Neural precursor cell expressed, developmentally down-regulated gene 4-like

mammalian protein found in Mus musculus

Protein protein Q21985871

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Neural precursor cell expressed, developmentally down-regulated gene 4-like

Summary

Neural precursor cell expressed, developmentally down-regulated gene 4-like is a protein^[1].

Key Facts

Neural precursor cell expressed, developmentally down-regulated gene 4-like's instance of is recorded as protein^[2].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's UniProt protein ID is recorded as Q8CFI0^[3].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's part of is recorded as HECT, E3 ligase catalytic domain^[4].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's part of is recorded as WW domain superfamily^[5].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's part of is recorded as C2 domain superfamily^[6].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's part of is recorded as E3 ubiquitin-protein ligase, SMURF1 type^[7].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's part of is recorded as auxiliary protein involved in transmembrane transport^[8].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's part of is recorded as HECT domain, protein family^[9].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's part of is recorded as C2 domain, protein family^[10].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's part of is recorded as WW domain, protein family^[11].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's has part is recorded as HECT domain^[12].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's has part is recorded as WW domain^[13].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's has part is recorded as C2 domain^[14].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as NP_001107858^[15].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as NP_114087^[16].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as XP_006526433^[17].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as XP_006526434^[18].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as XP_006526436^[19].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as XP_011245346^[20].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as XP_011245349^[21].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as XP_017173504^[22].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as XP_017173505^[23].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as XP_030106497^[24].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as XP_030106501^[25].
Neural precursor cell expressed, developmentally down-regulated gene 4-like's RefSeq protein ID is recorded as XP_030106502^[26].

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Quick Facts

Instance of protein

Part of HECT, E3 ligase catalytic domain, WW domain superfamily, C2 domain superfamily, E3 ubiquitin-protein ligase, SMURF1 type, auxiliary protein involved in transmembrane transport, HECT domain, protein family, C2 domain, protein family, WW domain, protein family

Properties

Biological process positive regulation of cation channel activity, cell differentiation, negative regulation of sodium ion transmembrane transport, response to salt stress, regulation of bicellular tight junction assembly, negative regulation of sodium ion transmembrane transporter activity, regulation of membrane potential, regulation of ion transmembrane transport, response to metal ion, regulation of membrane depolarization, protein K48-linked ubiquitination, negative regulation of protein localization to cell surface, negative regulation of potassium ion transmembrane transporter activity, regulation of potassium ion transmembrane transporter activity, positive regulation of sodium ion transport, negative regulation of potassium ion transmembrane transport, regulation of membrane repolarization, positive regulation of dendrite extension, negative regulation of systemic arterial blood pressure, proteasome-mediated ubiquitin-dependent protein catabolic process, negative regulation of sodium ion transport, ubiquitin-dependent protein catabolic process, protein ubiquitination, protein monoubiquitination, regulation of protein stability, positive regulation of protein catabolic process, ventricular cardiac muscle cell action potential, positive regulation of caveolin-mediated endocytosis, protein polyubiquitination, ubiquitin-dependent protein catabolic process, protein ubiquitination, proteasome-mediated ubiquitin-dependent protein catabolic process, positive regulation of protein catabolic process, regulation of dendrite morphogenesis, negative regulation of potassium ion transmembrane transport, negative regulation of sodium ion transmembrane transporter activity

Cell component plasma membrane, endosome, multivesicular body, Golgi apparatus, cytoplasm

Encoded by Nedd4l

Found in taxon house mouse

Has part(s) HECT domain, WW domain, C2 domain

Imported from wholeness_audit_2026-05-02

Molecular function potassium channel inhibitor activity, sodium channel regulator activity, transmembrane transporter binding, potassium channel regulator activity, protein binding, ubiquitin-protein transferase activity, sodium channel inhibitor activity, transferase activity, ubiquitin protein ligase activity, ubiquitin protein ligase activity

External References (5)

