Methyl-CpG binding domain protein 2

mammalian protein found in Mus musculus

Protein protein Q21986534

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Summary

Methyl-CpG binding domain protein 2 is a protein^[1].

Key Facts

Methyl-CpG binding domain protein 2's instance of is recorded as protein^[2].
Methyl-CpG binding domain protein 2's subclass of is recorded as protein^[3].
Methyl-CpG binding domain protein 2's UniProt protein ID is recorded as Q9Z2E1^[4].
Methyl-CpG binding domain protein 2's part of is recorded as DNA-binding domain superfamily^[5].
Methyl-CpG binding domain protein 2's part of is recorded as Methyl-CpG-binding domain protein 2/3, p55-binding region, protein family^[6].
Methyl-CpG binding domain protein 2's part of is recorded as Methyl-CpG binding protein 2/3, C-terminal domain, protein family^[7].
Methyl-CpG binding domain protein 2's part of is recorded as Methyl-CpG DNA binding domain, protein family^[8].
Methyl-CpG binding domain protein 2's has part is recorded as Methyl-CpG-binding domain protein 2/3, p55-binding region^[9].
Methyl-CpG binding domain protein 2's has part is recorded as Methyl-CpG binding protein 2/3, C-terminal domain^[10].
Methyl-CpG binding domain protein 2's has part is recorded as methyl-CpG DNA binding^[11].
Methyl-CpG binding domain protein 2's RefSeq protein ID is recorded as NP_001298000^[12].
Methyl-CpG binding domain protein 2's RefSeq protein ID is recorded as NP_034903^[13].
Methyl-CpG binding domain protein 2's RefSeq protein ID is recorded as XP_006525774^[14].
Methyl-CpG binding domain protein 2's RefSeq protein ID is recorded as XP_036016901^[15].
Methyl-CpG binding domain protein 2's molecular function is recorded as DNA binding^[16].
Methyl-CpG binding domain protein 2's molecular function is recorded as protein domain specific binding^[17].
Methyl-CpG binding domain protein 2's molecular function is recorded as methyl-CpG binding^[18].
Methyl-CpG binding domain protein 2's molecular function is recorded as C2H2 zinc finger domain binding^[19].
Methyl-CpG binding domain protein 2's molecular function is recorded as protein binding^[20].
Methyl-CpG binding domain protein 2's molecular function is recorded as siRNA binding^[21].
Methyl-CpG binding domain protein 2's molecular function is recorded as mRNA binding^[22].
Methyl-CpG binding domain protein 2's molecular function is recorded as chromatin binding^[23].
Methyl-CpG binding domain protein 2's molecular function is recorded as methyl-CpG binding^[24].
Methyl-CpG binding domain protein 2's cell component is recorded as cytoplasm^[25].
Methyl-CpG binding domain protein 2's cell component is recorded as histone deacetylase complex^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of DNA-binding domain superfamily, Methyl-CpG-binding domain protein 2/3, p55-binding region, protein family, Methyl-CpG binding protein 2/3, C-terminal domain, protein family, Methyl-CpG DNA binding domain, protein family

Properties

Biological process regulation of transcription, DNA-templated, transcription, DNA-templated, positive regulation of Wnt signaling pathway, regulation of cell population proliferation, cellular response to organic cyclic compound, development of the heart, embryonic organ development, regulation of DNA methylation, ageing, response to estradiol, response to nutrient levels, Maternal behavior, response to organic cyclic compound, response to mechanical stimulus, DNA methylation-dependent heterochromatin assembly, negative regulation of transcription by RNA polymerase II, positive regulation of chromatin binding, negative regulation of transcription by RNA polymerase II

Cell component cytoplasm, histone deacetylase complex, heterochromatin, nucleolus, chromatin, nucleus, nucleoplasm, cytosol, nucleus

Encoded by Mbd2

Found in taxon house mouse

Has part(s) Methyl-CpG-binding domain protein 2/3, p55-binding region, Methyl-CpG binding protein 2/3, C-terminal domain, methyl-CpG DNA binding

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, protein domain specific binding, methyl-CpG binding, C2H2 zinc finger domain binding, protein binding, siRNA binding, mRNA binding, chromatin binding, methyl-CpG binding

