680): DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ O-6-methylguanine-DNA methyltransferase — molecular function (P680): metal ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ O-6-methylguanine-DNA methyltransferase — molecular function (P680): catalytic activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ O-6-methylguanine-DNA methyltransferase is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). O-6-methylguanine-DNA methyltransferase. Retrieved May 3, 2026, from https://4ort.xyz/entity/o-6-methylguanine-dna-methyltransferase-q21985779

MLA

“O-6-methylguanine-DNA methyltransferase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/o-6-methylguanine-dna-methyltransferase-q21985779.

BibTeX

@misc{4ortxyz_o-6-methylguanine-dna-methyltransferase-q21985779_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{O-6-methylguanine-DNA methyltransferase}}, year = {2026}, url = {https://4ort.xyz/entity/o-6-methylguanine-dna-methyltransferase-q21985779}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): O-6-methylguanine-DNA methyltransferase — https://4ort.xyz/entity/o-6-methylguanine-dna-methyltransferase-q21985779 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/o-6-methylguanine-dna-methyltransferase-q21985779 · Last refreshed: May 3, 2026