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MLH1

protein-coding gene in the species Homo sapiens
Class type of: protein-coding gene Q14911708

Facts

11 properties
Instance of
gene
Subclass of
protein-coding gene[2]
Chromosome
human chromosome 3[11]
Cytogenetic location
3p22.2[18]
Encodes
MutL homolog 1, DNA mismatch repair protein Mlh1[8][9]
Found in taxon
Homo sapiens[10]
Genetic association
mismatch repair cancer syndrome, Muir-Torre syndrome, colorectal cancer, large intestine cancer, colon carcinoma, Lynch syndrome[12][13][14][15][16][17]
Genomic end
37050846[5]
Genomic start
36993466[4]
HomoloGene ID
208[3]
Ortholog
Mlh1, MLH1, Mlh1, Mlh1, mlh1, mlh-1[6][7]
🏷️ Also known as
en COCA2 en FCC2 en hMLH1 en HNPCC en HNPCC2 en MLH1 en mutL homolog 1
🔖 Identifiers · 12
OpenAlex ID
C111425858
CIViC gene ID
3532
Ensembl gene ID
ENSG00000076242
Entrez Gene ID
4292
Exact match
identifiers.org
Freebase ID
/m/02pvqn9
HGNC ID
7127
HGNC gene symbol
MLH1
Microsoft Academic ID (discontinued)
111425858
OMIM ID
120436
RefSeq RNA ID
XM_011533727, NM_000249, NM_001167617, NM_001167618, NM_001167619, NM_001258271, NM_001258273, NM_001258274, XM_005265161, XM_005265163, XM_005265164, XM_005265166, XM_017006449, XM_017006450, XM_017006451
UMLS CUI
C0879389

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🔗 Connections
Genetic association 4
colorectal cancer, Lynch syndrome, Muir-Torre syndrome, mismatch repair cancer syndrome
← Genetic association 4
colorectal cancer, Lynch syndrome, Muir-Torre syndrome, mismatch repair cancer syndrome
Chromosome 1
human chromosome 3
Found in taxon 1
Homo sapiens
Instance of 1
gene
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Summary

MLH1 is a gene[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . Ensembl Release 87. wikidata.org.
  2. [3] ↑ . NCBI Gene. Retrieved . wikidata.org.
  3. [4] ↑ . ncbi.nlm.nih.gov. ncbi.nlm.nih.gov. Provenance: wikidata.org.
  4. [5] ↑ . ncbi.nlm.nih.gov. ncbi.nlm.nih.gov. Provenance: wikidata.org.
  5. [6] ↑ . HomoloGene build68. omabrowser.org. Provenance: wikidata.org.
  6. [7] ↑ . Orthologous MAtrix. omabrowser.org. Provenance: wikidata.org.
  7. [8] ↑ . UniProt. Retrieved . wikidata.org.
  8. [9] ↑ . UniProt. Retrieved . wikidata.org.
  9. [10] ↑ . wikidata.org.
  10. [11] ↑ . ncbi.nlm.nih.gov. ncbi.nlm.nih.gov. Provenance: wikidata.org.
  11. [12] ↑ . UniProt. Retrieved . search.clinicalgenome.org. Provenance: wikidata.org.
  12. [13] ↑ . UniProt. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  13. [14] ↑ . UniProt. Retrieved . wikidata.org.
  14. [15] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  15. [16] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  16. [17] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  17. [18] ↑ . NCBI Gene. ncbi.nlm.nih.gov. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). MLH1. Retrieved November 9, 2026, from https://4ort.xyz/entity/mlh1
MLA “MLH1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 9 Nov. 2026, https://4ort.xyz/entity/mlh1.
BibTeX @misc{4ortxyz_mlh1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{MLH1}}, year = {2026}, url = {https://4ort.xyz/entity/mlh1}, note = {Accessed: 2026-11-09}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): MLH1 — https://4ort.xyz/entity/mlh1 (retrieved 2026-11-09)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 25w ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    Genetic association → mismatch repair cancer syndrome, Muir-Torre syndrome, colorectal cancer +1
    Chromosome → human chromosome 3
    Instance of → gene
    Ortholog → Mlh1, MLH1, Wikidata item
    + 3 other properties edited (see Wikidata diff for full list)
    "Changed [gsw] labels, descriptions or aliases: QuickStatements 3.0 batch #32527: human gene name and description in Alemannic"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.