External References (3)

Ensembl protein id ENSMUSP00000073701, ENSMUSP00000110596, ENSMUSP00000120508

Refseq protein id NP_001298000, NP_034903, XP_006525774, XP_036016901

Uniprot protein id Q9Z2E1

🏷️ Also known as

en Mbd2 en methyl-CpG-binding domain protein 2 en Methyl-CpG binding domain protein 2 en methyl-CpG-binding protein MBD2 en testis-specific methyl-CpG binding protein 2

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Methyl-CpG binding domain protein 2 — instance of (P31): protein. UniProt. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Methyl-CpG binding domain protein 2 — subclass of (P279): protein. UniProt. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Methyl-CpG binding domain protein 2 — UniProt protein ID (P352): Q9Z2E1. UniProt. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Methyl-CpG binding domain protein 2 — part of (P361): DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Methyl-CpG binding domain protein 2 — part of (P361): Methyl-CpG-binding domain protein 2/3, p55-binding region, protein family. wikidata.org.
[7] ↑ Methyl-CpG binding domain protein 2 — part of (P361): Methyl-CpG binding protein 2/3, C-terminal domain, protein family. wikidata.org.
[8] ↑ Methyl-CpG binding domain protein 2 — part of (P361): Methyl-CpG DNA binding domain, protein family. wikidata.org.
[9] ↑ Methyl-CpG binding domain protein 2 — has part(s) (P527): Methyl-CpG-binding domain protein 2/3, p55-binding region. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Methyl-CpG binding domain protein 2 — has part(s) (P527): Methyl-CpG binding protein 2/3, C-terminal domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Methyl-CpG binding domain protein 2 — has part(s) (P527): methyl-CpG DNA binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Methyl-CpG binding domain protein 2 — RefSeq protein ID (P637): NP_001298000. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ Methyl-CpG binding domain protein 2 — RefSeq protein ID (P637): NP_034903. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ Methyl-CpG binding domain protein 2 — RefSeq protein ID (P637): XP_006525774. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ Methyl-CpG binding domain protein 2 — RefSeq protein ID (P637): XP_036016901. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Methyl-CpG binding domain protein 2 — molecular function (P680): DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Methyl-CpG binding domain protein 2 — molecular function (P680): protein domain specific binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Methyl-CpG binding domain protein 2 — molecular function (P680): methyl-CpG binding. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Methyl-CpG binding domain protein 2 — molecular function (P680): C2H2 zinc finger domain binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Methyl-CpG binding domain protein 2 — molecular function (P680): protein binding. Mechanical Loading in Osteocytes Induces Formation of a Src/Pyk2/MBD2 Complex That Suppresses Anabolic Gene Expression. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Methyl-CpG binding domain protein 2 — molecular function (P680): siRNA binding. Components of the DNA methylation system of chromatin control are RNA-binding proteins. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Methyl-CpG binding domain protein 2 — molecular function (P680): mRNA binding. Components of the DNA methylation system of chromatin control are RNA-binding proteins. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Methyl-CpG binding domain protein 2 — molecular function (P680): chromatin binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Methyl-CpG binding domain protein 2 — molecular function (P680): methyl-CpG binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Methyl-CpG binding domain protein 2 — cell component (P681): cytoplasm. Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Methyl-CpG binding domain protein 2 — cell component (P681): histone deacetylase complex. Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Methyl-CpG binding domain protein 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Methyl-CpG binding domain protein 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/methyl-cpg-binding-domain-protein-2-q21986534

MLA

“Methyl-CpG binding domain protein 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/methyl-cpg-binding-domain-protein-2-q21986534.

BibTeX

@misc{4ortxyz_methyl-cpg-binding-domain-protein-2-q21986534_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Methyl-CpG binding domain protein 2}}, year = {2026}, url = {https://4ort.xyz/entity/methyl-cpg-binding-domain-protein-2-q21986534}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Methyl-CpG binding domain protein 2 — https://4ort.xyz/entity/methyl-cpg-binding-domain-protein-2-q21986534 (retrieved 2026-05-03)

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