N-ribosyldihydronicotinamide:quinone reductase 2

mammalian protein found in Homo sapiens

Protein protein Q21120139

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N-ribosyldihydronicotinamide:quinone reductase 2

Summary

N-ribosyldihydronicotinamide:quinone reductase 2 is a protein^[1].

Key Facts

N-ribosyldihydronicotinamide:quinone reductase 2's instance of is recorded as protein^[2].
N-ribosyldihydronicotinamide:quinone reductase 2 is part of Flavoprotein-like superfamily^[3].
N-ribosyldihydronicotinamide:quinone reductase 2 is part of Flavodoxin-like fold, protein family^[4].
N-ribosyldihydronicotinamide:quinone reductase 2 comprises Flavodoxin-like fold^[5].
N-ribosyldihydronicotinamide:quinone reductase 2's molecular function is recorded as protein binding^[6].
N-ribosyldihydronicotinamide:quinone reductase 2's molecular function is recorded as metal ion binding^[7].
N-ribosyldihydronicotinamide:quinone reductase 2's molecular function is recorded as dihydronicotinamide riboside quinone reductase activity^[8].
N-ribosyldihydronicotinamide:quinone reductase 2's molecular function is recorded as zinc ion binding^[9].
N-ribosyldihydronicotinamide:quinone reductase 2's molecular function is recorded as electron transfer activity^[10].
N-ribosyldihydronicotinamide:quinone reductase 2's molecular function is recorded as oxidoreductase activity^[11].
N-ribosyldihydronicotinamide:quinone reductase 2's molecular function is recorded as oxidoreductase activity, acting on other nitrogenous compounds as donors^[12].

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Quick Facts

Instance of protein

Part of Flavoprotein-like superfamily, Flavodoxin-like fold, protein family

Properties

Biological process memory, positive regulation of neuron apoptotic process, positive regulation of vascular associated smooth muscle cell proliferation, positive regulation of ERK1 and ERK2 cascade, positive regulation of reactive oxygen species metabolic process, xenobiotic metabolic process, electron transport chain

Cell component extracellular exosome, nucleoplasm, cytoplasm, cytosol, cytosol, extracellular exosome

Ec enzyme number 1.10.5.1

Encoded by NQO2

Found in taxon Homo sapiens

Has part(s) Flavodoxin-like fold

Molecular function protein binding, metal ion binding, dihydronicotinamide riboside quinone reductase activity, zinc ion binding, electron transfer activity, oxidoreductase activity, oxidoreductase activity, acting on other nitrogenous compounds as donors, chloride ion binding, protein homodimerization activity, FAD binding, melatonin binding, resveratrol binding, NAD(P)H dehydrogenase (quinone) activity, electron transfer activity, oxidoreductase activity, dihydronicotinamide riboside quinone reductase activity

External References (4)

Ensembl protein id ENSP00000337773, ENSP00000369795, ENSP00000369822, ENSP00000369806, ENSP00000369821, ENSP00000369839, ENSP00000380829, ENSP00000406951, ENSP00000475864

Pdb structure id 1QR2, 1SG0, 1XI2, 1ZX1, 2BZS, 2QMY, 2QMZ, 2QR2, 2QWX, 2QX4, 2QX6, 2QX8, 2QX9, 3FW1, 3G5M, 3GAM, 3NFR, 3NHF, 3NHJ, 3NHK, 3NHL, 3NHP, 3NHR, 3NHS, 3NHU, 3NHW, 3NHY, 3O2N, 3O73, 3OVM, 3OWH, 3OWX, 3OX1, 3OX2, 3OX3, 3TE7, 3TEM, 3TZB, 3UXE, 3UXH, 4FGJ, 4FGK, 4FGL, 4GQI, 4GR9, 4QOD, 4QOE, 4QOF, 4QOG, 4QOH, 4QOI, 4QOJ, 4U7F, 4U7G, 4U7H, 4XDG, 4XDH, 4ZVL, 4ZVM, 4ZVK, 5LBT, 5LBU, 5BUC, 4ZVN

Refseq protein id NP_000895, NP_001277150, NP_001277151, NP_001305869

Uniprot protein id P16083

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — part of (P361): Flavoprotein-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[4] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — part of (P361): Flavodoxin-like fold, protein family. wikidata.org.
[5] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — has part(s) (P527): Flavodoxin-like fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — molecular function (P680): protein binding. A proteome-scale map of the human interactome network. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — molecular function (P680): metal ion binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — molecular function (P680): dihydronicotinamide riboside quinone reductase activity. GOA. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — molecular function (P680): zinc ion binding. Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — molecular function (P680): electron transfer activity. Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2. Retrieved 2017-10-31. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — molecular function (P680): oxidoreductase activity. GOA. Retrieved 2017-10-31. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 — molecular function (P680): oxidoreductase activity, acting on other nitrogenous compounds as donors. Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ N-ribosyldihydronicotinamide:quinone reductase 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). N-ribosyldihydronicotinamide:quinone reductase 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/n-ribosyldihydronicotinamide-quinone-reductase-2

MLA

“N-ribosyldihydronicotinamide:quinone reductase 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/n-ribosyldihydronicotinamide-quinone-reductase-2.

BibTeX

@misc{4ortxyz_n-ribosyldihydronicotinamide-quinone-reductase-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{N-ribosyldihydronicotinamide:quinone reductase 2}}, year = {2026}, url = {https://4ort.xyz/entity/n-ribosyldihydronicotinamide-quinone-reductase-2}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): N-ribosyldihydronicotinamide:quinone reductase 2 — https://4ort.xyz/entity/n-ribosyldihydronicotinamide-quinone-reductase-2 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/n-ribosyldihydronicotinamide-quinone-reductase-2 · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

4w ago · Boghog · 2026-07-24 view diff on Wikidata ↗

Imported from → —

Encoded by → NQO2

Wikidata description → mammalian protein found in Homo sapiens

Molecular function → protein binding, metal ion binding, dihydronicotinamide riboside quinone reductase activity +13

+ 11 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ [[Property:P591]]: 1.10.5.1, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"

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