Mixed lineage kinase domain-like

mammalian protein found in Mus musculus

Protein protein Q21494743

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Summary

Mixed lineage kinase domain-like is a protein^[1].

Key Facts

Mixed lineage kinase domain-like's instance of is recorded as protein^[2].
Mixed lineage kinase domain-like's UniProt protein ID is recorded as Q9D2Y4^[3].
Mixed lineage kinase domain-like's part of is recorded as Protein kinase-like domain superfamily^[4].
Mixed lineage kinase domain-like's part of is recorded as Adaptor protein Cbl, N-terminal domain superfamily^[5].
Mixed lineage kinase domain-like's part of is recorded as membrane protein^[6].
Mixed lineage kinase domain-like's part of is recorded as Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family^[7].
Mixed lineage kinase domain-like's part of is recorded as Protein kinase domain, protein family^[8].
Mixed lineage kinase domain-like's has part is recorded as serine-threonine/tyrosine-protein kinase, catalytic domain^[9].
Mixed lineage kinase domain-like's has part is recorded as protein kinase domain^[10].
Mixed lineage kinase domain-like's RefSeq protein ID is recorded as NP_001297542^[11].
Mixed lineage kinase domain-like's RefSeq protein ID is recorded as NP_083281^[12].
Mixed lineage kinase domain-like's RefSeq protein ID is recorded as XP_006531505^[13].
Mixed lineage kinase domain-like's RefSeq protein ID is recorded as XP_006531506^[14].
Mixed lineage kinase domain-like's RefSeq protein ID is recorded as XP_030099680^[15].
Mixed lineage kinase domain-like's RefSeq protein ID is recorded as XP_036010235^[16].
Mixed lineage kinase domain-like's PDB structure ID is recorded as 4BTF^[17].
Mixed lineage kinase domain-like's PDB structure ID is recorded as 4M68^[18].
Mixed lineage kinase domain-like's PDB structure ID is recorded as 4M69^[19].
Mixed lineage kinase domain-like's molecular function is recorded as nucleotide binding^[20].
Mixed lineage kinase domain-like's molecular function is recorded as protein kinase activity^[21].
Mixed lineage kinase domain-like's molecular function is recorded as ATP binding^[22].
Mixed lineage kinase domain-like's molecular function is recorded as protein kinase binding^[23].
Mixed lineage kinase domain-like's molecular function is recorded as protein binding^[24].
Mixed lineage kinase domain-like's molecular function is recorded as identical protein binding^[25].
Mixed lineage kinase domain-like's molecular function is recorded as signal transducer activity^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of Protein kinase-like domain superfamily, Adaptor protein Cbl, N-terminal domain superfamily, membrane protein, Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family, Protein kinase domain, protein family

Properties

Biological process necroptosis, programmed cell death, protein homotrimerization, protein phosphorylation, intracellular signal transduction, cell surface receptor signaling pathway, protein phosphorylation, MAPK cascade, protein phosphorylation

Cell component membrane, cytoplasm, plasma membrane, cytoplasm, plasma membrane

Encoded by Mlkl

Found in taxon house mouse

Has part(s) serine-threonine/tyrosine-protein kinase, catalytic domain, protein kinase domain

Imported from wholeness_audit_2026-05-02

Molecular function nucleotide binding, protein kinase activity, ATP binding, protein kinase binding, protein binding, identical protein binding, signal transducer activity, protein-containing complex binding, protein serine/threonine kinase activity, JUN kinase kinase kinase activity

External References (4)

Ensembl protein id ENSMUSP00000055521, ENSMUSP00000113718, ENSMUSP00000114701

Pdb structure id 4BTF, 4M68, 4M69

Refseq protein id NP_001297542, NP_083281, XP_006531505, XP_006531506, XP_030099680, XP_036010235

Uniprot protein id Q9D2Y4

🏷️ Also known as

en Mixed lineage kinase domain-like en mixed lineage kinase domain-like protein en Mlkl

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Mixed lineage kinase domain-like — instance of (P31): protein. UniProt. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Mixed lineage kinase domain-like — UniProt protein ID (P352): Q9D2Y4. UniProt. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Mixed lineage kinase domain-like — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Mixed lineage kinase domain-like — part of (P361): Adaptor protein Cbl, N-terminal domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Mixed lineage kinase domain-like — part of (P361): membrane protein. wikidata.org.
[7] ↑ Mixed lineage kinase domain-like — part of (P361): Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[8] ↑ Mixed lineage kinase domain-like — part of (P361): Protein kinase domain, protein family. wikidata.org.
[9] ↑ Mixed lineage kinase domain-like — has part(s) (P527): serine-threonine/tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Mixed lineage kinase domain-like — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Mixed lineage kinase domain-like — RefSeq protein ID (P637): NP_001297542. Q20641742. Retrieved 2022-03-20. wikidata.org.
[12] ↑ Mixed lineage kinase domain-like — RefSeq protein ID (P637): NP_083281. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ Mixed lineage kinase domain-like — RefSeq protein ID (P637): XP_006531505. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ Mixed lineage kinase domain-like — RefSeq protein ID (P637): XP_006531506. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ Mixed lineage kinase domain-like — RefSeq protein ID (P637): XP_030099680. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Mixed lineage kinase domain-like — RefSeq protein ID (P637): XP_036010235. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Mixed lineage kinase domain-like — PDB structure ID (P638): 4BTF. UniProt. Retrieved 2016-03-20. wikidata.org.
[18] ↑ Mixed lineage kinase domain-like — PDB structure ID (P638): 4M68. UniProt. Retrieved 2016-03-20. wikidata.org.
[19] ↑ Mixed lineage kinase domain-like — PDB structure ID (P638): 4M69. UniProt. Retrieved 2016-03-20. wikidata.org.
[20] ↑ Mixed lineage kinase domain-like — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Mixed lineage kinase domain-like — molecular function (P680): protein kinase activity. The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Mixed lineage kinase domain-like — molecular function (P680): ATP binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Mixed lineage kinase domain-like — molecular function (P680): protein kinase binding. Structural insights into RIP3-mediated necroptotic signaling. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Mixed lineage kinase domain-like — molecular function (P680): protein binding. Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Mixed lineage kinase domain-like — molecular function (P680): identical protein binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Mixed lineage kinase domain-like — molecular function (P680): signal transducer activity. GOA. Retrieved 2018-03-27. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Mixed lineage kinase domain-like is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Mixed lineage kinase domain-like. Retrieved May 3, 2026, from https://4ort.xyz/entity/mixed-lineage-kinase-domain-like

MLA

“Mixed lineage kinase domain-like.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/mixed-lineage-kinase-domain-like.

BibTeX

@misc{4ortxyz_mixed-lineage-kinase-domain-like_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Mixed lineage kinase domain-like}}, year = {2026}, url = {https://4ort.xyz/entity/mixed-lineage-kinase-domain-like}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Mixed lineage kinase domain-like — https://4ort.xyz/entity/mixed-lineage-kinase-domain-like (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/mixed-lineage-kinase-domain-like · Last refreshed: May 3, 2026