Neuralized E3 ubiquitin protein ligase 1A

mammalian protein found in Mus musculus

Protein protein Q21496302

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Summary

Neuralized E3 ubiquitin protein ligase 1A is a protein^[1].

Key Facts

Part of: Neuralized^[2], Zinc finger, RING/FYVE/PHD-type^[3], membrane protein^[4], Neuralized homology repeat (NHR) domain, protein family^[5], Zinc finger, RING-type, protein family^[6]
Has part(s): Zinc finger, RING-type^[7], Neuralized homology repeat (NHR) domain^[8]
Molecular function: translation factor activity, non-nucleic acid binding^[9], ubiquitin protein ligase activity^[10], metal ion binding^[11], ubiquitin-protein transferase activity^[12], protein binding^[13], transferase activity^[14], ubiquitin protein ligase activity^[15]
Cell component: cytoplasm^[16], perikaryon^[17], postsynaptic membrane^[18], cell projection^[19], membrane^[20], postsynaptic density^[21], plasma membrane^[22]

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of Neuralized, Zinc finger, RING/FYVE/PHD-type, membrane protein, Neuralized homology repeat (NHR) domain, protein family, Zinc finger, RING-type, protein family

Properties

Biological process Notch signaling pathway, flagellated sperm motility, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of dendritic spine development, protein monoubiquitination, sperm axoneme assembly, positive regulation of synapse maturation, brain development, positive regulation of long-term neuronal synaptic plasticity, protein ubiquitination, positive regulation of apoptotic process, cellular response to amino acid stimulus, lactation, skeletal muscle tissue development, positive regulation of filopodium assembly, regulation of translation, negative regulation of cell population proliferation, negative regulation of Notch signaling pathway, nervous system development, negative regulation of Notch signaling pathway

Cell component cytoplasm, perikaryon, postsynaptic membrane, cell projection, membrane, postsynaptic density, plasma membrane, dendritic spine, synapse, cell junction, dendrite, perinuclear region of cytoplasm, nucleus, apical dendrite, plasma membrane, postsynaptic density

Encoded by Neurl1a

Found in taxon house mouse

Has part(s) Zinc finger, RING-type, Neuralized homology repeat (NHR) domain

Imported from wholeness_audit_2026-05-02

Molecular function translation factor activity, non-nucleic acid binding, ubiquitin protein ligase activity, metal ion binding, ubiquitin-protein transferase activity, protein binding, transferase activity, ubiquitin protein ligase activity

Identifiers (3)

Ensembl protein id ENSMUSP00000107438, ENSMUSP00000107439

Refseq protein id NP_001156952, NP_067335

Uniprot protein id Q923S6

🏷️ Also known as

en E3 ubiquitin-protein ligase NEURL1 en m-neu1 en m-neuralized 1 en neuralized1 en Neuralized E3 ubiquitin protein ligase 1A en neuralized homolog 1A en neuralized-like homolog en neuralized-like protein 1 en neuralized-like protein 1A en Neurl1a en RING-type E3 ubiquitin transferase NEURL1

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Neuralized E3 ubiquitin protein ligase 1A — part of (P361): Neuralized. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[3] ↑ Neuralized E3 ubiquitin protein ligase 1A — part of (P361): Zinc finger, RING/FYVE/PHD-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[4] ↑ Neuralized E3 ubiquitin protein ligase 1A — part of (P361): membrane protein. wikidata.org.
[5] ↑ Neuralized E3 ubiquitin protein ligase 1A — part of (P361): Neuralized homology repeat (NHR) domain, protein family. wikidata.org.
[6] ↑ Neuralized E3 ubiquitin protein ligase 1A — part of (P361): Zinc finger, RING-type, protein family. wikidata.org.
[7] ↑ Neuralized E3 ubiquitin protein ligase 1A — has part(s) (P527): Zinc finger, RING-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Neuralized E3 ubiquitin protein ligase 1A — has part(s) (P527): Neuralized homology repeat (NHR) domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Neuralized E3 ubiquitin protein ligase 1A — molecular function (P680): translation factor activity, non-nucleic acid binding. Neuralized1 Activates CPEB3: A Function for Nonproteolytic Ubiquitin in Synaptic Plasticity and Memory Storage. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Neuralized E3 ubiquitin protein ligase 1A — molecular function (P680): ubiquitin protein ligase activity. Neuralized1 Activates CPEB3: A Function for Nonproteolytic Ubiquitin in Synaptic Plasticity and Memory Storage. Retrieved 2018-10-11. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Neuralized E3 ubiquitin protein ligase 1A — molecular function (P680): metal ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Neuralized E3 ubiquitin protein ligase 1A — molecular function (P680): ubiquitin-protein transferase activity. Neuralized1 Activates CPEB3: A Function for Nonproteolytic Ubiquitin in Synaptic Plasticity and Memory Storage. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Neuralized E3 ubiquitin protein ligase 1A — molecular function (P680): protein binding. Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Neuralized E3 ubiquitin protein ligase 1A — molecular function (P680): transferase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Neuralized E3 ubiquitin protein ligase 1A — molecular function (P680): ubiquitin protein ligase activity. Neuralized1 Activates CPEB3: A Function for Nonproteolytic Ubiquitin in Synaptic Plasticity and Memory Storage. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Neuralized E3 ubiquitin protein ligase 1A — cell component (P681): cytoplasm. Isolation of a murine homologue of the Drosophila neuralized gene, a gene required for axonemal integrity in spermatozoa and terminal maturation of the mammary gland. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Neuralized E3 ubiquitin protein ligase 1A — cell component (P681): perikaryon. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Neuralized E3 ubiquitin protein ligase 1A — cell component (P681): postsynaptic membrane. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Neuralized E3 ubiquitin protein ligase 1A — cell component (P681): cell projection. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Neuralized E3 ubiquitin protein ligase 1A — cell component (P681): membrane. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Neuralized E3 ubiquitin protein ligase 1A — cell component (P681): postsynaptic density. GOA. Retrieved 2018-10-11. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Neuralized E3 ubiquitin protein ligase 1A — cell component (P681): plasma membrane. GOA. Retrieved 2018-10-11. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Neuralized E3 ubiquitin protein ligase 1A is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Neuralized E3 ubiquitin protein ligase 1A. Retrieved May 3, 2026, from https://4ort.xyz/entity/neuralized-e3-ubiquitin-protein-ligase-1a

MLA

“Neuralized E3 ubiquitin protein ligase 1A.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/neuralized-e3-ubiquitin-protein-ligase-1a.

BibTeX

@misc{4ortxyz_neuralized-e3-ubiquitin-protein-ligase-1a_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Neuralized E3 ubiquitin protein ligase 1A}}, year = {2026}, url = {https://4ort.xyz/entity/neuralized-e3-ubiquitin-protein-ligase-1a}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Neuralized E3 ubiquitin protein ligase 1A — https://4ort.xyz/entity/neuralized-e3-ubiquitin-protein-ligase-1a (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/neuralized-e3-ubiquitin-protein-ligase-1a · Last refreshed: May 3, 2026