Ensembl protein id ENSMUSP00000158050, ENSMUSP00000157490, ENSMUSP00000158140, ENSMUSP00000157929, ENSMUSP00000157910, ENSMUSP00000153107, ENSMUSP00000158026, ENSMUSP00000158238, ENSMUSP00000158272, ENSMUSP00000132838, ENSMUSP00000158043, ENSMUSP00000157658, ENSMUSP00000153526, ENSMUSP00000153052, ENSMUSP00000153594, ENSMUSP00000158323, ENSMUSP00000158044, ENSMUSP00000157586, ENSMUSP00000079280, ENSMUSP00000158688

Pdb structure id 1WR3, 1WR4, 1WR7

Refseq protein id NP_001107858, NP_114087, XP_006526433, XP_006526434, XP_006526436, XP_011245346, XP_011245349, XP_017173504, XP_017173505, XP_030106497, XP_030106501, XP_030106502, XP_030106503, XP_030106504, XP_036017204, XP_036017205, XP_036017206, XP_036017207, XP_036017208, XP_036017209, XP_036017210, XP_036017211, XP_036017212, XP_036017213, XP_036017214, XP_036017215, XP_036017216, XP_036017217, XP_036017218, XP_036017219, XP_036017220, XP_036017221, XP_036017222, XP_036017223, XP_036017224, XP_036017225, XP_036017226, XP_036017227, XP_036017228, XP_036017229, XP_036017230, NP_001390936, NP_001390937, NP_001390938, NP_001390942

Transporter classification database id 8.A.30.1.1

Uniprot protein id Q8CFI0

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — instance of (P31): protein. Q905695. Retrieved 2021-11-17. wikidata.org.
[3] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — UniProt protein ID (P352): Q8CFI0. Q905695. Retrieved 2021-11-17. wikidata.org.
[4] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — part of (P361): HECT, E3 ligase catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — part of (P361): WW domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — part of (P361): C2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — part of (P361): E3 ubiquitin-protein ligase, SMURF1 type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — part of (P361): auxiliary protein involved in transmembrane transport. Retrieved 2019-10-02. wikidata.org.
[9] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — part of (P361): HECT domain, protein family. wikidata.org.
[10] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — part of (P361): C2 domain, protein family. wikidata.org.
[11] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — part of (P361): WW domain, protein family. wikidata.org.
[12] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — has part(s) (P527): HECT domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — has part(s) (P527): WW domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — has part(s) (P527): C2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): NP_001107858. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): NP_114087. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): XP_006526433. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): XP_006526434. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): XP_006526436. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): XP_011245346. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): XP_011245349. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): XP_017173504. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): XP_017173505. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): XP_030106497. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): XP_030106501. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like — RefSeq protein ID (P637): XP_030106502. Q20641742. Retrieved 2022-03-20. wikidata.org.

Class ancestry

[1] ↑ Neural precursor cell expressed, developmentally down-regulated gene 4-like is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Neural precursor cell expressed, developmentally down-regulated gene 4-like. Retrieved May 3, 2026, from https://4ort.xyz/entity/neural-precursor-cell-expressed-developmentally-down-regulated-gene-4-like

MLA

“Neural precursor cell expressed, developmentally down-regulated gene 4-like.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/neural-precursor-cell-expressed-developmentally-down-regulated-gene-4-like.

BibTeX

@misc{4ortxyz_neural-precursor-cell-expressed-developmentally-down-regulated-gene-4-like_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Neural precursor cell expressed, developmentally down-regulated gene 4-like}}, year = {2026}, url = {https://4ort.xyz/entity/neural-precursor-cell-expressed-developmentally-down-regulated-gene-4-like}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Neural precursor cell expressed, developmentally down-regulated gene 4-like — https://4ort.xyz/entity/neural-precursor-cell-expressed-developmentally-down-regulated-gene-4-like (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/neural-precursor-cell-expressed-developmentally-down-regulated-gene-4-like · Last refreshed: May 3, 2026