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nicardipine

chemical compound
Class type of: dihydropyridine Q729213

Facts

14 properties
Instance of
type of chemical entity
Subclass of
dihydropyridine
Has use
medication
Active ingredient in
Cardene
Canonical SMILES
CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC
Chemical formula
C₂₆H₂₉N₃O₆
Defined daily dose
+90, +90
Mass
+479.205636
Medical condition treated
arterial hypertension, angina pectoris
Physically interacts with
Adenosine A3 receptor
Significant drug interaction
droperidol, droperidol, droperidol, droperidol, droperidol, ketoconazole, ketoconazole, ketoconazole, ketoconazole, ketoconazole
Stylized name
niCARdipine
Subject has role
calcium channel blocker, antihypertensive drug, vasodilator agent
World Health Organisation international non-proprietary name
nicardipine
🏷️ Also known as
en nicardipine en LOX725 en (R,S)-nicardipine ar نيكارديبين el Νικαρδιπίνη es Nicardipina fa نیکاردیپین id Nikardipin ja ニカルジピン ko 니카르디핀 pl nikardypina ro Nicardipină uk Нікардипін zh 尼卡地平
🔖 Identifiers · 34
OpenAlex ID
C2778043224
ATC code
C08CA04
CAS Registry Number
55985-32-5
ChEBI ID
7550, 180905
ChEMBL ID
CHEMBL1484
ChemSpider ID
4319
DSSTOX compound identifier
DTXCID903363
DSSTox substance ID
DTXSID6023363
DeCS ID
23509
DrugBank ID
DB00622
DrugCentral ID
1909
EC number
259-932-3
Show all 34 identifiers +22
ECHA Substance Infocard ID
100.054.466
Freebase ID
/m/0cx5vf
Guide to Pharmacology Ligand ID
2559
Human Metabolome Database ID
HMDB0014760
InChI
InChI=1S/C26H29N3O6/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19/h5-12,15,24,27H,13-14,16H2,1-4H3
InChIKey
ZBBHBTPTTSWHBA-UHFFFAOYSA-N
KEGG ID
C07264, D08270
MassBank accession ID
MSBNK-Waters-WA002563, MSBNK-Waters-WA002564, MSBNK-Waters-WA002565, MSBNK-Waters-WA002566, MSBNK-Waters-WA002567, MSBNK-Waters-WA002568, MSBNK-Waters-WA002569
MeSH descriptor ID
D009529
MeSH tree code
D03.383.725.203.510
MedlinePlus drug identifier
a695032
Microsoft Academic ID (discontinued)
2778043224
NDF-RT ID
N0000147944
Probes And Drugs ID
PD009884
PubChem CID
4474
RxNorm CUI
7396
SureChEMBL ID
34277
UMLS CUI
C0028005
UNII
CZ5312222S
UniChem compound ID
28894
WikiProjectMed ID
Nicardipine
World Health Organisation international non-proprietary name numeric ID
4745

Report an error or request removal Lineage (PROV-JSON)

🔗 Connections
Significant drug interaction 10
ketoconazole, ketoconazole, ketoconazole, ketoconazole, ketoconazole, droperidol, droperidol, droperidol +2 more
← Significant drug interaction 10
ketoconazole, ketoconazole, ketoconazole, ketoconazole, ketoconazole, droperidol, droperidol, droperidol +2 more
Subject has role 3
antihypertensive drug, calcium channel blocker, vasodilator agent
Medical condition treated 2
arterial hypertension, angina pectoris
← Drug or therapy used for treatment 2
arterial hypertension, angina pectoris
Has use 1
medication
← FactGrid item ID 1
Pristromi
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Summary

nicardipine is a type of chemical entity[1]. nicardipine is a type of dihydropyridine[2].

Key Facts

  • Physically interacts with: Adenosine A3 receptor[3]
  • Canonical SMILES: CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)N+[O-])C(=O)OCN+[O-])C(=O)OC">[4]
  • Chemical formula: C₂₆H₂₉N₃O₆[5]
  • Has use: medication[6]
  • Significant drug interaction: droperidol[7], ketoconazole[8]
  • Mass: 479.205636 dalton[9]
  • Medical condition treated: arterial hypertension[10], angina pectoris[11]
  • World Health Organisation international non-proprietary name: nicardipine[12]
  • Subject has role: calcium channel blocker[13], antihypertensive drug[14], vasodilator agent[15]
  • Active ingredient in: Cardene[16]
  • Defined daily dose: 90 milligram[17]
  • Stylized name: niCARdipine[18]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  2. [4] ↑ . PubChem. Retrieved . wikidata.org.
  3. [5] ↑ . PubChem. Retrieved . wikidata.org.
  4. [2] ↑ . NDF-RT. Retrieved . wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  7. [8] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  8. [9] ↑ . PubChem. Retrieved . wikidata.org.
  9. [10] ↑ . NDF-RT. Retrieved . wikidata.org.
  10. [11] ↑ . NDF-RT. Retrieved . wikidata.org.
  11. [12] ↑ . ChEMBL. Retrieved . wikidata.org.
  12. [13] ↑ . NDF-RT. Retrieved . wikidata.org.
  13. [14] ↑ . Medical Subject Headings. Retrieved . wikidata.org.
  14. [15] ↑ . Medical Subject Headings. Retrieved . wikidata.org.
  15. [16] ↑ . RxNorm. Retrieved . wikidata.org.
  16. [17] ↑ . whocc.no. whocc.no. Provenance: wikidata.org.
  17. [18] ↑ . fda.gov. Retrieved . fda.gov. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). nicardipine. Retrieved November 6, 2026, from https://4ort.xyz/entity/nicardipine
MLA “nicardipine.” 4ort.xyz Knowledge Graph, 4ort.xyz, 6 Nov. 2026, https://4ort.xyz/entity/nicardipine.
BibTeX @misc{4ortxyz_nicardipine_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{nicardipine}}, year = {2026}, url = {https://4ort.xyz/entity/nicardipine}, note = {Accessed: 2026-11-06}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): nicardipine — https://4ort.xyz/entity/nicardipine (retrieved 2026-11-06)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 20w ago · Nabbegat · 2026-06-19 view diff on Wikidata ↗
    Defined daily dose → {'unit': 'Q3241121', 'amount': '+90'}, {'unit': 'Q3241121', 'amount': '+90'}
    Instance of → type of chemical entity
    Has use → medication
    Medical condition treated → arterial hypertension, angina pectoris
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||tr */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/37300|batch #37300]]"
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